(Q33399096)

26 July 2017

title

The CXCR4/CXCR7/SDF-1 pathway contributes to the pathogenesis of Shiga toxin-associated hemolytic uremic syndrome in humans and mice (English)

1 reference

26 July 2017

Jason E Fish

9

0 references

Warren L Lee

object named as

Warren L Lee

14

0 references

Phillip I Tarr

20

object named as

Phillip I Tarr

1 reference

26 July 2017

21

W Conrad Liles

1 reference

26 July 2017

author name string

Tania N Petruzziello-Pellegrini

1

1 reference

26 July 2017

Darren A Yuen

2

1 reference

26 July 2017

Andrea V Page

3

1 reference

26 July 2017

Sajedabanu Patel

4

1 reference

26 July 2017

Anna M Soltyk

5

1 reference

26 July 2017

Charles C Matouk

6

1 reference

26 July 2017

Dennis K Wong

7

1 reference

26 July 2017

Paul J Turgeon

8

1 reference

26 July 2017

J J David Ho

10

1 reference

26 July 2017

Brent M Steer

11

1 reference

26 July 2017

Vahid Khajoee

12

1 reference

26 July 2017

Jayesh Tigdi

13

1 reference

26 July 2017

David G Motto

15

1 reference

26 July 2017

Andrew Advani

16

1 reference

26 July 2017

Richard E Gilbert

17

1 reference

26 July 2017

S Ananth Karumanchi

18

1 reference

26 July 2017

Lisa A Robinson

19

1 reference

26 July 2017

James L Brunton

22

1 reference

26 July 2017

Philip A Marsden

23

1 reference

26 July 2017

language of work or name

English

0 references

publication date

9 January 2012

1 reference

Journal of Clinical Investigation

26 July 2017

published in

1 reference

26 July 2017

volume

122

1 reference

26 July 2017

issue

2

1 reference

26 July 2017

page(s)

759-776

1 reference

Origins of the E. coli strain causing an outbreak of hemolytic-uremic syndrome in Germany

26 July 2017

cites work

1 reference

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21 June 2018

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Characterisation of the Escherichia coli strain associated with an outbreak of haemolytic uraemic syndrome in Germany, 2011: a microbiological study

21 June 2018

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Epidemic profile of Shiga-toxin-producing Escherichia coli O104:H4 outbreak in Germany

21 June 2018

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Shiga toxin B subunits induce VWF secretion by human endothelial cells and thrombotic microangiopathy in ADAMTS13-deficient mice

21 June 2018

1 reference

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CXCR7 functions as a scavenger for CXCL12 and CXCL11

21 June 2018

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Microarray analysis of retinal endothelial tip cells identifies CXCR4 as a mediator of tip cell morphology and branching

21 June 2018

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Effects of CXCR4 gene transfer on cardiac function after ischemia-reperfusion injury

21 June 2018

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Modifiers of von Willebrand factor identified by natural variation in inbred strains of mice

21 June 2018

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The CXCL12 (SDF-1)/CXCR4 axis is essential for the development of renal vasculature

21 June 2018

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CXCR4/CXCL12 hyperexpression plays a pivotal role in the pathogenesis of lupus.

21 June 2018

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AMD3100 is a CXCR7 ligand with allosteric agonist properties

21 June 2018

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Essential but differential role for CXCR4 and CXCR7 in the therapeutic homing of human renal progenitor cells.

21 June 2018

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Control of chemokine-guided cell migration by ligand sequestration

21 June 2018

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Bile salt-dependent lipase interacts with platelet CXCR4 and modulates thrombus formation in mice and humans.

21 June 2018

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Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7

21 June 2018

1 reference

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Plerixafor: AMD 3100, AMD3100, JM 3100, SDZ SID 791

21 June 2018

1 reference

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A murine model of HUS: Shiga toxin with lipopolysaccharide mimics the renal damage and physiologic response of human disease

21 June 2018

1 reference

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A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

21 June 2018

1 reference

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Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes

21 June 2018

1 reference

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Platelets secrete stromal cell-derived factor 1alpha and recruit bone marrow-derived progenitor cells to arterial thrombi in vivo

21 June 2018

1 reference

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An SDF-1 trap for myeloid cells stimulates angiogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Shiga toxin 2 and lipopolysaccharide induce human microvascular endothelial cells to release chemokines and factors that stimulate platelet function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Impaired CXCR4 signaling contributes to the reduced neovascularization capacity of endothelial progenitor cells from patients with coronary artery disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Shigatoxin triggers thrombotic thrombocytopenic purpura in genetically susceptible ADAMTS13-deficient mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Hemolytic uremic syndrome-associated Shiga toxins promote endothelial-cell secretion and impair ADAMTS13 cleavage of unusually large von Willebrand factor multimers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Stromal cell-derived factor-1alpha and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: von Hippel-Lindau loss-of-function induces expression of a ligand and its receptor

21 June 2018

1 reference

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Homing to hypoxia: HIF-1 as a mediator of progenitor cell recruitment to injured tissue

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

The expression of endothelial nitric-oxide synthase is controlled by a cell-specific histone code.

21 June 2018

1 reference

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Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Preferred analysis methods for Affymetrix GeneChips revealed by a wholly defined control dataset

21 June 2018

1 reference

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The role of CXCL12 in the organ-specific process of artery formation

21 June 2018

1 reference

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Chemokine expression in the monocytic cell line THP-1 in response to purified shiga toxin 1 and/or lipopolysaccharides

21 June 2018

1 reference

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Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

21 June 2018

1 reference

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Involvement of the chemokine receptor CXCR4 and its ligand stromal cell-derived factor 1alpha in breast cancer cell migration through human brain microvascular endothelial cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Identification of strain-specific variants of mouse Adamts13 gene encoding von Willebrand factor-cleaving protease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Regulation of proinflammatory cytokine expression by Shiga toxin 1 and/or lipopolysaccharides in the human monocytic cell line THP-1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Studies on the mechanism of experimental proteinuria

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Endothelial cell diversity revealed by global expression profiling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

A model of molecular interactions on short oligonucleotide microarrays

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Molecular and functional analysis of Shiga toxin–induced response patterns in human vascular endothelial cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Prothrombotic coagulation abnormalities preceding the hemolytic-uremic syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Shiga toxins induce, superinduce, and stabilize a variety of C-X-C chemokine mRNAs in intestinal epithelial cells, resulting in increased chemokine expression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Adenosine diphosphate strongly potentiates the ability of the chemokines MDC, TARC, and SDF-1 to stimulate platelet function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 infections

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Human microvascular endothelial cells are strongly sensitive to Shiga toxins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Verotoxin and ricin have novel effects on preproendothelin-1 expression but fail to modify nitric oxide synthase (ecNOS) expression and NO production in vascular endothelium

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

A novel, testis-specific mRNA transcript encoding an NH2-terminal truncated nitric-oxide synthase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Shiga toxin-associated hemolytic uremic syndrome: interleukin-1 beta enhancement of Shiga toxin cytotoxicity toward human vascular endothelial cells in vitro

21 June 2018

1 reference

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Endothelial heterogeneity in Shiga toxin receptors and responses.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Verotoxin induces hemorrhagic lesions in rat small intestine. Temporal alteration of vasoactive substances

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Maturational regulation of globotriaosylceramide, the Shiga-like toxin 1 receptor, in cultured human gut epithelial cells

21 June 2018

1 reference

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Nucleotide sequence analysis of the structural genes for Shiga-like toxin I encoded by bacteriophage 933J from Escherichia coli

21 June 2018

1 reference

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Properties of strains of Escherichia coli belonging to serogroup O157 with special reference to production of Vero cytotoxins VT1 and VT2

21 June 2018

1 reference

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Glycolipid binding of purified and recombinant Escherichia coli produced verotoxin in vitro.

21 June 2018

1 reference

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Hemolytic-uremic syndrome associated with a variant Shiga-like cytotoxin of Escherichia coli O111.

21 June 2018

1 reference

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Site of action of a Vero toxin (VT2) from Escherichia coli O157:H7 and of Shiga toxin on eukaryotic ribosomes. RNA N-glycosidase activity of the toxins.

21 June 2018

1 reference

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Continuous peritoneal infusion of Shiga-like toxin II (SLT II) as a model for SLT II-induced diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Infection by verocytotoxin-producing Escherichia coli

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Mutational analysis of the Shiga toxin and Shiga-like toxin II enzymatic subunits

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Characterization of Shiga-like toxin I B subunit purified from overproducing clones of the SLT-I B cistron

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Shiga toxin-associated hemolytic-uremic syndrome: combined cytotoxic effects of Shiga toxin, interleukin-1 beta, and tumor necrosis factor alpha on human vascular endothelial cells in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Molecular cloning and characterization of human endothelial nitric oxide synthase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Podocytes produce homeostatic chemokine stromal cell-derived factor-1/CXCL12, which contributes to glomerulosclerosis, podocyte loss and albuminuria in a mouse model of type 2 diabetes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

The (Pro)renin receptor: site-specific and functional linkage to the vacuolar H+-ATPase in the kidney.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Early postnatal lethality and cardiovascular defects in CXCR7-deficient mice

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Fluorescent microangiography (FMA): an improved tool to visualize the pulmonary microvasculature

31 October 2018

1 reference

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Post-transcriptional regulation of endothelial nitric-oxide synthase by an overlapping antisense mRNA transcript

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Identification of endothelial cell genes by combined database mining and microarray analysis

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Characterization of non-toxic mutant toxins of Vero toxin 1 that were constructed by replacing amino acids in the A subunit.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Hypoxia-inducible Expression of a Naturalcis-Antisense Transcript Inhibits Endothelial Nitric-oxide Synthase

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266777

Lung-selective gene responses to alveolar hypoxia: potential role for the bone morphogenetic antagonist gremlin in pulmonary hypertension

10 December 2018

1 reference

12 December 2020

Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice

1 reference

12 December 2020

VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells

1 reference

12 December 2020

SDF1-3'A gene polymorphism is associated with chronic myeloproliferative disease and thrombotic events

1 reference

12 December 2020

Stromal cell-derived factor-1 and macrophage-derived chemokine: 2 chemokines that activate platelets

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI57313

1 reference

26 July 2017

1 reference

26 July 2017

1 reference