(Q33470005)

27 July 2017

title

Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells (English)

1 reference

27 July 2017

1 reference

Eileen Looby

1

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27 July 2017

Mohamed M M Abdel-Latif

2

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27 July 2017

Veronica Athié-Morales

3

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27 July 2017

Shane Duggan

4

1 reference

27 July 2017

Aideen Long

5

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27 July 2017

Dermot Kelleher

6

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27 July 2017

language of work or name

English

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publication date

17 June 2009

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27 July 2017

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27 July 2017

volume

9

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27 July 2017

page(s)

190

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COX-2 induction by unconjugated bile acids involves reactive oxygen species-mediated signalling pathways in Barrett's oesophagus and oesophageal adenocarcinoma

27 July 2017

cites work

1 reference

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The duration of ERK1/2 activity determines the activation of c-Fos and Fra-1 and the composition and quantitative transcriptional output of AP-1.

21 June 2018

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Differences in ERK activation in squamous mucosa in patients who have gastroesophageal reflux disease with and without Barrett's esophagus

21 June 2018

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NF-kappaB activation in esophageal adenocarcinoma: relationship to Barrett's metaplasia, survival, and response to neoadjuvant chemoradiotherapy

21 June 2018

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AP-1: a double-edged sword in tumorigenesis

21 June 2018

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Elevated ERK-MAP kinase activity protects the FOS family member FRA-1 against proteasomal degradation in colon carcinoma cells

21 June 2018

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Bile Acid Regulation of C/EBPβ, CREB, and c-Jun Function, via the Extracellular Signal-Regulated Kinase and c-Jun NH2-Terminal Kinase Pathways, Modulates the Apoptotic Response of Hepatocytes

21 June 2018

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Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate

21 June 2018

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Deoxycholic acid causes DNA damage in colonic cells with subsequent induction of caspases, COX-2 promoter activity and the transcription factors NF-kB and AP-1.

21 June 2018

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AP-1 as a regulator of cell life and death

21 June 2018

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The role of bile acids in carcinogenesis

21 June 2018

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21 June 2018

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21 June 2018

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Activator protein-1 transcription factor mediates bombesin-stimulated cyclooxygenase-2 expression in intestinal epithelial cells

21 June 2018

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Posttranscriptional regulation of cyclooxygenase-2 in rat intestinal epithelial cells

21 June 2018

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Activation and role of mitogen-activated protein kinases in deoxycholic acid-induced apoptosis

21 June 2018

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Aspirin induces apoptosis through mitochondrial cytochrome c release

21 June 2018

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Specificity and mechanism of action of some commonly used protein kinase inhibitors

21 June 2018

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Cell cycle-dependent variations in c-Jun and JunB phosphorylation: a role in the control of cyclin D1 expression.

21 June 2018

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The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade

21 June 2018

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Epidermal growth factor (EGF) suppresses staurosporine-induced apoptosis by inducing mcl-1 via the mitogen-activated protein kinase pathway

21 June 2018

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Cyclooxygenase 2 expression in Barrett's esophagus and adenocarcinoma: Ex vivo induction by bile salts and acid exposure

21 June 2018

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Activation of the promoters of genes associated with DNA damage, oxidative stress, ER stress and protein malfolding by the bile salt, deoxycholate

21 June 2018

1 reference

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Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion

21 June 2018

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Dietary fat and carcinogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704223

Sustained MAP kinase activation is required for the expression of cyclin D1, p21Cip1 and a subset of AP-1 proteins in CCL39 cells

21 June 2018

1 reference

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Toxic bile acids in gastro-oesophageal reflux disease: influence of gastric acidity

21 June 2018

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The repertoire of fos and jun proteins expressed during the G1 phase of the cell cycle is determined by the duration of mitogen-activated protein kinase activation

21 June 2018

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Hyperexpression of mitogen-activated protein kinase in human breast cancer

21 June 2018

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AP-1 function and regulation

21 June 2018

1 reference

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Transformation by ras modifies AP1 composition and activity

21 June 2018

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Variations in Jun and Fos protein expression and AP-1 activity in cycling, resting and stimulated fibroblasts

21 June 2018

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Effect of amount and types of dietary fat on intestinal bacterial 7 alpha-dehydroxylase and phosphatidylinositol-specific phospholipase C and colonic mucosal diacylglycerol kinase and PKC activities during stages of colon tumor promotion.

21 June 2018

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JunB differs from c-Jun in its DNA-binding and dimerization domains, and represses c-Jun by formation of inactive heterodimers

21 June 2018

1 reference

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Characterization of cell lines established from human gastric-esophageal adenocarcinomas. Biologic phenotype and invasion potential

21 June 2018

1 reference

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Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704223

Cellular proliferation and activation of NF kappa B are induced by autocrine production of tumor necrosis factor alpha in the human T lymphoma line HuT 78.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704223

Constitutive activation of mitogen-activated protein (MAP) kinases in human renal cell carcinoma.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704223

The regulation of AP-1 activity by mitogen-activated protein kinases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704223

FcϵRI-mediated Induction of Nuclear Factor of Activated T-cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704223

Role of bile acids in colorectal carcinogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704223

Mixed reflux of gastric and duodenal juices is more harmful to the esophagus than gastric juice alone. The need for surgical therapy re-emphasized

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704223

The Roles of Bile Acids During the Process of Normal Fat and Cholesterol Absorption

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704223

Lytic effects of mixed micelles of fatty acids and bile acids

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704223

Ursodeoxycholic acid inhibits interleukin 1 beta [corrected] and deoxycholic acid-induced activation of NF-kappaB and AP-1 in human colon cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704223

Sustained IL-12 signaling is required for Th1 development

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704223

The bile acid deoxycholic acid (DCA) at neutral pH activates NF-kappaB and induces IL-8 expression in oesophageal cells in vitro

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704223

Expression of apoptosis-related proteins in Barrett's metaplasia-dysplasia-carcinoma sequence: a switch to a more resistant phenotype.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704223

Role of mitochondrial complexes I and II, reactive oxygen species and arachidonic acid metabolism in deoxycholate-induced apoptosis

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704223

Duodenal reflux induces cyclooxygenase-2 in the esophageal mucosa of rats: evidence for involvement of bile acids

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704223

Reflux-induced apoptosis of the esophageal mucosa is inhibited in Barrett's epithelium.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704223

Diet and excretion of bile acids.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704223

Implication of duodenogastric reflux in the pathogenesis of Barrett's oesophagus

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704223

31 October 2018

1 reference

12 December 2020

Fecal profiles of anaerobic microflora of large bowel cancer patients and patients with nonhereditary large bowel polyps

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Lipid esterification and secretion by the mouse intestine in organ culture

1 reference

12 December 2020

Expression and regulation of cyclooxygenase-2 in rat microglia

1 reference

12 December 2020

Dihydroxy bile acids activate the transcription of cyclooxygenase-2

1 reference

12 December 2020

Assessment of combined bile acid and pH profiles using an automated sampling device in gastro-oesophageal reflux disease

1 reference

12 December 2020

Different bile acids exhibit distinct biological effects: the tumor promoter deoxycholic acid induces apoptosis and the chemopreventive agent ursodeoxycholic acid inhibits cell proliferation

1 reference

12 December 2020

p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes

1 reference

12 December 2020

Cyclooxygenase-2 expression in human esophageal carcinoma

1 reference

12 December 2020

Bile acid-induced activation of activator protein-1 requires both extracellular signal-regulated kinase and protein kinase C signaling

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12 December 2020

Identifiers

DOI

10.1186/1471-2407-9-190

1 reference

Dimensions Publication ID

27 July 2017

0 references

1 reference

27 July 2017

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