(Q33425955)

26 July 2017

title

Astrocyte- and endothelial-targeted CCL2 conditional knockout mice: critical tools for studying the pathogenesis of neuroinflammation (English)

1 reference

26 July 2017

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Shujun Ge

1

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26 July 2017

Nivetha Murugesan

series ordinal

2

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26 July 2017

Joel S Pachter

series ordinal

3

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26 July 2017

language of work or name

1 reference

2 April 2009

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Journal of Molecular Neuroscience

26 July 2017

published in

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26 July 2017

volume

39

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26 July 2017

issue

1-2

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26 July 2017

page(s)

269-283

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Chemokines in vascular dysfunction and remodeling.

26 July 2017

cites work

1 reference

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Chemokines as pain mediators and modulators

21 June 2018

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Therapeutic targeting of chemokine signaling in Multiple Sclerosis

21 June 2018

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MCP-1-deficient mice show reduced neuroinflammatory responses and increased peripheral inflammatory responses to peripheral endotoxin insult

21 June 2018

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An engineered monomer of CCL2 has anti-inflammatory properties emphasizing the importance of oligomerization for chemokine activity in vivo.

21 June 2018

1 reference

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Drug delivery to brain tumors

21 June 2018

1 reference

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Glial cross-talk by transmembrane chemokines CX3CL1 and CXCL16.

21 June 2018

1 reference

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Blood-neural barrier: its diversity and coordinated cell-to-cell communication

21 June 2018

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Brain-region-specific astroglial responses in vitro after LPS exposure

21 June 2018

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Increased in vivo activation of microglia and astrocytes in the brains of mice transgenic for an infectious R5 human immunodeficiency virus type 1 provirus and for CD4-specific expression of human cyclin T1 in response to stimulation by lipopolysacc

21 June 2018

1 reference

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Increased systemic and brain cytokine production and neuroinflammation by endotoxin following ethanol treatment

21 June 2018

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New developments in understanding and treating neuroinflammation.

21 June 2018

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Strategies to improve drug delivery across the blood-brain barrier

21 June 2018

1 reference

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Targeting the brain: rationalizing the novel methods of drug delivery to the central nervous system

21 June 2018

1 reference

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Subendothelial heparan sulfate proteoglycans become major L-selectin and monocyte chemoattractant protein-1 ligands upon renal ischemia/reperfusion

21 June 2018

1 reference

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Caveolin-1 regulates expression of junction-associated proteins in brain microvascular endothelial cells

21 June 2018

1 reference

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Induction of chemokine and cytokine genes in astrocytes following infection with Theiler's murine encephalomyelitis virus is mediated by the Toll-like receptor 3.

21 June 2018

1 reference

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Astrocyte heterogeneity revealed by expression of a GFAP-LacZ transgene.

21 June 2018

1 reference

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Astrocyte-endothelial interactions at the blood-brain barrier

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

The blood-brain barrier/neurovascular unit in health and disease

21 June 2018

1 reference

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Overexpression of monocyte chemotactic protein-1/CCL2 in beta-amyloid precursor protein transgenic mice show accelerated diffuse beta-amyloid deposition

21 June 2018

1 reference

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Cell biology of the neurovascular unit: implications for drug delivery across the blood-brain barrier

21 June 2018

1 reference

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Where is the blood-brain barrier ... really?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

MCP-1 and CCR2 contribute to non-lymphocyte-mediated brain disease induced by Fr98 polytropic retrovirus infection in mice: role for astrocytes in retroviral neuropathogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Molecular diversity of astrocytes with implications for neurological disorders

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Identification of the glycosaminoglycan binding site of the CC chemokine, MCP-1: implications for structure and function in vivo.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Culture of murine brain microvascular endothelial cells that maintain expression and cytoskeletal association of tight junction-associated proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

CCL2 transgene expression in the central nervous system directs diffuse infiltration of CD45(high)CD11b(+) monocytes and enhanced Theiler's murine encephalomyelitis virus-induced demyelinating disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Cytokine regulation of MCP-1 expression in brain and retinal microvascular endothelial cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

The blood-brain barrier and its role in immune privilege in the central nervous system

21 June 2018

1 reference

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Regulation and Functional Effects of Monocyte Migration across Human Brain-Derived Endothelial Cells

21 June 2018

1 reference

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Targeting monocyte chemoattractant protein-1 signalling in disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Functional expression of CCR2 by human fetal astrocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Glial cell influence on the human blood-brain barrier

21 June 2018

1 reference

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Endothelial cell laminin isoforms, laminins 8 and 10, play decisive roles in T cell recruitment across the blood-brain barrier in experimental autoimmune encephalomyelitis

21 June 2018

1 reference

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Regulation of the gene encoding the monocyte chemoattractant protein 1 (MCP-1) in the mouse and rat brain in response to circulating LPS and proinflammatory cytokines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Conditional vascular cell adhesion molecule 1 deletion in mice: impaired lymphocyte migration to bone marrow

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Control of chemokine production at the blood-retina barrier

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Determinants of endothelial cell phenotype in venules

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Inflammatory mediators and modulation of blood-brain barrier permeability

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Expression of MCP-1 by reactive astrocytes in demyelinating multiple sclerosis lesions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: an immunohistochemical and in situ hybridization study

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Expression of monocyte chemoattractant protein-1 and other beta-chemokines by resident glia and inflammatory cells in multiple sclerosis lesions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Mouse astrocytes respond to the chemokines MCP-1 and KC, but reverse transcriptase-polymerase chain reaction does not detect mRNA for the KC or new MCP-1 receptor.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Cytokines and adhesion molecules in stroke and related diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Localization of monocyte chemoattractant peptide-1 expression in the central nervous system in experimental autoimmune encephalomyelitis and trauma in the rat.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Induced expression of adhesion molecules following focal brain ischemia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Astrocyte expression of mRNA encoding cytokines IP-10 and JE/MCP-1 in experimental autoimmune encephalomyelitis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

The nomenclature of chemokines.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Controlled recruitment of monocytes and macrophages to specific organs through transgenic expression of monocyte chemoattractant protein-1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Human monocyte chemoattractant protein-1 (MCP-1).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Production and characterization of mouse monoclonal antibodies against human monocyte chemoattractant protein-1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Recombinant human MCP-1/JE induces chemotaxis, calcium flux, and the respiratory burst in human monocytes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

JE/MCP-1: an early-response gene encodes a monocyte-specific cytokine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Stimulus Specific Induction of Monocyte Chemotactic Protein-1 (MCP-1) Gene Expression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Monocyte chemoattractant protein-1 deficiency is protective in a murine stroke model

21 June 2018

1 reference

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The beta chemokines CCL4 and CCL5 enhance adhesion of specific CD4+ T cell subsets to human brain endothelial cells

21 January 2018

1 reference

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https://api.crossref.org/works/10.1007%2FS12031-009-9197-4

A requirement for microglial TLR4 in leukocyte recruitment into brain in response to lipopolysaccharide

21 January 2018

1 reference

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https://api.crossref.org/works/10.1007%2FS12031-009-9197-4

What is the blood-brain barrier (not)?

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Kinetics of inflammatory response of astrocytes induced by TLR 3 and TLR4 ligation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Brain cytokine synthesis induced by an intraparenchymal injection of LPS is reduced in MCP-1-deficient mice prior to leucocyte recruitment

31 October 2018

1 reference

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Expression of MCP-1 in the hippocampus of SHRSP with ischemia-related delayed neuronal death

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Characterization of an improved procedure for the removal of microglia from confluent monolayers of primary astrocytes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Vascular endothelium-selective gene induction by Tie2 promoter/enhancer in the brain and retina of a transgenic rat.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Chronic expression of monocyte chemoattractant protein-1 in the central nervous system causes delayed encephalopathy and impaired microglial function in mice.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

CCL2 and CCL5 mediate leukocyte adhesion in experimental autoimmune encephalomyelitis--an intravital microscopy study.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Preferential activity of Tie2 promoter in arteriolar endothelium.

31 October 2018

1 reference

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The blood-brain barrier and neurotherapeutics

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

How does peripheral lipopolysaccharide induce gene expression in the brain of rats?

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Monocyte chemoattractant protein-1 alters expression of tight junction-associated proteins in brain microvascular endothelial cells

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Induction of beta-chemokine secretion by human brain microvessel endothelial cells via CD40/CD40L interactions.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Caveolin-1 knockdown by small interfering RNA suppresses responses to the chemokine monocyte chemoattractant protein-1 by human astrocytes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Pertussis toxin-induced reversible encephalopathy dependent on monocyte chemoattractant protein-1 overexpression in mice.

31 October 2018

1 reference

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HIV-Tat protein induces oxidative and inflammatory pathways in brain endothelium

31 October 2018

1 reference

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Migration of multiple sclerosis lymphocytes through brain endothelium

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

hGFAP-cre transgenic mice for manipulation of glial and neuronal function in vivo

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Effect of LPS on the permeability of the blood-brain barrier to insulin

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Chemokines and chemotaxis of leukocytes in infectious meningitis

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2903863

Autoimmunity in the brain: the pathogenesis insight from cell biology

31 October 2018

1 reference

12 December 2020

Mice overexpressing chemokine ligand 2 (CCL2) in astrocytes display enhanced nociceptive responses

1 reference

12 December 2020

Transcellular transport of CCL2 across brain microvascular endothelial cells

1 reference

12 December 2020

Investigational C-C chemokine receptor 2 antagonists for the treatment of autoimmune diseases

1 reference

12 December 2020

Inflammatory activation of human brain endothelial cells by hypoxic astrocytes in vitro is mediated by IL-1beta

1 reference

12 December 2020

Characterization of binding sites for chemokines MCP-1 and MIP-1alpha on human brain microvessels

1 reference

12 December 2020

Molecular mechanisms involved in lymphocyte recruitment in inflamed brain microvessels: critical roles for P-selectin glycoprotein ligand-1 and heterotrimeric G(i)-linked receptors

1 reference

12 December 2020

LPS-induced expression of a novel chemokine receptor (L-CCR) in mouse glial cells in vitro and in vivo

1 reference

12 December 2020

Immunoneutralization of chemokines for the prevention and treatment of central nervous system autoimmune disease

1 reference

12 December 2020

Expression of CSF-1, c-fms, and MCP-1 in the central nervous system of rats with experimental allergic encephalomyelitis

1 reference

12 December 2020

Production and function of monocyte chemoattractant protein-1 and other β-chemokines in murine glial cells

1 reference

12 December 2020

Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain

1 reference

12 December 2020

Central nervous system chemokine mRNA accumulation follows initial leukocyte entry at the onset of acute murine experimental autoimmune encephalomyelitis

1 reference

12 December 2020

MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions

1 reference

12 December 2020

Chemokine mRNA expression in the cauda equina of Lewis rats with experimental allergic neuritis

1 reference

12 December 2020

Differential activation of astrocytes by innate and adaptive immune stimuli

1 reference

12 December 2020

Transgenic expression of CCL2 in the central nervous system prevents experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Inflammatory mediators in atherosclerotic vascular disease

1 reference

12 December 2020

Basement membrane proteins in multiple sclerosis-associated inflammatory cuffs: potential role in influx and transport of leukocytes

1 reference

12 December 2020

10.1007/S12031-009-9197-4

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DOI

1 reference

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26 July 2017

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1 reference

26 July 2017

1 reference