(Q36303810)

13 August 2017

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title

Combinatorial pharmacogenetics (English)

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13 August 2017

3

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13 August 2017

David M Reif

2

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author name string

Russell A Wilke

series ordinal

1

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13 August 2017

1 November 2005

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Nature Reviews Drug Discovery

13 August 2017

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13 August 2017

4

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13 August 2017

911-918

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13 August 2017

11

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https://scigraph.springernature.com/pub.10.1038/nrd1874

13 August 2017

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cites work

Initial sequencing and analysis of the human genome

1 reference

The Sequence of the Human Genome

21 January 2018

1 reference

Pharmacogenetics: an opportunity for a safer and more efficient pharmacotherapy

21 January 2018

1 reference

HFE based re-evaluation of heterozygous hemochromatosis

21 January 2018

1 reference

Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy

21 January 2018

1 reference

Relative impact of covariates in prescribing warfarin according to CYP2C9 genotype

21 January 2018

1 reference

Influence of CYP2C9 and CYP2C19 genetic polymorphisms on warfarin maintenance dose and metabolic clearance.

21 January 2018

1 reference

Warfarin sensitivity related to CYP2C9, CYP3A5, ABCB1 (MDR1) and other factors.

21 January 2018

1 reference

Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response

21 January 2018

1 reference

The legacy of pharmacogenetics and potential applications.

21 January 2018

1 reference

Pharmacogenetics and enzyme induction/inhibition properties of antiepileptic drugs

21 January 2018

1 reference

Dosage recommendation of phenytoin for patients with epilepsy with different CYP2C9/CYP2C19 polymorphisms

21 January 2018

1 reference

Genetic polymorphism of cytochrome P450 2C9 in diphenylhydantoin-induced cutaneous adverse drug reactions

21 January 2018

1 reference

Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes

21 January 2018

1 reference

UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity

21 January 2018

1 reference

Effects of fibrates on metabolism of statins in human hepatocytes

21 January 2018

1 reference

Mechanistic studies on metabolic interactions between gemfibrozil and statins

21 January 2018

1 reference

Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics

21 January 2018

1 reference

Evidence for inverse effects of OATP-C (SLC21A6) 5 and 1b haplotypes on pravastatin kinetics

21 January 2018

1 reference

The effect of gemfibrozil on the pharmacokinetics of rosuvastatin

21 January 2018

1 reference

Controversy surrounding the safety of cerivastatin

21 January 2018

1 reference

Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug inter

21 January 2018

1 reference

Relative impact of CYP3A genotype and concomitant medication on the severity of atorvastatin-induced muscle damage

21 January 2018

1 reference

Association of pharmacokinetic (CYP2C9) and pharmacodynamic (factors II, VII, IX, and X; proteins S and C; and gamma-glutamyl carboxylase) gene variants with warfarin sensitivity

21 January 2018

1 reference

Identification of the gene for vitamin K epoxide reductase

21 January 2018

1 reference

Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2

21 January 2018

1 reference

The Ubiquitous Nature of Epistasis in Determining Susceptibility to Common Human Diseases

21 January 2018

1 reference

The Challenges of Whole-Genome Approaches to Common Diseases

21 January 2018

1 reference

Traversing the conceptual divide between biological and statistical epistasis: systems biology and a more modern synthesis

21 January 2018

1 reference

A global view of epistasis

21 January 2018

1 reference

The risk of determining risk with multivariable models

21 January 2018

1 reference

A simulation study of the number of events per variable in logistic regression analysis

21 January 2018

1 reference

Genetics, statistics and human disease: analytical retooling for complexity

21 January 2018

1 reference

Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer

21 January 2018

1 reference

Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions.

21 January 2018

1 reference

Power of multifactor dimensionality reduction for detecting gene-gene interactions in the presence of genotyping error, missing data, phenocopy, and genetic heterogeneity

21 January 2018

1 reference

Computational analysis of gene-gene interactions using multifactor dimensionality reduction

21 January 2018

1 reference

An application of conditional logistic regression and multifactor dimensionality reduction for detecting gene-gene interactions on risk of myocardial infarction: the importance of model validation

21 January 2018

1 reference

Reporting of model validation procedures in human studies of genetic interactions

21 January 2018

1 reference

Renin-angiotensin system gene polymorphisms and atrial fibrillation

21 January 2018

1 reference

Multifactor-dimensionality reduction shows a two-locus interaction associated with Type 2 diabetes mellitus.

21 January 2018

1 reference

Susceptibility and modifier genes in Portuguese transthyretin V30M amyloid polyneuropathy: complexity in a single-gene disease

21 January 2018

1 reference

MDR and PRP: A Comparison of Methods for High-Order Genotype-Phenotype Associations

21 January 2018

1 reference

New strategies for identifying gene-gene interactions in hypertension

21 January 2018

1 reference

Embryonic-endometrial interactions at implantation in humans.

21 January 2018

1 reference

An association study of the N-methyl-D-aspartate receptor NR1 subunit gene (GRIN1) and NR2B subunit gene (GRIN2B) in schizophrenia with universal DNA microarray

21 January 2018

1 reference

Trimming, weighting, and grouping SNPs in human case-control association studies

21 January 2018

1 reference

Detecting epistatic interactions contributing to quantitative traits

21 January 2018

1 reference

A flexible computational framework for detecting, characterizing, and interpreting statistical patterns of epistasis in genetic studies of human disease susceptibility

21 January 2018

1 reference

Data mining in bioinformatics using Weka

21 January 2018

1 reference

Cytochrome P450 gene-based drug prescribing and factors impacting translation into routine clinical practice

21 January 2018

1 reference

31 March 2020

1 reference

Use of pharmacogenetics and clinical factors to predict the maintenance dose of warfarin.

31 March 2020

1 reference

Elimination of phenytoin in toxic overdose

31 March 2020

1 reference

Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4'-hydroxylation

31 March 2020

1 reference

Development and validation of a high-performance liquid chromatography tandem mass spectrometry assay for atorvastatin, ortho-hydroxy atorvastatin, and para-hydroxy atorvastatin in human, dog, and rat plasma

31 March 2020

1 reference

Quantitation of the acid and lactone forms of atorvastatin and its biotransformation products in human serum by high-performance liquid chromatography with electrospray tandem mass spectrometry

31 March 2020

1 reference

Genomics and drug toxicity

31 March 2020

1 reference

The journey to personalized medicine

31 March 2020

1 reference

Marshfield Clinic Personalized Medicine Research Project (PMRP): design, methods and recruitment for a large population-based biobank

31 March 2020

1 reference

Pacific Symposium on Biocomputing--computational approaches for pharmacogenomics

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRD1874

1 reference

13 August 2017

1 reference

PubMed ID

16264434