(Q33417208)

26 July 2017

title

Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2 (English)

1 reference

26 July 2017

6

Craig W Lindsley

1 reference

26 July 2017

Eric Delpire

1

1 reference

26 July 2017

Emily Days

2

1 reference

26 July 2017

L Michelle Lewis

3

1 reference

26 July 2017

Dehui Mi

4

1 reference

26 July 2017

Kwangho Kim

5

1 reference

26 July 2017

C David Weaver

7

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26 July 2017

language of work or name

English

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publication date

11 March 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

26 July 2017

published in

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26 July 2017

volume

106

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26 July 2017

issue

13

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26 July 2017

page(s)

5383-5388

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The role of cation-dependent chloride transporters in neuropathic pain following spinal cord injury

26 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Allodynia and hyperalgesia in diabetic rats are mediated by GABA and depletion of spinal potassium-chloride co-transporters

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Loose ligation of the sciatic nerve is associated with TrkB receptor-dependent decreases in KCC2 protein levels in the ipsilateral spinal dorsal horn

28 July 2018

1 reference

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A thallium-sensitive, fluorescence-based assay for detecting and characterizing potassium channel modulators in mammalian cells

28 July 2018

1 reference

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Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure-activity analysis, and in vivo efficacy

28 July 2018

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Hyperexcitability and epilepsy associated with disruption of the mouse neuronal-specific K-Cl cotransporter gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Functional comparison of the K+-Cl- cotransporters KCC1 and KCC4.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Deafness and imbalance associated with inactivation of the secretory Na-K-2Cl co-transporter

28 July 2018

1 reference

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Functional characterization of the neuronal-specific K-Cl cotransporter: implications for [K+]o regulation

28 July 2018

1 reference

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Molecular and clinical implications of loop diuretic ototoxicity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Molecular characterization of a putative K-Cl cotransporter in rat brain. A neuronal-specific isoform

28 July 2018

1 reference

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Ototoxicity of loop diuretics.

28 July 2018

1 reference

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Chloride-activated passive potassium transport in human erythrocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

A Simple Method for Derivation of Rate Equations for Enzyme-catalyzed Reactions under the Rapid Equilibrium Assumption or Combined Assumptions of Equilibrium and Steady State

28 July 2018

1 reference

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Bumetanide: Potent New "Loop" Diuretic

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Regulation of cation content and cell volume in hemoglobin erythrocytes from patients with homozygous hemoglobin C disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Structure and function of the red blood cell anion transport protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Kinetics of Cl-dependent K fluxes in hyposmotically swollen low K sheep erythrocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Tonic activation of group I mGluRs modulates inhibitory synaptic strength by regulating KCC2 activity.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Roles of the cation-chloride cotransporters in neurological disease.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Diabetes affects the expression of GABA and potassium chloride cotransporter in the spinal cord: a study in streptozotocin diabetic rats

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Neurogenic role of the depolarizing chloride gradient revealed by global overexpression of KCC2 from the onset of development.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Reduced potassium-chloride co-transporter expression in spinal cord dorsal horn neurons contributes to inflammatory pain hypersensitivity in rats

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Disrupted dentate granule cell chloride regulation enhances synaptic excitability during development of temporal lobe epilepsy

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Small-molecule screen identifies inhibitors of a human intestinal calcium-activated chloride channel.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Mutations in the K+/Cl- cotransporter gene kazachoc (kcc) increase seizure susceptibility in Drosophila.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Cortical neurons lacking KCC2 expression show impaired regulation of intracellular chloride

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Cation-Chloride Cotransporters in Neuronal Communication.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Potassium-coupled chloride cotransport controls intracellular chloride in rat neocortical pyramidal neurons.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

Intracellular Ca2+ and Cl- channel activation in secretory cells.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2654392

31 October 2018

TODAY'S DRUGS. FRUSEMIDE

1 reference

12 December 2020

A chloride dependent K+ flux induced by N-ethylmaleimide in genetically low K+ sheep and goat erythrocytes

1 reference

12 December 2020

Demonstration of a [K+,Cl-]-cotransport system in human red cells by its sensitivity to [(dihydroindenyl)oxy]alkanoic acids: regulation of cell swelling and distinction from the bumetanide-sensitive [Na+,K+,Cl-]-cotransport system

1 reference

12 December 2020

Expression changes of cation chloride cotransporters in the rat spinal cord following intraplantar formalin

1 reference

12 December 2020

Thiol-dependent passive K/Cl transport in sheep red cells: IV. Furosemide inhibition as a function of external Rb+, Na+, and Cl-

1 reference

12 December 2020

Kinetics of DIDS inhibition of swelling-activated K-Cl cotransport in low K sheep erythrocytes

1 reference

12 December 2020

Trans effects of cellular K and Cl on ouabain-resistant Rb(K) influx in low K sheep red bleed cells: Further evidence for asymmetry of K-Cl cotransport

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0812756106

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26 July 2017

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26 July 2017

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