(Q33384179)

English

Targeting protein-protein interactions: suppression of Stat3 dimerization with rationally designed small-molecule, nonpeptidic SH2 domain binders

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

26 July 2017

Targeting protein-protein interactions: suppression of Stat3 dimerization with rationally designed small-molecule, nonpeptidic SH2 domain binders (English)

1 reference

Europe PubMed Central

26 July 2017

0 references

protein-protein interaction

1 reference

based on heuristic

inferred from title

object named as

William P Katt

4

0 references

author name string

Patrick T Gunning

1

1 reference

Europe PubMed Central

26 July 2017

Matthew P Glenn

2

1 reference

Europe PubMed Central

26 July 2017

Khandaker A Z Siddiquee

3

1 reference

Europe PubMed Central

26 July 2017

Eric Masson

5

1 reference

Europe PubMed Central

26 July 2017

Saïd M Sebti

6

1 reference

Europe PubMed Central

26 July 2017

James Turkson

7

1 reference

Europe PubMed Central

26 July 2017

Andrew D Hamilton

8

1 reference

Europe PubMed Central

26 July 2017

publication date

1 November 2008

1 reference

Europe PubMed Central

26 July 2017

1 reference

Europe PubMed Central

26 July 2017

9

1 reference

Europe PubMed Central

26 July 2017

17

1 reference

Europe PubMed Central

26 July 2017

2800-2803

1 reference

Europe PubMed Central

26 July 2017

Molecular approaches towards the inhibition of the signal transducer and activator of transcription 3 (Stat3) protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

21 June 2018

Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

21 June 2018

Isoform selective inhibition of STAT1 or STAT3 homo-dimerization via peptidomimetic probes: structural recognition of STAT SH2 domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

21 June 2018

Stattic: a small-molecule inhibitor of STAT3 activation and dimerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

21 June 2018

Solid-phase synthesis of Stat3 inhibitors incorporating O-carbamoylserine and O-carbamoylthreonine as glutamine mimics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

21 June 2018

A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

21 June 2018

STAT proteins as novel targets for cancer drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

21 June 2018

Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

21 June 2018

Inhibition of constitutive STAT3 activity sensitizes resistant non-Hodgkin's lymphoma and multiple myeloma to chemotherapeutic drug-mediated apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

21 June 2018

Stat proteins and oncogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

21 June 2018

Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

21 June 2018

Inhibition of protein-protein association by small molecules: approaches and progress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

21 June 2018

Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

21 June 2018

A simple, high-resolution method for establishing DNA binding affinity and sequence selectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

21 June 2018

STAT proteins as novel targets for cancer therapy. Signal transducer an activator of transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

21 June 2018

Transcription factor activity of STAT proteins: structural requirements and regulation by phosphorylation and interacting proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

21 June 2018

Development and validation of a genetic algorithm for flexible docking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

21 June 2018

Role of epidermal growth factor receptor and STAT-3 activation in autonomous proliferation of SUM-102PT human breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

21 June 2018

Structural basis for the binding of high affinity phosphopeptides to Stat3.

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200800291

21 January 2018

Investigation of the binding determinants of phosphopeptides targeted to the SRC homology 2 domain of the signal transducer and activator of transcription 3. Development of a high-affinity peptide inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

31 October 2018

A high-throughput fluorescence polarization assay for signal transducer and activator of transcription 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

31 October 2018

Identification of a high-affinity phosphopeptide inhibitor of Stat3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

31 October 2018

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728599

31 October 2018

Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/19006150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A fluorescent complex between ethidium bromide and nucleic acids. Physical-chemical characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/19006150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between binding and dynamics at SH2 domain interfaces

1 reference

https://pubmed.ncbi.nlm.nih.gov/19006150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Validating Stat3 in cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19006150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design and synthesis of a new, conformationally constrained, macrocyclic small-molecule inhibitor of STAT3 via 'click chemistry'

1 reference

https://pubmed.ncbi.nlm.nih.gov/19006150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An oxazole-based small-molecule Stat3 inhibitor modulates Stat3 stability and processing and induces antitumor cell effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/19006150

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/CBIC.200800291

1 reference

Europe PubMed Central

26 July 2017

1 reference

Europe PubMed Central

26 July 2017

1 reference

Europe PubMed Central

26 July 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q33384179&oldid=1953472175"