(Q33440652)

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The Pathway Less Traveled: Moving from Candidate Genes to Candidate Pathways in the Analysis of Genome-Wide Data from Large Scale Pharmacogenetic Association Studies

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

The Pathway Less Traveled: Moving from Candidate Genes to Candidate Pathways in the Analysis of Genome-Wide Data from Large Scale Pharmacogenetic Association Studies (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

genome-wide association study

0 references

author name string

R A Wilke

1

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

R K Mareedu

2

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

J H Moore

3

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

publication date

1 January 2008

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Current Pharmacogenomics and Personalized Medicine: the international journal for expert reviews in pharmacogenomics

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

150-159

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence

1 reference

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21 June 2018

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

1 reference

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21 June 2018

PharmGKB: a logical home for knowledge relating genotype to drug response phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676730

21 June 2018

Pharmacodynamic of cyclooxygenase inhibitors in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676730

21 June 2018

Cardiovascular risk and inhibition of cyclooxygenase: a systematic review of the observational studies of selective and nonselective inhibitors of cyclooxygenase 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676730

21 June 2018

Dissecting trait heterogeneity: a comparison of three clustering methods applied to genotypic data

1 reference

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21 June 2018

Clinical implications of pharmacogenomics of statin treatment

1 reference

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Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial

1 reference

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Aspirin for the primary prevention of cardiovascular events in women and men: a sex-specific meta-analysis of randomized controlled trials

1 reference

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The Gene Ontology (GO) project in 2006

1 reference

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Drug insight: cyclo-oxygenase 2 inhibitors and cardiovascular risk--where are we now?

1 reference

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21 June 2018

Combinatorial pharmacogenetics

1 reference

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Regulation of fatty acid synthesis by farnesyl pyrophosphate

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Genetics, statistics and human disease: analytical retooling for complexity

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The Ubiquitous Nature of Epistasis in Determining Susceptibility to Common Human Diseases

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21 June 2018

Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors

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21 June 2018

Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm (ASCOT-LLA): a multicentre ra

1 reference

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21 June 2018

Statin-associated myopathy

1 reference

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21 June 2018

Guidelines for lowering lipids to reduce coronary artery disease risk: a comparison of rosuvastatin with atorvastatin, pravastatin, and simvastatin for achieving lipid-lowering goals

1 reference

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Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676730

21 June 2018

PharmGKB: the Pharmacogenetics Knowledge Base

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676730

21 June 2018

A high level of cyclooxygenase-2 inhibitor selectivity is associated with a reduced interference of platelet cyclooxygenase-1 inactivation by aspirin

1 reference

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Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer

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21 June 2018

Low-dose aspirin and vitamin E in people at cardiovascular risk: a randomised trial in general practice. Collaborative Group of the Primary Prevention Project

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676730

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Gene ontology: tool for the unification of biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676730

21 June 2018

KEGG: Kyoto Encyclopedia of Genes and Genomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676730

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Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study

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Lipoprotein changes and reduction in the incidence of major coronary heart disease events in the Scandinavian Simvastatin Survival Study (4S)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676730

21 June 2018

A database for post-genome analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676730

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Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676730

21 June 2018

1 reference

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31 October 2018

Genome-wide association. Closing the net on common disease genes

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A common genetic variant is associated with adult and childhood obesity

1 reference

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31 October 2018

Rofecoxib regulates the expression of genes related to the matrix metalloproteinase pathway in humans: implication for the adverse effects of cyclooxygenase-2 inhibitors.

1 reference

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31 October 2018

Visual analysis of statistical results from microarray studies of human breast cancer

2 references

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31 October 2018

https://pubmed.ncbi.nlm.nih.gov/19421424

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotypic predictors of response to simvastatin therapy among African-Americans and Caucasians: the Cholesterol and Pharmacogenetics (CAP) Study

1 reference

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Heart disease and stroke statistics--2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee

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Relative impact of CYP3A genotype and concomitant medication on the severity of atorvastatin-induced muscle damage

1 reference

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Exploratory visual analysis of pharmacogenomic results.

1 reference

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Pharmacogenetic study of statin therapy and cholesterol reduction

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A polymorphism in the cyclooxygenase 2 gene as an inherited protective factor against myocardial infarction and stroke

1 reference

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Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trial

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Interpreting Results of Large-Scale Genetic Association Studies

1 reference

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A global view of epistasis

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The Challenges of Whole-Genome Approaches to Common Diseases

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31 October 2018

Problems with Genome-Wide Association Studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/19421424

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Effects of fluvastatin on coronary atherosclerosis in patients with mild to moderate cholesterol elevations (Lipoprotein and Coronary Atherosclerosis Study [LCAS])

1 reference

https://pubmed.ncbi.nlm.nih.gov/19421424

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based on heuristic

inferred from PubMed ID database lookup

Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19421424

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Problems with genome-wide association studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/19421424

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2174/1875692110806030150

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

ResearchGate publication ID

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