(Q33352228)

26 July 2017

Structure-based development of novel adenylyl cyclase inhibitors (English)

1 reference

26 July 2017

Lonny R Levin

5

0 references

Jochen Buck

6

object named as

Jochen Buck

1 reference

26 July 2017

7

Clemens Steegborn

1 reference

26 July 2017

Christine Schlicker

1

1 reference

26 July 2017

Annika Rauch

2

1 reference

26 July 2017

Ken C Hess

3

1 reference

26 July 2017

Barbara Kachholz

4

1 reference

26 July 2017

language of work or name

English

0 references

publication date

17 July 2008

1 reference

Journal of Medicinal Chemistry

26 July 2017

1 reference

26 July 2017

51

1 reference

26 July 2017

15

1 reference

26 July 2017

4456-4464

1 reference

Activation and inhibition of adenylyl cyclase isoforms by forskolin analogs.

26 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Virtual screening strategies in drug discovery

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Drug therapy aimed at adenylyl cyclase to regulate cyclic nucleotide signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Molecular details of cAMP generation in mammalian cells: a tale of two systems

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Phosphodiesterases in the CNS: targets for drug development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

The "soluble" adenylyl cyclase in sperm mediates multiple signaling events required for fertilization

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

A novel mechanism for adenylyl cyclase inhibition from the crystal structure of its complex with catechol estrogen

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Bicarbonate activation of adenylyl cyclase via promotion of catalytic active site closure and metal recruitment

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Virtual screening of human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase against the NCI diversity set by use of AutoDock to identify novel nonfolate inhibitors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Tyrphostins are inhibitors of guanylyl and adenylyl cyclases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Isoforms of mammalian adenylyl cyclase: multiplicities of signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Differential inhibition of adenylyl cyclase isoforms and soluble guanylyl cyclase by purine and pyrimidine nucleotides.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

The class III adenylyl cyclases: multi-purpose signalling modules

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Bicarbonate-regulated Adenylyl Cyclase (sAC) Is a Sensor That Regulates pH-dependent V-ATPase Recycling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Metal Coordination-Based Inhibitors of Adenylyl Cyclase: Novel Potent P-Site Antagonists

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Isoform-targeted regulation of cardiac adenylyl cyclase.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Kinetic properties of "soluble" adenylyl cyclase. Synergism between calcium and bicarbonate

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

CO(2)/HCO(3)(-)-responsive soluble adenylyl cyclase as a putative metabolic sensor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Identification and functional analysis of splice variants of the germ cell soluble adenylyl cyclase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Regulation and role of adenylyl cyclase isoforms

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Molecular basis for P-site inhibition of adenylyl cyclase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Specific expression of soluble adenylyl cyclase in male germ cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Two-metal-Ion catalysis in adenylyl cyclase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

The interactions of adenylate cyclases with P-site inhibitors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Cytosolic adenylyl cyclase defines a unique signaling molecule in mammals

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Fluorescent guanine nucleotide analogs and G protein activation.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Inhibition of the soluble form of testis adenylate cyclase by catechol estrogens and other catechols

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Cloning and characterization of the human soluble adenylyl cyclase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Structural basis for the inhibition of mammalian membrane adenylyl cyclase by 2 '(3')-O-(N-Methylanthraniloyl)-guanosine 5 '-triphosphate

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Direct inhibition of type 5 adenylyl cyclase prevents myocardial apoptosis without functional deterioration

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Soluble adenylyl cyclase as an evolutionarily conserved bicarbonate sensor.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082441

Inhibition of adenylyl cyclase by acyclic nucleoside phosphonate antiviral agents

31 October 2018

1 reference

12 December 2020

Mechanism of nucleotide release from Rho by the GDP dissociation stimulator protein

1 reference

12 December 2020

Isoform-specific regulation of adenylyl cyclase by oxidized catecholamines

1 reference

12 December 2020

Kinetic Analysis of Interaction of Eukaryotic Release Factor 3 with Guanine Nucleotides

1 reference

12 December 2020

Identifiers

DOI

10.1021/JM800481Q

1 reference

26 July 2017

1 reference

26 July 2017

1 reference