(Q33477562)

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Quantitative production of compound I from a cytochrome P450 enzyme at low temperatures. Kinetics, activation parameters, and kinetic isotope effects for oxidation of benzyl alcohol

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Europe PubMed Central

PubMed publication ID

27 July 2017

Quantitative production of compound I from a cytochrome P450 enzyme at low temperatures. Kinetics, activation parameters, and kinetic isotope effects for oxidation of benzyl alcohol (English)

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

author name string

Qin Wang

1

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Xin Sheng

2

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

John H Horner

3

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Martin Newcomb

4

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

language of work or name

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publication date

1 August 2009

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Europe PubMed Central

PubMed publication ID

27 July 2017

Journal of the American Chemical Society

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Europe PubMed Central

PubMed publication ID

27 July 2017

131

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Europe PubMed Central

PubMed publication ID

27 July 2017

30

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

10629-10636

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Kinetics of oxidation of benzphetamine by compounds I of cytochrome P450 2B4 and its mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Highly reactive porphyrin-iron-oxo derivatives produced by photolyses of metastable porphyrin-iron(IV) diperchlorates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Kinetic isotope effects in hydroxylation reactions effected by cytochrome P450 compounds I implicate multiple electrophilic oxidants for P450-catalyzed oxidations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Spectra and kinetic studies of the compound I derivative of cytochrome P450 119.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Tunneling in C-H oxidation reactions by an oxoiron(IV) porphyrin radical cation: direct measurements of very large H/D kinetic isotope effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

X-ray absorption spectroscopic characterization of a cytochrome P450 compound II derivative

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Cytochrome p450 and chemical toxicology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Photochemical production of a highly reactive porphyrin-iron-oxo species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Kinetics of two-electron oxidations by the compound I derivative of chloroperoxidase, a model for cytochrome P450 oxidants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Cytochrome p450 compound I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Cytochrome P450 pharmacogenetics and cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

The status of high-valent metal oxo complexes in the P450 cytochromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Kinetic study of the hydrogen abstraction reaction of the benzotriazole-N-oxyl radical (BTNO) with H-donor substrates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Photochemical generation of a highly reactive iron-oxo intermediate. A true iron(V)-oxo species?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Highly reactive electrophilic oxidants in cytochrome P450 catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Freeze-quenched iron-oxo intermediates in cytochromes P450.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Understanding breast cancer risk -- where do we stand in 2005?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Formation of compound I by photo-oxidation of compound II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Hydroxylation by the hydroperoxy-iron species in cytochrome P450 enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Multiple mechanisms and multiple oxidants in P450-catalyzed hydroxylations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Reactions of methane monooxygenase intermediate Q with derivatized methanes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Heme-Containing Oxygenases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Understanding thermostability in cytochrome P450 by combinatorial mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Effects of a thiolate axial ligand on the pi-->pi* electronic states of oxoferryl porphyrins: a study of the optical and resonance Raman spectra of compounds I and II of chloroperoxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Characterization of a cytochrome P450 from the acidothermophilic archaea Sulfolobus solfataricus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

The human hepatic cytochromes P450 involved in drug metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Highly purified cytochrome P-450 from liver microsomal membranes: recent studies on the mechanism of catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Mechanistic studies with purified components of the liver microsomal hydroxylation system: spectral intermediates in reaction of cytochrome P-450 with peroxy compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Studies on hydroperoxide-dependent substrate hydroxylation by purified liver microsomal cytochrome P-450

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

21 June 2018

Characterization of the peroxidase activity of CYP119, a thermostable P450 from Sulfolobus acidocaldarius.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

31 October 2018

Kinetic studies of reactions of iron(IV)-oxo porphyrin radical cations with organic reductants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

31 October 2018

Spectroscopic characterization of the iron-oxo intermediate in cytochrome P450.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

31 October 2018

Reaction of ferric cytochrome P450cam with peracids: kinetic characterization of intermediates on the reaction pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

31 October 2018

Substrate modulation of the properties and reactivity of the oxy-ferrous and hydroperoxo-ferric intermediates of cytochrome P450cam as shown by cryoreduction-EPR/ENDOR spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

31 October 2018

Enhanced electron transfer and lauric acid hydroxylation by site-directed mutagenesis of CYP119.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

31 October 2018

Kinetic characterization of compound I formation in the thermostable cytochrome P450 CYP119.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

31 October 2018

Hydroxylation of camphor by reduced oxy-cytochrome P450cam: mechanistic implications of EPR and ENDOR studies of catalytic intermediates in native and mutant enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

31 October 2018

Large Kinetic Isotope Effects in Methane Oxidation Catalyzed by Methane Monooxygenase: Evidence for C−H Bond Cleavage in a Reaction Cycle Intermediate†

1 reference

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31 October 2018

Cryotrapped Reaction Intermediates of Cytochrome P450 Studied by Radiolytic Reduction with Phosphorus-32

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737099

10 December 2018

Synthesis of Peroxynitrite in a Two-Phase System Using Isoamyl Nitrite and Hydrogen Peroxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/19572732

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxygen activation by cytochrome p450: a thermodynamic analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19572732

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intermediates in the reaction of substrate-free cytochrome P450cam with peroxy acetic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/19572732

12 December 2020

based on heuristic

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Peroxynitrite reaction with heme proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/19572732

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EPR detection and characterization of lignin peroxidase porphyrin pi-cation radical

1 reference

https://pubmed.ncbi.nlm.nih.gov/19572732

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation parameters for cyclohexene oxygenation by an oxoiron(IV) porphyrin pi-cation radical complex: entropy control of an allylic hydroxylation reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/19572732

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for compound I formation in the reaction of cytochrome P450cam with m-chloroperbenzoic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/19572732

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spectrum of chloroperoxidase compound I

1 reference

https://pubmed.ncbi.nlm.nih.gov/19572732

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JA9031105

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Europe PubMed Central

PubMed publication ID

27 July 2017

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27 July 2017

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Europe PubMed Central

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27 July 2017

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