(Q33417762)

English

Panobinostat plus bortezomib and dexamethasone versus placebo plus bortezomib and dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma: a multicentre, randomised, double-blind phase 3 trial

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Panobinostat plus bortezomib and dexamethasone versus placebo plus bortezomib and dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma: a multicentre, randomised, double-blind phase 3 trial (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

phase III clinical trial

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multicenter clinical trial

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1 reference

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Ashraf Elghandour

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Ashraf Elghandour

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Monika Sopala

41

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Hans Salwender

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Enrique M Ocio

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Hareth Nahi

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Javier de la Rubia

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Javier de la Rubia

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Krzysztof Warzocha

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Krzysztof Warzocha

27

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Paolo Corradini

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Paolo Corradini

11

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Athanasios Dimopoulos

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Meletios Athanasios Dimopoulos

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33

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Sagar Lonial

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Europe PubMed Central

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26 July 2017

Hermann Einsele

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Hermann Einsele

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Paul G. Richardson

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Paul G Richardson

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Philippe Moreau

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Philippe Moreau

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Wieslaw Jedrzejczak

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Wieslaw Wiktor Jedrzejczak

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Kwee Yong

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Jamie D Cavenagh

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Jamie D Cavenagh

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Joan Bladé

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Vânia T M Hungria

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Thanyaphong Na Nakorn

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Thanyaphong Na Nakorn

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Noppadol Siritanaratkul

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Noppadol Siritanaratkul

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Robert Schlossman

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Robert L Schlossman

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Lugui Qiu

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Peter Gimsing

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Claudia Corrado

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Claudia Corrado

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Bourras-Rezki Bengoudifa

43

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Bourras-Rezki Bengoudifa

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Florence Binlich

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object named as

Florence Binlich

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Jonathan L Kaufman

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Jonathan L Kaufman

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WenMing Chen

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Jesús San Miguel

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Jesús F San-Miguel

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26 July 2017

4

object named as

Meral Beksac

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Europe PubMed Central

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26 July 2017

author name string

Sung-Soo Yoon

3

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26 July 2017

Andreas Günther

8

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26 July 2017

Suporn Chuncharunee

12

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26 July 2017

Je-Jung Lee

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26 July 2017

Tatiana Shelekhova

15

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26 July 2017

Daryl Tan

17

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Tontanai Numbenjapon

18

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Europe PubMed Central

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26 July 2017

Jian Hou

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Richard LeBlanc

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Stefano Pulini

25

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Darrell White

28

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Ljupco Veskovski

36

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26 July 2017

Sang Kyun Sohn

37

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26 July 2017

Ming-Chung Wang

38

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26 July 2017

Jae Hoon Lee

39

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Europe PubMed Central

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26 July 2017

publication date

18 September 2014

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Europe PubMed Central

PubMed publication ID

26 July 2017

number of pages

12

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Lancet Oncology Commission

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Europe PubMed Central

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26 July 2017

15

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Europe PubMed Central

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26 July 2017

11

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Europe PubMed Central

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26 July 2017

1195-1206

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Europe PubMed Central

PubMed publication ID

26 July 2017

Improved survival in multiple myeloma and the impact of novel therapies

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism of action of proteasome inhibitors and deacetylase inhibitors and the biological basis of synergy in multiple myeloma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Vorinostat or placebo in combination with bortezomib in patients with multiple myeloma (VANTAGE 088): a multicentre, randomised, double-blind study

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Development of the pan-DAC inhibitor panobinostat (LBH589): successes and challenges

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phase II trial of the pan-deacetylase inhibitor panobinostat as a single agent in advanced relapsed/refractory multiple myeloma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

In vitro and in vivo rationale for the triple combination of panobinostat (LBH589) and dexamethasone with either bortezomib or lenalidomide in multiple myeloma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Aggresome induction by proteasome inhibitor bortezomib and alpha-tubulin hyperacetylation by tubulin deacetylase (TDAC) inhibitor LBH589 are synergistic in myeloma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phase Ib study of panobinostat and bortezomib in relapsed or relapsed and refractory multiple myeloma.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

PANORAMA 2: panobinostat in combination with bortezomib and dexamethasone in patients with relapsed and bortezomib-refractory myeloma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A phase 2 study of bortezomib in relapsed, refractory myeloma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Bortezomib or high-dose dexamethasone for relapsed multiple myeloma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Randomized phase III study of pegylated liposomal doxorubicin plus bortezomib compared with bortezomib alone in relapsed or refractory multiple myeloma: combination therapy improves time to progression

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Criteria for evaluating disease response and progression in patients with multiple myeloma treated by high-dose therapy and haemopoietic stem cell transplantation. Myeloma Subcommittee of the EBMT. European Group for Blood and Marrow Transplant

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Subcutaneous versus intravenous administration of bortezomib in patients with relapsed multiple myeloma: a randomised, phase 3, non-inferiority study

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of response endpoints with survival outcomes in multiple myeloma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Efficacy and safety of once-weekly bortezomib in multiple myeloma patients.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

International Myeloma Working Group consensus statement for the management, treatment, and supportive care of patients with myeloma not eligible for standard autologous stem-cell transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

European Myeloma Network recommendations on the evaluation and treatment of newly diagnosed patients with multiple myeloma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phase I study of vorinostat in combination with bortezomib for relapsed and refractory multiple myeloma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Superiority of the triple combination of bortezomib-thalidomide-dexamethasone over the dual combination of thalidomide-dexamethasone in patients with multiple myeloma progressing or relapsing after autologous transplantation: the MMVAR/IFM 2005-04 R

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Lenalidomide plus dexamethasone for relapsed multiple myeloma in North America

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Lenalidomide plus dexamethasone for relapsed or refractory multiple myeloma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone alone for patients with relapsed and refractory multiple myeloma (MM-003): a randomised, open-label, phase 3 trial

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A phase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970440-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S1470-2045(14)70440-1

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

ResearchGate publication ID

0 references

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