(Q33416776)

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Preliminary evidence for cell membrane amelioration in children with cystic fibrosis by 5-MTHF and vitamin B12 supplementation: a single arm trial

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scholarly article

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Europe PubMed Central

PubMed publication ID

26 July 2017

Preliminary evidence for cell membrane amelioration in children with cystic fibrosis by 5-MTHF and vitamin B12 supplementation: a single arm trial (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

cystic fibrosis

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object named as

Ciro D'Orazio

12

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Oscar Bortolami

object named as

Oscar Bortolami

9

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author name string

Cinzia Scambi

1

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Lucia De Franceschi

2

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Patrizia Guarini

3

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Fabio Poli

4

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Europe PubMed Central

PubMed publication ID

26 July 2017

Angela Siciliano

5

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Patrizia Pattini

6

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Andrea Biondani

7

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Valentina La Verde

8

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Europe PubMed Central

PubMed publication ID

26 July 2017

Francesco Turrini

10

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Franco Carta

11

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Baroukh M Assael

13

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Giovanni Faccini

14

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Europe PubMed Central

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26 July 2017

Lisa M Bambara

15

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Europe PubMed Central

PubMed publication ID

26 July 2017

language of work or name

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publication date

11 March 2009

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

4

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Europe PubMed Central

PubMed publication ID

26 July 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

e4782

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

copyright license

Creative Commons Attribution 4.0 International

11 March 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Markers of oxidative stress in erythrocytes during aging in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Protein/RNA coextraction and small two-dimensional polyacrylamide gel electrophoresis for proteomic/gene expression analysis of renal cancer biopsies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Sick chaperones, cellular stress, and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Regulation of human methylenetetrahydrofolate reductase by phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Acrylamide-agarose copolymers: improved resolution of high molecular mass proteins in two-dimensional gel electrophoresis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Erythrocytes of humans with cystic fibrosis fail to stimulate nitric oxide synthesis in isolated rabbit lungs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

A mathematical model of the folate cycle: new insights into folate homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Analysis of expired air for oxidation products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Role for phospholipid interactions in the trafficking defect of Delta F508-CFTR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Erythrocyte membrane ATP binding cassette (ABC) proteins: MRP1 and CFTR as well as CD39 (ecto-apyrase) involved in RBC ATP transport and elevated blood plasma ATP of cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

A membrane lipid imbalance plays a role in the phenotypic expression of cystic fibrosis in cftr(-/-) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Folate and vitamin B12

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Oral magnesium supplements reduce erythrocyte dehydration in patients with sickle cell disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Regulation of epithelial sodium channels by the cystic fibrosis transmembrane conductance regulator.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Oxygen free radicals and antioxidants in cystic fibrosis: the concept of an oxidant-antioxidant imbalance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Docosahexaenoic acid in red blood cells of patients with X-linked retinitis pigmentosa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

CFTR and outward rectifying chloride channels are distinct proteins with a regulatory relationship

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

CFTR as a cAMP-dependent regulator of sodium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Phosphatidylcholine produced in rat synaptosomes by N-methylation is enriched in polyunsaturated fatty acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Lymphocyte and granulocyte phosphatidylethanolamine N-methyltransferase: properties and activity in cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Kinetic parameters of rubidium transport pathways are normal in cystic fibrosis red cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Increased susceptibility to peroxide-induced haemolysis with normal vitamin E concentrations in cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Abnormal regulation of ion channels in cystic fibrosis epithelia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Calcium and sodium transport processes in patients with cystic fibrosis. I. A specific decrease in Mg2+-dependent, Ca2+-adenosine triphosphatase activity in erythrocyte membranes from cystic fibrosis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

14 July 2018

Altered phospholipid composition and aggregate structure of lung surfactant is associated with impaired lung function in young children with respiratory infections

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004782

21 January 2018

Essential fatty acid deficiency in relation to genotype in patients with cystic fibrosis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004782

21 January 2018

Fatty acid metabolism in cystic fibrosis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004782

21 January 2018

Cystic fibrosis transmembrane conductance regulator in human and mouse red blood cell membranes and its interaction with ecto-apyrase

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004782

21 January 2018

Association of cystic fibrosis with abnormalities in fatty acid metabolism.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004782

21 January 2018

Can 5-methyltetrahydrofolate modify the phospholipid fatty acid pattern in cystic fibrosis pediatric patients?

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004782

21 January 2018

Increased plasma homocysteine and S-adenosylhomocysteine and decreased methionine is associated with altered phosphatidylcholine and phosphatidylethanolamine in cystic fibrosis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004782

21 January 2018

Reduced number of CFTR molecules in erythrocyte plasma membrane of cystic fibrosis patients.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004782

21 January 2018

Rapid, fluorimetric-liquid chromatographic determination of malondialdehyde in biological samples

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004782

21 January 2018

Cellular folate vitamer distribution during and after correction of vitamin B12 deficiency: a case for the methylfolate trap

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004782

21 January 2018

Tetrahydrofolate and 5-methyltetrahydrofolate are folates with high antioxidant activity. Identification of the antioxidant pharmacophore

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004782

21 January 2018

Oxidative stress in cystic fibrosis: dietary and metabolic factors.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004782

21 January 2018

Longitudinal study of oxidative status in 312 cystic fibrosis patients in stable state and during bronchial exacerbation

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004782

21 January 2018

Simultaneous measurement of seven carotenoids, retinol and α-tocopherol in serum by high-performance liquid chromatography

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0004782

21 January 2018

Calculation of red blood cell folate steady state conditions and elimination kinetics after daily supplementation with various folate forms and doses in women of childbearing age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

31 October 2018

Red blood cell folate concentrations increase more after supplementation with [6S]-5-methyltetrahydrofolate than with folic acid in women of childbearing age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

31 October 2018

Increased plasma fatty acid concentrations after respiratory exacerbations are associated with elevated oxidative stress in cystic fibrosis patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

31 October 2018

Antioxidant status in erythrocytes of cystic fibrosis children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652076

31 October 2018

Direct transesterification of all classes of lipids in a one-step reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of complete protein 4.1R deficiency on ion transport properties of murine erythrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term docosahexaenoic acid therapy in a congenic murine model of cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chloride channels in normal and cystic fibrosis human erythrocyte membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acids platelets and oxidative markers following intravenous n-3 fatty acids administration in cystic fibrosis: An open pilot observational study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adult cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered copper status in adult men with cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

K dependence of the Na-K pump is abnormal in erythrocytes from patients with cystic fibrosis and obligate heterozygotes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant free radical activity in cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low concentrations of sodium and magnesium in erythrocytes from cystic fibrosis heterozygotes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free and bound malondialdehyde measured as thiobarbituric acid adduct by HPLC in serum and plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid high-performance liquid chromatographic assay for total homocysteine levels in human serum

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Red blood cells and platelet membrane fatty acids in non-dialyzed and dialyzed uremics

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cystic fibrosis and phosphatidylcholine biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of hemichrome binding to erythrocyte membrane in the generation of band-3 alterations in beta-thalassemia intermedia erythrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Red blood cell cation transports in uraemic anaemia: evidence for an increased K/Cl co-transport activity. Effects of dialysis and erythropoietin treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin E supplementation in cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostanoid biosynthesis in patients with cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered erythrocyte sodium-lithium counter-transport and Na+/K(+)-ATPase activity in cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipid peroxidation and antioxidant defenses in cystic fibrosis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Controlled comparison of L-5-methyltetrahydrofolate versus folic acid for the treatment of hyperhomocysteinemia in hemodialysis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Function and composition of pulmonary surfactant and surfactant-derived fatty acid profiles are altered in young adults with cystic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Folate administration increases n-3 polyunsaturated fatty acids in rat plasma and tissue lipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The deltaF508 mutation in the cystic fibrosis transmembrane conductance regulator alters control of essential fatty acid utilization in epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the effect of low-dose supplementation with L-5-methyltetrahydrofolate or folic acid on plasma homocysteine: a randomized placebo-controlled study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Interaction between MTHFR 677 C→T Genotype and Folate Status Is a Determinant of Coronary Atherosclerosis Risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Folate Deficiency in the Alcoholic—its Relationship to Clinical and Haematological Abnormalities, Liver Disease and Folate Stores

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of variations in dietary fatty acids on the fatty acid composition of erythrocyte phosphatidylcholine and phosphatidylethanolamine in human infants

1 reference

https://pubmed.ncbi.nlm.nih.gov/19277125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0004782

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

2009PLoSO...4.4782S

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

ResearchGate publication ID

0 references

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