(Q33344253)

26 July 2017

title

Relative effects of mutability and selection on single nucleotide polymorphisms in transcribed regions of the human genome (English)

1 reference

single-nucleotide polymorphism

26 July 2017

main subject

1 reference

3

Christopher I Amos

1 reference

26 July 2017

2

Olga Y Gorlova

1 reference

26 July 2017

1

Ivan P Gorlov

1 reference

26 July 2017

language of work or name

English

0 references

publication date

17 June 2008

1 reference

26 July 2017

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26 July 2017

volume

9

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26 July 2017

page(s)

292

1 reference

RCPdb: An evolutionary classification and codon usage database for repeat-containing proteins

26 July 2017

cites work

1 reference

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21 June 2018

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Evolutionary anatomies of positions and types of disease-associated and neutral amino acid mutations in the human genome

21 June 2018

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A gene-centric approach to genome-wide association studies

21 June 2018

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A map of recent positive selection in the human genome

21 June 2018

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A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters

21 June 2018

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Ascertainment bias in studies of human genome-wide polymorphism.

21 June 2018

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Natural selection on protein-coding genes in the human genome

21 June 2018

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Initial sequence of the chimpanzee genome and comparison with the human genome

21 June 2018

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Finishing the euchromatic sequence of the human genome

21 June 2018

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Bayesian Markov chain Monte Carlo sequence analysis reveals varying neutral substitution patterns in mammalian evolution

21 June 2018

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21 June 2018

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Widespread purifying selection at polymorphic sites in human protein-coding loci

21 June 2018

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Nucleotide Frequency Variation Across Human Genes

21 June 2018

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Impact of selection, mutation rate and genetic drift on human genetic variation.

21 June 2018

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Distribution and characterization of regulatory elements in the human genome

21 June 2018

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On the allelic spectrum of human disease

21 June 2018

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Positive and negative selection on the human genome

21 June 2018

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21 June 2018

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Estimate of the mutation rate per nucleotide in humans

21 June 2018

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Use of molecular variation in the NCBI dbSNP database

21 June 2018

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dbSNP: a database of single nucleotide polymorphisms

21 June 2018

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Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis

21 June 2018

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Characterization of single-nucleotide polymorphisms in coding regions of human genes

21 June 2018

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Sequence diversity in 36 candidate genes for cardiovascular disorders

21 June 2018

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Case-control association studies in complex traits--the end of an era?

21 June 2018

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Constitutively methylated CpG dinucleotides as mutation hot spots in the retinoblastoma gene (RB1).

21 June 2018

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The rate of CpG mutation in Alu repetitive elements within the p53 tumor suppressor gene in the primate germline

21 June 2018

1 reference

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Context dependence, ancestral misidentification, and spurious signatures of natural selection.

21 June 2018

1 reference

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The rate, not the spectrum, of base pair substitutions changes at a GC-content transition in the human NF1 gene region: implications for the evolution of the mammalian genome structure

31 October 2018

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CpG + CpNpG analysis of protein-coding sequences from tomato

31 October 2018

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A personalized and automated dbSNP surveillance system.

31 October 2018

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Nonsynonymous SNPs: validation characteristics, derived allele frequency patterns, and suggestive evidence for natural selection.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442617

Human SNPs reveal no evidence of frequent positive selection

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442617

Substitution rate and structural divergence of 5'UTR evolution: comparative analysis between human and cynomolgus monkey cDNAs

31 October 2018

1 reference

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From context-dependence of mutations to molecular mechanisms of mutagenesis

31 October 2018

1 reference

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Phylogenetic estimation of context-dependent substitution rates by maximum likelihood

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442617

Investigating single nucleotide polymorphism (SNP) density in the human genome and its implications for molecular evolution

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442617

Low hanging fruit: a subset of human cSNPs is both highly non-uniform and predictable

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442617

Case-control association studies in pharmacogenetics

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442617

Understanding human disease mutations through the use of interspecific genetic variation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442617

Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: similarities with the p53 mutation spectrum in smoking-associated lung cancers.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442617

CpG transition strand asymmetry and hitch-hiking mutations as measures of tumorigenic selection in shaping the p53 mutation spectrum

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442617

Selective Pressures at a Codon-level Predict Deleterious Mutations in Human Disease Genes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2442617

Genetic analysis of complex diseases

31 October 2018

1 reference

12 December 2020

The new genomics: global views of biology

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12 December 2020

Variations on a theme: cataloging human DNA sequence variation

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12 December 2020

Strength of the purifying selection against different categories of the point mutations in the coding regions of the human genome

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12 December 2020

Rates of conservative and radical nonsynonymous nucleotide substitutions in mammalian nuclear genes

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12 December 2020

Direct estimates of human per nucleotide mutation rates at 20 loci causing Mendelian diseases

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12 December 2020

Negligible validation rate for public domain stop-codon SNPs

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12 December 2020

Case-control association studies with matching and genomic controlling

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Codon usage in the vertebrate hemoglobins and its implications

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12 December 2020

Are CpG sites mutation hot spots in the dystrophin gene?

1 reference

12 December 2020

Genetic analysis of complex diseases

1 reference

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Identifiers

DOI

10.1186/1471-2164-9-292

1 reference

Dimensions Publication ID

26 July 2017

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2164-9-292

9 September 2019

1 reference

26 July 2017

1 reference