(Q33418729)

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Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer

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Europe PubMed Central

26 July 2017

Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer (English)

1 reference

Europe PubMed Central

26 July 2017

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22

object named as

Mario Roederer

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Europe PubMed Central

26 July 2017

Steven Rosenberg

4

object named as

Steven A Rosenberg

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26 July 2017

5

object named as

Antonio Tito Fojo

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Europe PubMed Central

26 July 2017

William Douglas Figg, Sr.

16

object named as

William D Figg

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26 July 2017

H. Clifford Lane

19

object named as

H Clifford Lane

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26 July 2017

Liyanage P Perera

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object named as

Liyanage P Perera

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26 July 2017

Thomas Waldmann

23

object named as

Thomas A Waldmann

1 reference

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26 July 2017

author name string

Kevin C Conlon

1

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26 July 2017

Enrico Lugli

2

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26 July 2017

Hugh C Welles

3

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26 July 2017

John C Morris

6

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26 July 2017

Thomas A Fleisher

7

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26 July 2017

Sigrid P Dubois

8

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26 July 2017

Donn M Stewart

10

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26 July 2017

Carolyn K Goldman

11

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26 July 2017

Bonita R Bryant

12

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Europe PubMed Central

26 July 2017

Jean M Decker

13

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26 July 2017

Jing Chen

14

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26 July 2017

Tat'Yana A Worthy

15

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26 July 2017

Cody J Peer

17

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26 July 2017

Michael C Sneller

18

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26 July 2017

Jason L Yovandich

20

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26 July 2017

Stephen P Creekmore

21

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26 July 2017

language of work or name

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publication date

17 November 2014

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Europe PubMed Central

26 July 2017

number of pages

9

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Journal of Clinical Oncology

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26 July 2017

33

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1

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26 July 2017

74-82

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Europe PubMed Central

26 July 2017

IL-2 therapy promotes suppressive ICOS+ Treg expansion in melanoma patients

1 reference

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Cytokine release syndrome after blinatumomab treatment related to abnormal macrophage activation and ameliorated with cytokine-directed therapy.

1 reference

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Chimeric antigen receptor-modified T cells for acute lymphoid leukemia

1 reference

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CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia

1 reference

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21 June 2018

Augmented IL-15Rα expression by CD40 activation is critical in synergistic CD8 T cell-mediated antitumor activity of anti-CD40 antibody with IL-15 in TRAMP-C2 tumors in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

Interleukin-6 in sepsis and capillary leakage syndrome

1 reference

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21 June 2018

IL-15 administered by continuous infusion to rhesus macaques induces massive expansion of CD8+ T effector memory population in peripheral blood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

SPICE: exploration and analysis of post-cytometric complex multivariate datasets

1 reference

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21 June 2018

Transient and persistent effects of IL-15 on lymphocyte homeostasis in nonhuman primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

Coordinate expression and trans presentation of interleukin (IL)-15Ralpha and IL-15 supports natural killer cell and memory CD8+ T cell homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

Role of trans-cellular IL-15 presentation in the activation of NK cell-mediated killing, which leads to enhanced tumor immunosurveillance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

Interleukin-2 and interleukin-15: immunotherapy for cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for immunotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

The interleukin-2 receptor gamma chain: its role in the multiple cytokine receptor complexes and T cell development in XSCID

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

Fas and the art of lymphocyte maintenance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

21 June 2018

Combination therapy of an orthotopic renal cell carcinoma model using intratumoral vector-mediated costimulation and systemic interleukin-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

31 October 2018

Characterization of CD4+CD25+ regulatory T cells in patients treated with high-dose interleukin-2 for metastatic melanoma or renal cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

31 October 2018

Development and proliferation of lymphocytes in mice deficient for both interleukins-2 and -4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4268254

31 October 2018

Treatment of 283 consecutive patients with metastatic melanoma or renal cell cancer using high-dose bolus interleukin 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/25403209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies evaluating the antitumor activity and toxicity of interleukin-15, a new T cell growth factor: comparison with interleukin-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/25403209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-15 Mediates Anti-tumor Effects after Cyclophosphamide Injection of Tumor-Bearing Mice and Enhances Adoptive Immunotherapy: The Potential Role of NK Cell Subpopulations

1 reference

https://pubmed.ncbi.nlm.nih.gov/25403209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: transpresentation of IL-15 by bone marrow-derived cells necessitates expression of IL-15 and IL-15R alpha by the same cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25403209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fueling regulation: IL-2 keeps CD4+ Treg cells fit

1 reference

https://pubmed.ncbi.nlm.nih.gov/25403209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-2 administration alters the CD4+FOXP3+ T-cell pool and tumor trafficking in patients with ovarian carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25403209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1200/JCO.2014.57.3329

1 reference

Europe PubMed Central

26 July 2017

1 reference

Europe PubMed Central

26 July 2017

1 reference

Europe PubMed Central

26 July 2017

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