(Q33504867)

27 July 2017

The plasminogen activation system enhances brain and heart invasion in murine relapsing fever borreliosis (English)

1 reference

relapsing fever borreliosis

27 July 2017

1 reference

1 reference

4

T H Bugge

1 reference

27 July 2017

J A Gebbia

1

1 reference

27 July 2017

J C Monco

series ordinal

2

1 reference

27 July 2017

J L Degen

series ordinal

3

1 reference

27 July 2017

J L Benach

series ordinal

5

1 reference

27 July 2017

language of work or name

English

0 references

publication date

1 January 1999

1 reference

Journal of Clinical Investigation

27 July 2017

1 reference

27 July 2017

103

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27 July 2017

1

1 reference

27 July 2017

81-87

1 reference

Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice

27 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Neuroborreliosis during relapsing fever: review of the clinical manifestations, pathology, and treatment of infections in humans and experimental animals.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

The spirochete Borrelia crocidurae causes erythrocyte rosetting during relapsing fever

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Growth and dissemination of Lewis lung carcinoma in plasminogen-deficient mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Neuronal death in the central nervous system demonstrates a non-fibrin substrate for plasmin

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Immunologic and genetic analyses of VmpA of a neurotropic strain of Borrelia turicatae

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Plasminogen is required for efficient dissemination of B. burgdorferi in ticks and for enhancement of spirochetemia in mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

A mouse model of Borrelia meningitis after intradermal injection.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Antigenic variation in Lyme disease borreliae by promiscuous recombination of VMP-like sequence cassettes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Impaired arterial neointima formation in mice with disruption of the plasminogen gene

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Loss of fibrinogen rescues mice from the pleiotropic effects of plasminogen deficiency.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Borrelia burgdorferi induces secretion of pro-urokinase-type plasminogen activator by human monocytes.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

A new Borrelia species isolated from patients with relapsing fever in Spain

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Inhibition of Borrelia burgdorferi-bound fibrinolytic enzymes by alpha2-antiplasmin, PAI-1 and PAI-2.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Experimental infection of the mouse brain by a relapsing fever Borrelia species: a molecular analysis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Integrin alpha IIb beta 3 mediates binding of the Lyme disease agent Borrelia burgdorferi to human platelets

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Extracellular proteolysis in the adult murine brain

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Heritable susceptibility to severe Borrelia burgdorferi-induced arthritis is dominant and is associated with persistence of large numbers of spirochetes in tissues

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Variability of a bacterial surface protein and disease expression in a possible mouse model of systemic Lyme borreliosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Antigen diversity in the bacterium B. hermsii through "somatic" mutations in rearranged vmp genes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

An endothelial cell receptor for plasminogen/tissue plasminogen activator. I. Identity with annexin II.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

The outer surface protein A of the spirochete Borrelia burgdorferi is a plasmin(ogen) receptor

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Borrelia burgdorferi binds plasminogen, resulting in enhanced penetration of endothelial monolayers

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Binding of human plasminogen to Borrelia burgdorferi

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Expression of the macrophage-specific antigen F4/80 during differentiation of mouse bone marrow cells in culture

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Experimental Relapsing Fever Initiated by Borrelia hermsi: II. Sequential Appearance of Major Serotypes in the Rat

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Immunohistochemical localization of macrophages and microglia in the adult and developing mouse brain

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Plasminogen activators, tissue degradation, and cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Antigenic variation is associated with DNA rearrangements in a relapsing fever Borrelia.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Human monocytes can produce tissue-type plasminogen activator

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Antigenic variation of a relapsing fever Borrelia species

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Lyme borreliosis in the severe combined immunodeficiency (scid) mouse manifests predominantly in the joints, heart, and liver

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Kinetics of Borrelia burgdorferi dissemination and evolution of disease after intradermal inoculation of mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

The plasminogen activator/plasmin system

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

A surface protease and the invasive character of plague

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Tissue-type plasminogen activator-mediated activation of plasminogen on the surface of group A, C, and G streptococci

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Borrelia burgdorferi adherence and injury to undifferentiated and differentiated neural cells in vitro.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Adherence of the Lyme disease spirochete to glial cells and cells of glial origin.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Neuronal death in the hippocampus is promoted by plasmin-catalyzed degradation of laminin.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Vascular clearance of Borrelia burgdorferi in rats.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Concomitant secretion of prourokinase and of a plasminogen activator-specific inhibitor by cultured human monocytes-macrophages

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Borrelia burgdorferi in the central nervous system: experimental and clinical evidence for early invasion

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=407868

Plasminogen deficiency causes severe thrombosis but is compatible with development and reproduction

31 October 2018

1 reference

12 December 2020

Binding of human plasminogen and urokinase-type plasminogen activator to the Lyme disease spirochete, Borrelia burgdorferi

1 reference

12 December 2020

Impaired wound healing in mice with a disrupted plasminogen gene

1 reference

12 December 2020

Plasminogen activation by invasive human pathogens

1 reference

12 December 2020

An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus

1 reference

12 December 2020

Healing of corneal epithelial defects in plasminogen- and fibrinogen-deficient mice

1 reference

12 December 2020

Borrelia burgdorferi and other related spirochetes bind to galactocerebroside

1 reference

12 December 2020

Streptokinase-producing streptococci grown in human plasma acquire unregulated cell-associated plasmin activity

1 reference

12 December 2020

Mechanism of activation of human plasminogen by streptokinase. Presence of active center in streptokinase-plasminogen complex

1 reference

12 December 2020

Lyme neuroborreliosis

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI5171

1 reference

27 July 2017

1 reference

27 July 2017

1 reference