(Q33506224)

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Employing a recombinant HLA-DR3 expression system to dissect major histocompatibility complex II-thyroglobulin peptide dynamism: a genetic, biochemical, and reverse immunological perspective

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Employing a recombinant HLA-DR3 expression system to dissect major histocompatibility complex II-thyroglobulin peptide dynamism: a genetic, biochemical, and reverse immunological perspective (English)

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

1 reference

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author name string

Eric M Jacobson

1

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Heyi Yang

2

1 reference

Europe PubMed Central

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27 July 2017

Francesca Menconi

3

1 reference

Europe PubMed Central

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27 July 2017

Rong Wang

4

1 reference

Europe PubMed Central

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27 July 2017

Roman Osman

5

1 reference

Europe PubMed Central

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27 July 2017

Luce Skrabanek

6

1 reference

Europe PubMed Central

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27 July 2017

Cheuk Wun Li

7

1 reference

Europe PubMed Central

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27 July 2017

Mohammed Fadlalla

8

1 reference

Europe PubMed Central

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27 July 2017

Alisha Gandhi

9

1 reference

Europe PubMed Central

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27 July 2017

Vijaya Chaturvedi

10

1 reference

Europe PubMed Central

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27 July 2017

Eric P Smith

11

1 reference

Europe PubMed Central

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27 July 2017

Sandy Schwemberger

12

1 reference

Europe PubMed Central

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27 July 2017

Andrew Osterburg

13

1 reference

Europe PubMed Central

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27 July 2017

George F Babcock

14

1 reference

Europe PubMed Central

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27 July 2017

Yaron Tomer

15

1 reference

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27 July 2017

language of work or name

0 references

publication date

23 September 2009

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Europe PubMed Central

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27 July 2017

Journal of Biological Chemistry

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Europe PubMed Central

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27 July 2017

284

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Europe PubMed Central

PubMed publication ID

27 July 2017

49

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

34231-34243

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Molecular amino acid signatures in the MHC class II peptide-binding pocket predispose to autoimmune thyroiditis in humans and in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

The HLA gene complex in thyroid autoimmunity: from epidemiology to etiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

The genetic basis of thyroid autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Post-translational modifications of naturally processed MHC-binding epitopes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Endosomal proteases in antigen presentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Cathepsin L is essential for onset of autoimmune diabetes in NOD mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Amino acid substitutions in the thyroglobulin gene are associated with susceptibility to human and murine autoimmune thyroid disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Thyroid functions of mouse cathepsins B, K, and L.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Point Mutations in or Near the Antigen-Binding Groove of HLA-DR3 Implicate Class II-Associated Invariant Chain Peptide Affinity as a Constraint on MHC Class II Polymorphism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

HLA class II peptide-binding and autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Expression and crystallization of the complex of HLA-DR2 (DRA, DRB1*1501) and an immunodominant peptide of human myelin basic protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Crystallographic analysis of endogenous peptides associated with HLA-DR1 suggests a common, polyproline II-like conformation for bound peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Structural basis for major histocompatibility complex (MHC)-linked susceptibility to autoimmunity: charged residues of a single MHC binding pocket confer selective presentation of self-peptides in pemphigus vulgaris

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

JunB differs from c-Jun in its DNA-binding and dimerization domains, and represses c-Jun by formation of inactive heterodimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Refolding of human class II major histocompatibility complex molecules isolated from Escherichia coli. Assembly of peptide-free heterodimers and increased refolding-yield in the presence of antigenic peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Acquisition of peptides by MHC class II polypeptides in the absence of the invariant chain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Microvariation creates significant functional differences in the DR3 molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Gamma-interferon causes a selective induction of the lysosomal proteases, cathepsins B and L, in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Peptide binding specificity of HLA-DR4 molecules: correlation with rheumatoid arthritis association

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Thyroid Antigens and Autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Purification and characterization of class II histocompatibility antigens from a homozygous human B cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Thyroglobulin processing by thyroidal proteases. Major sites of cleavage by cathepsins B, D, and L

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Role of cathepsin D in antigen presentation of ovalbumin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-Ad

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

21 June 2018

Arginine at position 74 of the HLA-DR beta1 chain is associated with Graves' disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.041574

21 January 2018

Thyroglobulin peptides associate in vivo to HLA-DR in autoimmune thyroid glands

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.041574

21 January 2018

Empty and peptide-loaded class II major histocompatibility complex proteins produced by expression in Escherichia coli and folding in vitro.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.041574

21 January 2018

Converging free energy estimates: MM-PB(GB)SA studies on the protein-protein complex Ras-Raf.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.041574

21 January 2018

Association of the thyroid stimulating hormone receptor gene (TSHR) with Graves' disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.041574

21 January 2018

Acetylcholine receptor peptide recognition in HLA DR3-transgenic mice: in vivo responses correlate with MHC-peptide binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.041574

21 January 2018

Pathogenic human thyroglobulin peptides in HLA-DR3 transgenic mouse model of autoimmune thyroiditis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.041574

21 January 2018

Thyroid functions of mouse cathepsins B, K, and L

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.041574

21 January 2018

CTLA-4 and not CD28 is a susceptibility gene for thyroid autoantibody production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797193

31 October 2018

Insights into autoimmunity gained from structural analysis of MHC-peptide complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19776016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MHC-linked susceptibility to type 1 diabetes: a structural perspective

1 reference

https://pubmed.ncbi.nlm.nih.gov/19776016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Separation of three class II antigens from a homozygous human B cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/19776016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant expression of HLA-DR antigen on thyrocytes in Graves' disease: relevance for autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19776016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of aberrant HLA-DR expression and antigen presentation in induction of endocrine autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19776016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of Thyroidal Thiol Endopeptidases by Thyrotropin*

1 reference

https://pubmed.ncbi.nlm.nih.gov/19776016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Molecular Basis for MHC Class II—Associated Autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19776016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The specificity of alloreactive T cells is determined by MHC polymorphisms which contact the T cell receptor and which influence peptide binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/19776016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HLA-DRα chain residues located on the outer loops are involved in nonpolymorphic and polymorphic antibody-binding epitopes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19776016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cathepsin B activity and protein levels in thyroid carcinoma, Graves' disease, and multinodular goiters

1 reference

https://pubmed.ncbi.nlm.nih.gov/19776016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human thyroglobulin peptide p2340 induces autoimmune thyroiditis in HLA-DR3 transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19776016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible interaction between HLA-DRbeta1 and thyroglobulin variants in Graves' disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19776016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M109.041574

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

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