(Q33374475)

26 July 2017

title

A chemical compound that stimulates the human homologous recombination protein RAD51 (English)

1 reference

26 July 2017

6

Ralph R Weichselbaum

1 reference

26 July 2017

author name string

Krishanthi Jayathilaka

1

1 reference

26 July 2017

Sean D Sheridan

2

1 reference

26 July 2017

Tyler D Bold

3

1 reference

26 July 2017

Katarzyna Bochenska

4

1 reference

26 July 2017

Hillary L Logan

5

1 reference

26 July 2017

Douglas K Bishop

7

1 reference

26 July 2017

Philip P Connell

8

1 reference

26 July 2017

language of work or name

English

0 references

publication date

7 October 2008

1 reference

Proceedings of the National Academy of Sciences of the United States of America

26 July 2017

published in

1 reference

26 July 2017

volume

105

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26 July 2017

issue

41

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26 July 2017

page(s)

15848-15853

1 reference

RAD51 up-regulation bypasses BRCA1 function and is a common feature of BRCA1-deficient breast tumors

26 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Stabilization of RAD-51-DNA filaments via an interaction domain in Caenorhabditis elegans BRCA2

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Crystal structure of a Rad51 filament

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Ca2+ activates human homologous recombination protein Rad51 by modulating its ATPase activity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Dynamic control of Rad51 recombinase by self-association and interaction with BRCA2

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Comparison of the sulforhodamine B assay and the clonogenic assay for in vitro chemoradiation studies

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Insights into DNA recombination from the structure of a RAD51-BRCA2 complex

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Mutations in yeast Rad51 that partially bypass the requirement for Rad55 and Rad57 in DNA repair by increasing the stability of Rad51-DNA complexes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Identification and purification of two distinct complexes containing the five RAD51 paralogs

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Saccharomyces cerevisiae Dmc1 protein promotes renaturation of single-strand DNA (ssDNA) and assimilation of ssDNA into homologous super-coiled duplex DNA.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Domain structure and dynamics in the helical filaments formed by RecA and Rad51 on DNA.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Assembly of RecA-like recombinases: distinct roles for mediator proteins in mitosis and meiosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Homologous recombinational repair of DNA ensures mammalian chromosome stability

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

The essential functions of human Rad51 are independent of ATP hydrolysis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Catalysis of homologous DNA pairing by yeast Rad51 and Rad54 proteins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Activities of human recombination protein Rad51.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Purification and characterization of the human Rad51 protein, an analogue of E. coli RecA

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

The helicity of DNA in complexes with recA protein

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Cooperative and noncooperative binding of protein ligands to nucleic acid lattices: experimental approaches to the determination of thermodynamic parameters.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Intercalators promote the binding of RecA protein to double-stranded DNA

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Structural data suggest that the active and inactive forms of the RecA filament are not simply interconvertible

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

ADP stabilizes the human Rad51-single stranded DNA complex and promotes its DNA annealing activity

14 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808046105

Biochemical characterization of the human RAD51 protein. III. Modulation of DNA binding by adenosine nucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808046105

Conformational changes modulate the activity of human RAD51 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808046105

Calcium ion promotes yeast Dmc1 activity via formation of long and fine helical filaments with single-stranded DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808046105

The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2572930

Visualizing the assembly of human Rad51 filaments on double-stranded DNA

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18840682

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0808046105

1 reference

26 July 2017

0 references

1 reference

26 July 2017

1 reference