(Q33418094)

26 July 2017

title

Thrombocytopenia impairs host defense in gram-negative pneumonia-derived sepsis in mice (English)

1 reference

26 July 2017

0 references

Gram-negative bacteria

0 references

0 references

1 reference

6

Tom van der Poll

1 reference

26 July 2017

author name string

Sacha F de Stoppelaar

1

1 reference

26 July 2017

Cornelis van 't Veer

2

1 reference

26 July 2017

Theodora A M Claushuis

3

1 reference

26 July 2017

Bregje J A Albersen

4

1 reference

26 July 2017

Joris J T H Roelofs

5

1 reference

26 July 2017

language of work or name

English

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publication date

9 October 2014

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26 July 2017

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26 July 2017

volume

124

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26 July 2017

issue

25

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26 July 2017

page(s)

3781-3790

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Platelet glycoprotein Ib-IX as a regulator of systemic inflammation.

26 July 2017

cites work

1 reference

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Platelets protect from septic shock by inhibiting macrophage-dependent inflammation via the cyclooxygenase 1 signalling pathway

21 June 2018

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Activated platelets enhance IL-10 secretion and reduce TNF-α secretion by monocytes

21 June 2018

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Severe sepsis and septic shock

21 June 2018

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Nucleation of platelets with blood-borne pathogens on Kupffer cells precedes other innate immunity and contributes to bacterial clearance

21 June 2018

1 reference

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Only severe thrombocytopenia results in bleeding and defective thrombus formation in mice.

21 June 2018

1 reference

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Genomic responses in mouse models poorly mimic human inflammatory diseases

21 June 2018

1 reference

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Platelet ITAM signaling is critical for vascular integrity in inflammation

21 June 2018

1 reference

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21 June 2018

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Intravascular neutrophil extracellular traps capture bacteria from the bloodstream during sepsis

21 June 2018

1 reference

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Platelets: key players in vascular inflammation

21 June 2018

1 reference

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Platelets induce apoptosis during sepsis in a contact-dependent manner that is inhibited by GPIIb/IIIa blockade

21 June 2018

1 reference

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Platelets support a protective immune response to LCMV by preventing splenic necrosis

21 June 2018

1 reference

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Disruption of platelet-derived chemokine heteromers prevents neutrophil extravasation in acute lung injury

21 June 2018

1 reference

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Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum

21 June 2018

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21 June 2018

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Risk factors and pathogenic significance of severe sepsis and septic shock in 2286 patients with gram-negative bacteremia

21 June 2018

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21 June 2018

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Platelets in defense against bacterial pathogens

21 June 2018

1 reference

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Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury

21 June 2018

1 reference

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Sepsis alters the megakaryocyte-platelet transcriptional axis resulting in granzyme B-mediated lymphotoxicity.

21 June 2018

1 reference

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Amicus or adversary: platelets in lung biology, acute injury, and inflammation

21 June 2018

1 reference

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Inflammation induces hemorrhage in thrombocytopenia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263985

Thrombocytopenia in septic shock patients--a prospective observational study of incidence, risk factors and correlation with clinical outcome

21 June 2018

1 reference

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Host-pathogen interactions in sepsis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263985

Inflammation, endothelium, and coagulation in sepsis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263985

Platelet-derived exosomes from septic shock patients induce myocardial dysfunction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263985

Role of the extrinsic pathway of blood coagulation in hemostasis and thrombosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263985

Platelet count decline: an early prognostic marker in critically ill patients with prolonged ICU stays

21 June 2018

1 reference

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Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood

21 June 2018

1 reference

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Impact of thrombocytopenia on outcome of patients admitted to ICU for severe community-acquired pneumonia

21 June 2018

1 reference

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Complete reversal of acid-induced acute lung injury by blocking of platelet-neutrophil aggregation

21 June 2018

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Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263985

The active metabolite of Clopidogrel disrupts P2Y12 receptor oligomers and partitions them out of lipid rafts

21 June 2018

1 reference

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Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-alpha production in vivo

21 June 2018

1 reference

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Activated platelets induce Weibel-Palade-body secretion and leukocyte rolling in vivo: role of P-selectin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263985

Platelet microparticles: a transcellular delivery system for RANTES promoting monocyte recruitment on endothelium

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263985

The epidemiology of sepsis in the United States from 1979 through 2000

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263985

Time course of platelet counts in critically ill patients.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263985

Circulating platelet-neutrophil complexes represent a subpopulation of activated neutrophils primed for adhesion, phagocytosis and intracellular killing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263985

Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263985

Protease activated receptor 4 limits bacterial growth and lung pathology during late stage Streptococcus pneumoniae induced pneumonia in mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263985

Beneficial effect of clopidogrel in a mouse model of polymicrobial sepsis.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263985

Platelets support pulmonary recruitment of neutrophils in abdominal sepsis

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263985

Endothelial cell apoptosis induced by bacteria-activated platelets requires caspase-8 and -9 and generation of reactive oxygen species.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263985

Early endotoxin-mediated haemostatic and inflammatory responses in the clopidogrel-treated pig.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263985

Interaction with autologous platelets multiplies interleukin-1 and tumor necrosis factor production in mononuclear cells

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25301709

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Loss of suppression of tumorigenicity 2 (ST2) gene reverses sepsis-induced inhibition of lung host defense in mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25301709

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The role of platelets in sepsis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25301709

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2014-05-573915

1 reference

26 July 2017

1 reference

26 July 2017

1 reference