(Q33394363)

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BH3-only activator proteins Bid and Bim are dispensable for Bak/Bax-dependent thrombocyte apoptosis induced by Bcl-xL deficiency: molecular requisites for the mitochondrial pathway to apoptosis in platelets

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

BH3-only activator proteins Bid and Bim are dispensable for Bak/Bax-dependent thrombocyte apoptosis induced by Bcl-xL deficiency: molecular requisites for the mitochondrial pathway to apoptosis in platelets (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

apoptotic process

1 reference

based on heuristic

inferred from title

Takahiro Kodama

object named as

Takahiro Kodama

1

0 references

Naoki Hiramatsu

12

object named as

Naoki Hiramatsu

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Tetsuo Takehara

2

object named as

Tetsuo Takehara

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Tomohide Tatsumi

9

object named as

Tomohide Tatsumi

1 reference

Europe PubMed Central

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26 July 2017

7

object named as

Takuya Miyagi

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

14

object named as

Norio Hayashi

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

author name string

Hayato Hikita

3

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Satoshi Shimizu

4

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Minoru Shigekawa

5

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Wei Li

6

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Atsushi Hosui

8

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Hisashi Ishida

10

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Tatsuya Kanto

11

1 reference

Europe PubMed Central

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26 July 2017

Xiao-Ming Yin

13

1 reference

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26 July 2017

language of work or name

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publication date

2 March 2011

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Europe PubMed Central

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26 July 2017

Journal of Biological Chemistry

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Europe PubMed Central

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26 July 2017

286

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Europe PubMed Central

PubMed publication ID

26 July 2017

16

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

13905-13913

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Still embedded together binding to membranes regulates Bcl-2 protein interactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Thrombocytopenia exacerbates cholestasis-induced liver fibrosis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

The BCL-2 family reunion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

BH3-only protein bid participates in the Bcl-2 network in healthy liver cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Mcl-1 and Bcl-xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Comparative analyses of cell disruption methods for mitochondrial isolation in high-throughput proteomics study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

BAX activation is initiated at a novel interaction site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Bcl-XL inhibits membrane permeabilization by competing with Bax.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Bcl-2-regulated apoptosis: mechanism and therapeutic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Embedded together: the life and death consequences of interaction of the Bcl-2 family with membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Programmed anuclear cell death delimits platelet life span.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Life in the balance: how BH3-only proteins induce apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Apoptosis regulator bcl-w is essential for spermatogenesis but appears otherwise redundant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Testicular degeneration in Bclw-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Genetic transformation of mouse embryos by microinjection of purified DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Physiological functions of platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Human platelet secretion and aggregation induced by calcium ionophores. Inhibition by PGE1 and dibutyryl cyclic AMP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

21 June 2018

Apoptotic activity in stored human platelets

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.195370

21 January 2018

Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.195370

21 January 2018

Requirement of voltage-dependent anion channel 2 for pro-apoptotic activity of Bax.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.195370

21 January 2018

Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.195370

21 January 2018

Accelerated neutrophil apoptosis in mice lacking A1-a, a subtype of the bcl-2-related A1 gene.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.195370

21 January 2018

The anti-apoptotic Bcl-2 family member Mcl-1 promotes T lymphocyte survival at multiple stages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.195370

21 January 2018

Bcl-2 family proteins are essential for platelet survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077591

31 October 2018

Nonionic detergents induce dimerization among members of the Bcl-2 family

1 reference

https://pubmed.ncbi.nlm.nih.gov/21367852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in Bcl-2/Bax protein levels in platelets form part of an ionomycin-induced process that resembles apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21367852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies

1 reference

https://pubmed.ncbi.nlm.nih.gov/21367852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pf4-Cre transgenic mice allow the generation of lineage-restricted gene knockouts for studying megakaryocyte and platelet function in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/21367852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of apoptosis in human platelets during storage

1 reference

https://pubmed.ncbi.nlm.nih.gov/21367852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of Bcl-xL deamidation in human hepatocellular carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/21367852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic markers are increased in platelets stored at 37 degrees C

1 reference

https://pubmed.ncbi.nlm.nih.gov/21367852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo biotinylation demonstrates that reticulated platelets are the youngest platelets in circulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21367852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M110.195370

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

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