(Q33373601)

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Filling the concept with data: integrating data from different in vitro and in silico assays on skin sensitizers to explore the battery approach for animal-free skin sensitization testing

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scholarly article

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Europe PubMed Central

PubMed publication ID

26 July 2017

Filling the concept with data: integrating data from different in vitro and in silico assays on skin sensitizers to explore the battery approach for animal-free skin sensitization testing (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

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Andreas Natsch

1

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Roger Emter

2

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Europe PubMed Central

PubMed publication ID

26 July 2017

Graham Ellis

3

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Europe PubMed Central

PubMed publication ID

26 July 2017

publication date

1 October 2008

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Europe PubMed Central

PubMed publication ID

26 July 2017

Toxicological Sciences

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Europe PubMed Central

PubMed publication ID

26 July 2017

107

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Europe PubMed Central

PubMed publication ID

26 July 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

106-121

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Europe PubMed Central

PubMed publication ID

26 July 2017

Activation of U937 cells by contact sensitizers: CD86 expression is independent of apoptosis

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

Characterization of the sensitizing potential of chemicals by in vitro analysis of dendritic cell activation and skin penetration

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

Local lymph node assay - validation, conduct and use in practice

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

Threshold for classification as a skin sensitizer in the local lymph node assay: a statistical evaluation.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

A skin-like cytochrome P450 cocktail activates prohaptens to contact allergenic metabolites

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

Describing the validity of carcinogen screening tests

1 reference

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21 January 2018

Analysis of interleukin-1alpha (IL-1alpha) and interleukin-8 (IL-8) expression and release in in vitro reconstructed human epidermis for the prediction of in vivo skin irritation and/or sensitization

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

Skin sensitization: modeling based on skin metabolism simulation and formation of protein conjugates

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

The role of Keap1 in cellular protective responses

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

Local lymph node assay (LLNA) for detection of sensitization capacity of chemicals

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

A chemical dataset for evaluation of alternative approaches to skin-sensitization testing.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

Development of a peptide reactivity assay for screening contact allergens

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

A future approach to measuring relative skin sensitising potency: a proposal

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

Nrf2 activation by sulforaphane restores the age-related decrease of T(H)1 immunity: role of dendritic cells

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

Classification of contact allergens according to potency: proposals

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

Role of p38 MAPK in the selective release of IL-8 induced by chemical allergen in naive THp-1 cells

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

Skin sensitizers induce antioxidant response element dependent genes: application to the in vitro testing of the sensitization potential of chemicals

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

Utility and limitations of a peptide reactivity assay to predict fragrance allergens in vitro.

1 reference

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21 January 2018

Mechanistic applicability domain classification of a local lymph node assay dataset for skin sensitization

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

Gene expression changes in peripheral blood-derived dendritic cells following exposure to a contact allergen

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

Development of an in vitro skin sensitization test using human cell lines; human Cell Line Activation Test (h-CLAT). II. An inter-laboratory study of the h-CLAT.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

Generation of a stable antioxidant response element-driven reporter gene cell line and its use to show redox-dependent activation of nrf2 by cancer chemotherapeutic agents.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

Activation of the Nrf2/antioxidant response pathway increases IL-8 expression

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFN204

21 January 2018

Identifiers

10.1093/TOXSCI/KFN204

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

ResearchGate publication ID

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