(Q33381294)

26 July 2017

title

The pros and cons of immunomodulatory IL-10 gene therapy with recombinant AAV in a Cftr-/- -dependent allergy mouse model (English)

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26 July 2017

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Martha Campbell-Thompson

object named as

M Campbell-Thompson

5

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author name string

C Mueller

1

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26 July 2017

S A Braag

2

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26 July 2017

A T Martino

3

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26 July 2017

Q Tang

4

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26 July 2017

T R Flotte

6

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26 July 2017

publication date

25 September 2008

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26 July 2017

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26 July 2017

volume

16

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26 July 2017

issue

2

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26 July 2017

page(s)

172-183

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https://scigraph.springernature.com/pub.10.1038/gt.2008.156

26 July 2017

exact match

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cites work

Characteristic multiorgan pathology of cystic fibrosis in a long-living cystic fibrosis transmembrane regulator knockout murine model

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Lung pathology in response to repeated exposure to Staphylococcus aureus in congenic residual function cystic fibrosis mice does not increase in response to decreased CFTR levels or increased bacterial load

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Lung infections associated with cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Fluid transport across cultures of human tracheal glands is altered in cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Regulation of the depth and composition of airway surface liquid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Macromolecular complexes of cystic fibrosis transmembrane conductance regulator and its interacting partners

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Inhibition by TNF-alpha and IL-4 of cationic lipid mediated gene transfer in cystic fibrosis tracheal gland cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

The role of airway epithelium and blood neutrophils in the inflammatory response in cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Neutrophil recruitment and airway epithelial cell involvement in chronic cystic fibrosis lung disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Monitoring inflammation in CF. Cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Exaggerated activation of nuclear factor-kappaB and altered IkappaB-beta processing in cystic fibrosis bronchial epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Reduced IL-10 secretion by CD4+ T lymphocytes expressing mutant cystic fibrosis transmembrane conductance regulator (CFTR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Inflammatory cytokines in cystic fibrosis lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Prolonged inflammatory response to acute Pseudomonas challenge in interleukin-10 knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Interleukin-10 is a natural suppressor of cytokine production and inflammation in a murine model of allergic bronchopulmonary aspergillosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Animal models of allergic bronchopulmonary aspergillosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Increased sensitivity to IL-4 in cystic fibrosis patients with allergic bronchopulmonary aspergillosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Pulmonary T(H)2 response in Pseudomonas aeruginosa-infected patients with cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Reversible airway obstruction in cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Maxillary sinusitis as a surrogate model for CF gene therapy clinical trials in patients with antrostomies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Prevalence of allergic bronchopulmonary aspergillosis in cystic fibrosis in an area with a high frequency of atopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Mucosal inflammation in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

21 January 2018

Asthma and inflammation

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Inflammatory response in airway epithelial cells isolated from patients with cystic fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Interleukin-10 therapy--review of a new approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Kinetics of IL-10-induced gene expression in human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Excessive inflammatory response of cystic fibrosis mice to bronchopulmonary infection with Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Enhanced IgE allergic response to Aspergillus fumigatus in CFTR-/- mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Viral IL-10 gene therapy inhibits TNF-alpha and IL-1 beta, not IL-6, in the newborn endotoxemic mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

IL-10 gene therapy prevents TNBS-induced colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Systemic overexpression of IL-10 induces CD4+CD25+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease. The Interleukin 10 Inflammatory Bowel Disease Cooperative Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Sustained secretion of human alpha-1-antitrypsin from murine muscle transduced with adeno-associated virus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Adeno-associated virus vector-mediated IL-10 gene delivery prevents type 1 diabetes in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Interleukin 10-induced thrombocytopenia in normal healthy adult volunteers: evidence for decreased platelet production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Inefficient gene transfer by adenovirus vector to cystic fibrosis airway epithelia of mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

Multicenter Randomized Controlled Trial of Withdrawal of Inhaled Corticosteroids in Cystic Fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

The molecular pathology of cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

7 January 2021

Binding of Pseudomonas aeruginosa to respiratory epithelial cells from patients with various mutations in the cystic fibrosis transmembrane regulator

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

7 January 2021

Normal bronchial epithelial cells constitutively produce the anti-inflammatory cytokine interleukin-10, which is downregulated in cystic fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

7 January 2021

Altered respiratory epithelial cell cytokine production in cystic fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

7 January 2021

The bronchoalveolar lavage fluid of cystic fibrosis lung transplant recipients demonstrates increased interleukin-8 and elastase and decreased IL-10

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

7 January 2021

Functional IL-10 deficiency in the lung of cystic fibrosis (cftr(-/-)) and IL-10 knockout mice causes increased expression and function of B7 costimulatory molecules on alveolar macrophages

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

7 January 2021

IL-4 is a potent modulator of ion transport in the human bronchial epithelium in vitro

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

7 January 2021

Increased expression of Interleukin-13 but not Interleukin-4 in cystic fibrosis patients

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

7 January 2021

The effect of a comprehensive, intensive inpatient treatment program on lung function and exercise capacity in patients with cystic fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

7 January 2021

Allergy in asthma. I. The dose relationship of allergy to severity of childhood asthma

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

7 January 2021

Prevalence of allergic bronchopulmonary aspergillosis and atopy in adult patients with cystic fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

7 January 2021

https://api.crossref.org/works/10.1038%2FGT.2008.156

1 reference

7 January 2021

Modification of transepithelial ion transport in human cultured bronchial epithelial cells by interferon-gamma

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

7 January 2021

Cytokine dysregulation in activated cystic fibrosis (CF) peripheral lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

7 January 2021

Dysregulated cytokine production in human cystic fibrosis bronchial epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

7 January 2021

Effects of adenovirus-expressing IL-10 in alleviating airway inflammation in asthma

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

7 January 2021

IL-10 attenuates excessive inflammation in chronic Pseudomonas infection in mice

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

7 January 2021

Influence of interleukin-10 on Aspergillus fumigatus infection in patients with cystic fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FGT.2008.156

7 January 2021

Identifiers

DOI

10.1038/GT.2008.156

1 reference

26 July 2017

1 reference