(Q33432147)

26 July 2017

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title

Target-based drug discovery: the emerging success of frontal affinity chromatography coupled to mass spectrometry (English)

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26 July 2017

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Enrica Calleri

1

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Caterina Temporini

object named as

Caterina Temporini

series ordinal

2

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author name string

Gabriele Caccialanza

series ordinal

3

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26 July 2017

Gabriella Massolini

series ordinal

4

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26 July 2017

publication date

1 June 2009

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26 July 2017

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26 July 2017

volume

4

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26 July 2017

issue

6

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26 July 2017

page(s)

905-916

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Frontal affinity chromatography for the screening of mixtures

26 July 2017

cites work

1 reference

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Hit and lead generation: beyond high-throughput screening

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Virtual screening and its integration with modern drug design technologies.

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Hit discovery and hit-to-lead approaches

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Affinity selection-mass spectrometry and its emerging application to the high throughput screening of G protein-coupled receptors

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7 January 2021

Application of mass spectrometry technologies for the discovery of low-molecular weight modulators of enzymes and protein-protein interactions

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7 January 2021

Applications of mass spectrometry in early stages of target based drug discovery

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Biochemical applications of mass spectrometry in pharmaceutical drug discovery

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7 January 2021

Affinity selection-mass spectrometry screening techniques for small molecule drug discovery

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7 January 2021

Micro-Scale Frontal Affinity Chromatography with Mass Spectrometric Detection: A New Method for the Screening of Compound Libraries

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Emerging challenges in ligand discovery: new opportunities for chromatographic assay

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7 January 2021

Frontal affinity chromatography-mass spectrometry

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https://api.crossref.org/works/10.1002%2FCMDC.200800436

7 January 2021

Frontal affinity chromatography with MS detection (FAC-MS) in drug discovery

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Frontal affinity chromatography-mass spectrometry assay technology for multiple stages of drug discovery: applications of a chromatographic biosensor

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7 January 2021

Biosensor alternative: frontal affinity chromatography

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https://api.crossref.org/works/10.1002%2FCMDC.200800436

7 January 2021

Development of immobilized membrane-based affinity columns for use in the online characterization of membrane bound proteins and for targeted affinity isolations

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7 January 2021

Affinity monolith chromatography

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https://api.crossref.org/works/10.1002%2FCMDC.200800436

7 January 2021

Applications of silica supports in affinity chromatography

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7 January 2021

Development and characterization of an open tubular column containing immobilized P-glycoprotein for rapid on-line screening for P-glycoprotein substrates

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7 January 2021

Development of an immobilized P-glycoprotein stationary phase for on-line liquid chromatographic determination of drug-binding affinities

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7 January 2021

Syntheses of immobilized G protein-coupled receptor chromatographic stationary phases: characterization of immobilized mu and kappa opioid receptors

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7 January 2021

The synthesis and initial characterization of an immobilized purinergic receptor (P2Y1) liquid chromatography stationary phase for online screening

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7 January 2021

Development of an immobilized GPR17 receptor stationary phase for binding determination using frontal affinity chromatography coupled to mass spectrometry

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7 January 2021

Capillary-scale frontal affinity chromatography/MALDI tandem mass spectrometry using protein-doped monolithic silica columns.

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7 January 2021

Immobilized nicotinic receptor stationary phase for on-line liquid chromatographic determination of drug-receptor affinities

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7 January 2021

Liquid chromatographic studies with immobilized neuronal nicotinic acetylcholine receptor stationary phases: effects of receptor subtypes, pH and ionic strength on drug-receptor interactions.

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7 January 2021

G-protein-coupled receptor chromatographic stationary phases. 2. Ligand-induced conformational mobility in an immobilized beta2-adrenergic receptor.

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7 January 2021

Initial synthesis and characterization of an immobilized heat shock protein 90 column for online determination of binding affinities

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7 January 2021

Protein kinase inhibitors: insights into drug design from structure.

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7 January 2021

Small-molecule inhibitors of PDK1.

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7 January 2021

Frontal affinity chromatography with MS detection of EphB2 tyrosine kinase receptor. 1. Comparison with conventional ELISA.

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7 January 2021

Frontal affinity chromatography with MS detection of EphB2 tyrosine kinase receptor. 2. Identification of small-molecule inhibitors via coupling with virtual screening

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7 January 2021

Global kinase screening. Applications of frontal affinity chromatography coupled to mass spectrometry in drug discovery

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7 January 2021

Automated multiple ligand screening by frontal affinity chromatography-mass spectrometry (FAC-MS).

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7 January 2021

High-throughput screening for enzyme inhibitors using frontal affinity chromatography with liquid chromatography and mass spectrometry

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7 January 2021

The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor

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https://api.crossref.org/works/10.1002%2FCMDC.200800436

7 January 2021

Frontal affinity chromatography combined on-line with mass spectrometry: a tool for the binding study of different epidermal growth factor receptor inhibitors.

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https://api.crossref.org/works/10.1002%2FCMDC.200800436

7 January 2021

Frontal immunoaffinity chromatography with mass spectrometric detection: a method for finding active compounds from traditional Chinese herbs

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https://api.crossref.org/works/10.1002%2FCMDC.200800436

7 January 2021

Critical contribution of nonlinear chromatography to the understanding of retention mechanism in reversed-phase liquid chromatography

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7 January 2021

Identifiers

DOI

10.1002/CMDC.200800436

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26 July 2017

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