(Q33404963)

26 July 2017

title

HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis (English)

1 reference

26 July 2017

Ben Wielockx

25

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Joachim Fandrey

object named as

Joachim Fandrey

23

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David R Greaves

object named as

David R Greaves

20

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Triantafyllos Chavakis

22

object named as

Triantafyllos Chavakis

1 reference

26 July 2017

Kristin Franke

1

1 reference

26 July 2017

Joanna Kalucka

2

1 reference

26 July 2017

Soulafa Mamlouk

3

1 reference

26 July 2017

Rashim Pal Singh

4

1 reference

26 July 2017

Antje Muschter

5

1 reference

26 July 2017

Alexander Weidemann

6

1 reference

26 July 2017

Vasuprada Iyengar

7

1 reference

26 July 2017

Steffen Jahn

8

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26 July 2017

Kathrin Wieczorek

9

1 reference

26 July 2017

Kathrin Geiger

10

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26 July 2017

Michael Muders

11

1 reference

26 July 2017

Alex M Sykes

12

1 reference

26 July 2017

David M Poitz

13

1 reference

26 July 2017

Tatsiana Ripich

14

1 reference

26 July 2017

Teresa Otto

15

1 reference

26 July 2017

Sybille Bergmann

16

1 reference

26 July 2017

Georg Breier

17

1 reference

26 July 2017

Gustavo Baretton

18

1 reference

26 July 2017

Guo-Hua Fong

19

1 reference

26 July 2017

Stefan Bornstein

21

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26 July 2017

Max Gassmann

24

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26 July 2017

language of work or name

English

0 references

publication date

20 December 2012

1 reference

26 July 2017

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26 July 2017

volume

121

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26 July 2017

issue

8

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26 July 2017

page(s)

1436-1445

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describes a project that uses

26 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3628111/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Isolation and characterization of renal erythropoietin-producing cells from genetically produced anemia mice

21 June 2018

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21 June 2018

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21 June 2018

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A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo

21 June 2018

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Involvement of oxygen-sensing pathways in physiologic and pathologic erythropoiesis

21 June 2018

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Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization

21 June 2018

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21 June 2018

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Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology

21 June 2018

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Novel exon 12 mutations in the HIF2A gene associated with erythrocytosis

21 June 2018

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A gain-of-function mutation in the HIF2A gene in familial erythrocytosis

21 June 2018

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Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure

21 June 2018

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Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins

21 June 2018

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A novel erythrocytosis-associated PHD2 mutation suggests the location of a HIF binding groove

21 June 2018

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Molecular insights into stress erythropoiesis

21 June 2018

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Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo

21 June 2018

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Acute postnatal ablation of Hif-2alpha results in anemia

21 June 2018

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Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2

21 June 2018

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21 June 2018

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A family with erythrocytosis establishes a role for prolyl hydroxylase domain protein 2 in oxygen homeostasis

21 June 2018

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The neuroblast and angioblast chemotaxic factor SDF-1 (CXCL12) expression is briefly up regulated by reactive astrocytes in brain following neonatal hypoxic-ischemic injury

21 June 2018

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21 June 2018

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HIF-2alpha regulates murine hematopoietic development in an erythropoietin-dependent manner

21 June 2018

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Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

21 June 2018

1 reference

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21 June 2018

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21 June 2018

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Nitric oxide prevents cardiovascular disease and determines survival in polyglobulic mice overexpressing erythropoietin

21 June 2018

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Neurons and astrocytes express EPO mRNA: oxygen-sensing mechanisms that involve the redox-state of the brain

21 June 2018

1 reference

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Regulation of the erythropoietin gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3628111

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

21 June 2018

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21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3628111

CXCR4 and CXCL12 expression is increased in the nigro-striatal system of Parkinson's disease.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3628111

PHD2 mutation and congenital erythrocytosis with paraganglioma.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3628111

Disturbance in the HIF-1alpha pathway associated with erythrocytosis: further evidences brought by frameshift and nonsense mutations in the prolyl hydroxylase domain protein 2 (PHD2) gene

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3628111

Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3628111

Excessive erythrocytosis, chronic mountain sickness, and serum cobalt levels

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3628111

HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3628111

Chronic inborn erythrocytosis leads to cardiac dysfunction and premature death in mice overexpressing erythropoietin

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23264599

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2012-08-449181

1 reference

26 July 2017

1 reference

26 July 2017

1 reference