(Q33418091)

26 July 2017

title

A phase 1 trial of the Fc-engineered CD19 antibody XmAb5574 (MOR00208) demonstrates safety and preliminary efficacy in relapsed CLL (English)

1 reference

26 July 2017

main subject

phase I clinical trial

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Ian W Flinn

3

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John C. Byrd

10

object named as

John C Byrd

1 reference

26 July 2017

1

Jennifer A Woyach

1 reference

26 July 2017

2

Farrukh Awan

1 reference

26 July 2017

8

Gerard Lozanski

1 reference

26 July 2017

Jesus G Berdeja

4

1 reference

26 July 2017

Elizabeth Wiley

5

1 reference

26 July 2017

Sharmeen Mansoor

6

1 reference

26 July 2017

Ying Huang

7

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26 July 2017

Paul A Foster

9

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26 July 2017

language of work or name

English

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publication date

9 October 2014

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26 July 2017

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26 July 2017

volume

124

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26 July 2017

issue

24

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26 July 2017

page(s)

3553-3560

1 reference

Obinutuzumab (GA101) in relapsed/refractory chronic lymphocytic leukemia: final data from the phase 1/2 GAUGUIN study

26 July 2017

cites work

1 reference

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Ibrutinib antagonizes rituximab-dependent NK cell-mediated cytotoxicity

21 June 2018

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A phase 1 study evaluating the safety and tolerability of otlertuzumab, an anti-CD37 mono-specific ADAPTIR therapeutic protein in chronic lymphocytic leukemia

21 June 2018

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Addition of rituximab to fludarabine and cyclophosphamide in patients with chronic lymphocytic leukaemia: a randomised, open-label, phase 3 trial

21 June 2018

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Ofatumumab as single-agent CD20 immunotherapy in fludarabine-refractory chronic lymphocytic leukemia

21 June 2018

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Dic(17;18)(p11.2;p11.2) is a recurring abnormality in chronic lymphocytic leukaemia associated with aggressive disease

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256907

CD19 targeting of chronic lymphocytic leukemia with a novel Fc-domain-engineered monoclonal antibody

21 June 2018

1 reference

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Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines

21 June 2018

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Engineered antibody Fc variants with enhanced effector function

21 June 2018

1 reference

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Flow cytometric analysis of acute leukemias. Diagnostic utility and critical analysis of data

21 June 2018

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Randomized phase 2 study of fludarabine with concurrent versus sequential treatment with rituximab in symptomatic, untreated patients with B-cell chronic lymphocytic leukemia: results from Cancer and Leukemia Group B 9712 (CALGB 9712).

21 June 2018

1 reference

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Rituximab therapy of patients with B-cell chronic lymphocytic leukemia

21 June 2018

1 reference

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Rituximab dose-escalation trial in chronic lymphocytic leukemia

21 June 2018

1 reference

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Rituximab using a thrice weekly dosing schedule in B-cell chronic lymphocytic leukemia and small lymphocytic lymphoma demonstrates clinical activity and acceptable toxicity

21 June 2018

1 reference

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Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia

21 June 2018

1 reference

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Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia. European Study Group of CAMPATH-1H Treatment in Chronic Lymphocytic Leukemia

21 June 2018

1 reference

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Membrane IgM-induced tyrosine phosphorylation of CD19 requires a CD19 domain that mediates association with components of the B cell antigen receptor complex

21 June 2018

1 reference

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CD19 antigen in leukemia and lymphoma diagnosis and immunotherapy

21 June 2018

1 reference

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Asynchronous antigen expression in B lineage acute lymphoblastic leukemia.

21 June 2018

1 reference

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Potent in vitro and in vivo activity of an Fc-engineered anti-CD19 monoclonal antibody against lymphoma and leukemia

21 June 2018

1 reference

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Revised response criteria for malignant lymphoma

31 October 2018

1 reference

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Select high-risk genetic features predict earlier progression following chemoimmunotherapy with fludarabine and rituximab in chronic lymphocytic leukemia: justification for risk-adapted therapy

31 October 2018

1 reference

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A minor population of splenic dendritic cells expressing CD19 mediates IDO-dependent T cell suppression via type I IFN signaling following B7 ligation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256907

Chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab for relapsed and refractory chronic lymphocytic leukemia

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256907

Addition of rituximab to fludarabine may prolong progression-free survival and overall survival in patients with previously untreated chronic lymphocytic leukemia: an updated retrospective comparative analysis of CALGB 9712 and CALGB 9011.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256907

Obinutuzumab plus Chlorambucil in Patients with CLL and Coexisting Conditions

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4256907

The immunophenotype of 325 adult acute leukemias: relationship to morphologic and molecular classification and proposal for a minimal screening program highly predictive for lineage discrimination

31 October 2018

1 reference

12 December 2020

Standard-dose anti-CD20 antibody rituximab has efficacy in chronic lymphocytic leukaemia: results from a Nordic multicentre study

1 reference

12 December 2020

Pan B‐cell markers are not redundant in analysis of chronic lymphocytic leukemia (CLL)

1 reference

12 December 2020

Regulation of B lymphocyte development and activation by the CD19/CD21/CD81/Leu 13 complex requires the cytoplasmic domain of CD19

1 reference

12 December 2020

10.1182/BLOOD-2014-08-593269

Identifiers

DOI

1 reference

26 July 2017

1 reference

26 July 2017

1 reference