(Q33380283)

26 July 2017

title

Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors (English)

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26 July 2017

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N Schuldt

5

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author name string

D M Appledorn

1

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26 July 2017

A McBride

2

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26 July 2017

S Seregin

3

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26 July 2017

J M Scott

4

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26 July 2017

A Kiang

6

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26 July 2017

S Godbehere

7

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26 July 2017

A Amalfitano

8

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26 July 2017

publication date

10 July 2008

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26 July 2017

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26 July 2017

volume

15

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26 July 2017

issue

24

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26 July 2017

page(s)

1606-1617

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Enhanced breadth of CD4 T-cell immunity by DNA prime and adenovirus boost immunization to human immunodeficiency virus Env and Gag immunogens

26 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Development of a preventive vaccine for Ebola virus infection in primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Protection of mice and poultry from lethal H5N1 avian influenza virus through adenovirus-based immunization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Immune response to recombinant adenovirus in humans: capsid components from viral input are targets for vector-specific cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Vaccination with replication-deficient recombinant adenoviruses encoding the main surface antigens of toxoplasma gondii induces immune response and protection against infection in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Complement activation by recombinant adenoviruses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Adenoviral infection induces a multi-faceted innate cellular immune response that is mediated by the toll-like receptor pathway in A549 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Recombinant adenovirus vectors activate the alternative complement pathway, leading to the binding of human complement protein C3 independent of anti-ad antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Multiple innate inflammatory responses induced after systemic adenovirus vector delivery depend on a functional complement system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

The role of complement in inflammation and adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

The role of complement in inflammation and phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

The mannan-binding lectin pathway of complement activation: biology and disease association

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

The complement system in regulation of adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Wild-type adenoviruses from groups A-F evoke unique innate immune responses, of which HAd3 and SAd23 are partially complement dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Activation of p38 and ERK signaling during adenovirus vector cell entry lead to expression of the C-X-C chemokine IP-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Adenovirus serotype 5 hexon is critical for virus infection of hepatocytes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Adenovirus Binding to Blood Factors Results in Liver Cell Infection and Hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Adenovirus serotype 5 hexon mediates liver gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Rapid Kupffer cell death after intravenous injection of adenovirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Intravenous administration of replication-incompetent adenovirus to rhesus monkeys induces thrombocytopenia by increasing in vivo platelet clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Toll-like receptor 9 triggers an innate immune response to helper-dependent adenoviral vectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Innate immune response to adenoviral vectors is mediated by both Toll-like receptor-dependent and -independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

The innate immune response to adenovirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Adenoviral gene therapy leads to rapid induction of multiple chemokines and acute neutrophil-dependent hepatic injury in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Complement and Toll-like receptors: key regulators of adaptive immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Structure of C3b in complex with CRIg gives insights into regulation of complement activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Protective immune responses against West Nile virus are primed by distinct complement activation pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Complement is an essential component of the immune response to adeno-associated virus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Optimized immune response elicited by a DNA vaccine expressing pneumococcal surface protein a is characterized by a balanced immunoglobulin G1 (IgG1)/IgG2a ratio and proinflammatory cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Adenovirus vectors with the 100K gene deleted and their potential for multiple gene therapy applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Liver toxicities typically induced by first-generation adenoviral vectors can be reduced by use of E1, E2b-deleted adenoviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Persistence of an [E1-, polymerase-] adenovirus vector despite transduction of a neoantigen into immune-competent mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Genomic DNA from mice: a comparison of recovery methods and tissue sources.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Sensitivity of TLR4- and -7-induced NF kappa B1 p105-TPL2-ERK pathway to TNF-receptor-associated-factor-6 revealed by RNAi in mouse macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Type I interferon inhibits antibody responses induced by a chimpanzee adenovirus vector.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

7 January 2021

Fully deleted adenovirus persistently expressing GAA accomplishes long-term skeletal muscle glycogen correction in tolerant and nontolerant GSD-II mice

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

7 January 2021

Production and characterization of improved adenovirus vectors with the E1, E2b, and E3 genes deleted

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

7 January 2021

Arrestin-2 and G protein-coupled receptor kinase 5 interact with NFkappaB1 p105 and negatively regulate lipopolysaccharide-stimulated ERK1/2 activation in macrophages

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.114

7 January 2021

Identifiers

DOI

10.1038/GT.2008.114

1 reference

Dimensions Publication ID

26 July 2017

1035764163

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1 reference