(Q33336612)

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Pharmacological inhibition of nicotinamide phosphoribosyltransferase/visfatin enzymatic activity identifies a new inflammatory pathway linked to NAD

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scholarly article

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Europe PubMed Central

25 July 2017

Pharmacological inhibition of nicotinamide phosphoribosyltransferase/visfatin enzymatic activity identifies a new inflammatory pathway linked to NAD (English)

1 reference

Europe PubMed Central

25 July 2017

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1 reference

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Oberdan Leo

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Europe PubMed Central

25 July 2017

author name string

Nathalie Busso

1

1 reference

Europe PubMed Central

25 July 2017

Mahir Karababa

2

1 reference

Europe PubMed Central

25 July 2017

Massimo Nobile

3

1 reference

Europe PubMed Central

25 July 2017

Aline Rolaz

4

1 reference

Europe PubMed Central

25 July 2017

Frédéric Van Gool

5

1 reference

Europe PubMed Central

25 July 2017

Mara Galli

6

1 reference

Europe PubMed Central

25 July 2017

Alexander So

8

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Europe PubMed Central

25 July 2017

Thibaut De Smedt

9

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Europe PubMed Central

25 July 2017

language of work or name

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publication date

21 May 2008

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Europe PubMed Central

25 July 2017

1 reference

Europe PubMed Central

25 July 2017

3

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Europe PubMed Central

25 July 2017

e2267

1 reference

Europe PubMed Central

25 July 2017

5

1 reference

Europe PubMed Central

25 July 2017

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Creative Commons Attribution 4.0 International

21 May 2008

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April 2022 Public Data File from Crossref

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Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

Visfatin is released from 3T3-L1 adipocytes via a non-classical pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

Sirtuins in mammals: insights into their biological function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

The regulation of nicotinamide adenine dinucleotide biosynthesis by Nampt/PBEF/visfatin in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

Sirtuins as potential targets for metabolic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

Chemopotentiating effects of a novel NAD biosynthesis inhibitor, FK866, in combination with antineoplastic agents

1 reference

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21 June 2018

Inhibition of angiogenic pathways in rheumatoid arthritis: potential for therapeutic targeting.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

Visfatin in adipocytes is upregulated by hypoxia through HIF1alpha-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

Methotrexate in rheumatoid arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

Crystal structure of visfatin/pre-B cell colony-enhancing factor 1/nicotinamide phosphoribosyltransferase, free and in complex with the anti-cancer agent FK-866

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

Hypoxic induction of human visfatin gene is directly mediated by hypoxia-inducible factor-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents.

1 reference

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21 June 2018

Inhibition of IL-1, IL-6, and TNF-alpha in immune-mediated inflammatory diseases

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21 June 2018

The histone deacetylase inhibitor ITF2357 reduces production of pro-inflammatory cytokines in vitro and systemic inflammation in vivo

1 reference

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21 June 2018

Changes in plasma levels of fat-derived hormones adiponectin, leptin, resistin and visfatin in patients with rheumatoid arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

Hypoxia and angiogenesis in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

RETRACTED: Visfatin: a protein secreted by visceral fat that mimics the effects of insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

Pre-B cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

Metalloproteinases, inflammation, and rheumatoid arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

Reconstructing eukaryotic NAD metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

The functional role of poly(ADP-ribose)polymerase 1 as novel coactivator of NF-kappaB in inflammatory disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

Cytokines and anti-cytokine biologicals in autoimmunity: present and future

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

WK175, a novel antitumor agent, decreases the intracellular nicotinamide adenine dinucleotide concentration and induces the apoptotic cascade in human leukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

Human macrophage activation programs induced by bacterial pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

Genomic organization of the gene coding for human pre-B-cell colony enhancing factor and expression in human fetal membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

New functions of a long-known molecule. Emerging roles of NAD in cellular signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

Protective effects of niacinamide in staphylococcal enterotoxin-B-induced toxicity

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21 June 2018

Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

Angiogenesis inhibition suppresses collagen arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2377336

21 June 2018

TNF regulates cellular NAD+ metabolism in primary macrophages.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002267

21 January 2018

Pre-B-cell colony-enhancing factor as a potential novel biomarker in acute lung injury.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002267

21 January 2018

Visfatin, an adipocytokine with proinflammatory and immunomodulating properties.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002267

21 January 2018

Regulation of pre-B cell colony-enhancing factor by STAT-3-dependent interleukin-6 trans-signaling: implications in the pathogenesis of rheumatoid arthritis.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002267

21 January 2018

Pre-B cell colony-enhancing factor/visfatin, a new marker of inflammation in rheumatoid arthritis with proinflammatory and matrix-degrading activities

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002267

21 January 2018

Metabolic signatures associated with a NAD synthesis inhibitor-induced tumor apoptosis identified by 1H-decoupled-31P magnetic resonance spectroscopy

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002267

21 January 2018

New functions of a long-known molecule

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002267

21 January 2018

Retraction: Visfatin: a protein secreted by visceral fat that mimics the effects of insulin.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002267

21 January 2018

Visfatin promotes angiogenesis by activation of extracellular signal-regulated kinase 1/2.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002267

21 January 2018

Synovial proliferation differentially affects hypoxia in the joint cavities of rheumatoid arthritis and osteoarthritis patients.

1 reference

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31 October 2018

Antiangiogenic potency of FK866/K22.175, a new inhibitor of intracellular NAD biosynthesis, in murine renal cell carcinoma.

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Newly discovered anti-inflammatory properties of the benzamides and nicotinamides

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https://pubmed.ncbi.nlm.nih.gov/18493620

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10.1371/JOURNAL.PONE.0002267

1 reference

Europe PubMed Central

25 July 2017

2008PLoSO...3.2267B

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1 reference

Europe PubMed Central

25 July 2017

1 reference

Europe PubMed Central

25 July 2017

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