(Q33432765)

26 July 2017

title

The transcription factor NFAT5 is required for cyclin expression and cell cycle progression in cells exposed to hypertonic stress (English)

1 reference

26 July 2017

Jose Aramburu

5

0 references

Anjana Rao

3

object named as

Anjana Rao

1 reference

26 July 2017

author name string

Katherine Drews-Elger

1

1 reference

26 July 2017

M Carmen Ortells

2

1 reference

26 July 2017

Cristina López-Rodriguez

4

1 reference

26 July 2017

language of work or name

English

0 references

publication date

21 April 2009

1 reference

26 July 2017

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26 July 2017

volume

4

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26 July 2017

issue

4

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26 July 2017

page(s)

e5245

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Creative Commons Attribution 4.0 International

26 July 2017

copyright license

start time

21 April 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Brx mediates the response of lymphocytes to osmotic stress through the activation of NFAT5

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Osmotically-induced genes are controlled by the transcription factor TonEBP in cultured cardiomyocytes

14 July 2018

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Cyclin A/cdk2 coordinates centrosomal and nuclear mitotic events

14 July 2018

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Intracellular organic osmolytes: function and regulation

14 July 2018

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Analysis of the transcriptional activity of endogenous NFAT5 in primary cells using transgenic NFAT-luciferase reporter mice.

14 July 2018

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Cellular response to hyperosmotic stresses

14 July 2018

1 reference

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Calcineurin-NFATc signaling pathway regulates AQP2 expression in response to calcium signals and osmotic stress

14 July 2018

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Proteomic identification of proteins associated with the osmoregulatory transcription factor TonEBP/OREBP: functional effects of Hsp90 and PARP-1.

14 July 2018

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Hspa4l-deficient mice display increased incidence of male infertility and hydronephrosis development

14 July 2018

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Regulation of the hypertonic stress response and other cellular functions by the Rel-like transcription factor NFAT5.

14 July 2018

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Mre11-Rad50-Nbs1 complex is activated by hypertonicity.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Congenital progressive hydronephrosis (cph) is caused by an S256L mutation in aquaporin-2 that affects its phosphorylation and apical membrane accumulation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Transgenic mice expressing dominant-negative osmotic-response element-binding protein (OREBP) in lens exhibit fiber cell elongation defect associated with increased DNA breaks

14 July 2018

1 reference

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Hypertonic stress response

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Gadd45 proteins induce G2/M arrest and modulate apoptosis in kidney cells exposed to hyperosmotic stress

14 July 2018

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NFAT5/TonEBP mutant mice define osmotic stress as a critical feature of the lymphoid microenvironment

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Cyclin B1 depletion inhibits proliferation and induces apoptosis in human tumor cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

ATM, a DNA damage-inducible kinase, contributes to activation by high NaCl of the transcription factor TonEBP/OREBP.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Expression of taurine transporter is regulated through the TonE (tonicity-responsive element)/TonEBP (TonE-binding protein) pathway and contributes to cytoprotection in HepG2 cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Regulation of expression of the stress response gene, Osp94: identification of the tonicity response element and intracellular signalling pathways

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Hyperosmolar non-ketotic diabetic syndrome associated with rhabdomyolysis and acute renal failure: a case report and review of literature

14 July 2018

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Loss of NFAT5 results in renal atrophy and lack of tonicity-responsive gene expression

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Transcription factor tonicity-responsive enhancer-binding protein (TonEBP) which transactivates osmoprotective genes is expressed and upregulated following acute systemic hypertonicity in neurons in brain

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Fyn and p38 signaling are both required for maximal hypertonic activation of the osmotic response element-binding protein/tonicity-responsive enhancer-binding protein (OREBP/TonEBP)

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Targeted disruption of hsp70.1 sensitizes to osmotic stress

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

TonEBP/NFAT5 stimulates transcription of HSP70 in response to hypertonicity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

A DNA vector-based RNAi technology to suppress gene expression in mammalian cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Bridging the NFAT and NF-kappaB families: NFAT5 dimerization regulates cytokine gene transcription in response to osmotic stress

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Generation and phenotype of mice harboring a nonsense mutation in the V2 vasopressin receptor gene

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

The TonE/TonEBP pathway mediates tonicity-responsive regulation of UT-A urea transporter expression

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

The management of extreme hypernatraemia secondary to salt poisoning in an infant

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Severely impaired urinary concentrating ability in transgenic mice lacking aquaporin-1 water channels

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Adipsic hypernatremia syndrome in infancy.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Targeted disruption of the MHC class II Aa gene in C57BL/6 mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Tumor spectrum analysis in p53-mutant mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Prevention and management of hypernatremic dehydration in breast-fed infants

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

The cyclosporin-sensitive transcription factor NFATp is expressed in several classes of cells in the immune system

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Living with water stress: evolution of osmolyte systems

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

Excessive hypernatremia in a patient with renal amyloid disease.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667631

The osmoprotective function of the NFAT5 transcription factor in T cell development and activation

14 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0005245

Osmotic response element-binding protein (OREBP) is an essential regulator of the urine concentrating mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0005245

Differential cellular distribution of tonicity-induced expression of transcription factor TonEBP in the rat brain following prolonged systemic hypertonicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0005245

The NFAT1 transcription factor is a repressor of cyclin A2 gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0005245

The kinases aurora B and mTOR regulate the G1-S cell cycle progression of T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0005245

TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0005245

A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0005245

Cytometric assessment of histone H2AX phosphorylation: a reporter of DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0005245

c-Myb contributes to G2/M cell cycle transition in human hematopoietic cells by direct regulation of cyclin B1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0005245

Degradation of NFAT5, a transcriptional regulator of osmotic stress-related genes, is a critical event for doxorubicin-induced cytotoxicity in cardiac myocytes

21 January 2018

1 reference

12 December 2020

NFATC2 transcription factor regulates cell cycle progression during lymphocyte activation: evidence of its involvement in the control of cyclin gene expression

1 reference

12 December 2020

Reversible vasopressin deficiency in severe hypernatremia

1 reference

12 December 2020

Nonketotic hyperosmolar coma in a patient with type 1 diabetes-related diabetic nephropathy: case report

1 reference

12 December 2020

A combinatorial role for NFAT5 in both myoblast migration and differentiation during skeletal muscle myogenesis

1 reference

12 December 2020

Protection of Renal Inner Medullary Epithelial Cells from Apoptosis by Hypertonic Stress-induced p53 Activation

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0005245

Identifiers

DOI

1 reference

26 July 2017

0 references

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26 July 2017

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