(Q40653189)

English

Point Mutations in or Near the Antigen-Binding Groove of HLA-DR3 Implicate Class II-Associated Invariant Chain Peptide Affinity as a Constraint on MHC Class II Polymorphism

scientific article published on May 1, 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Point mutations in or near the antigen-binding groove of HLA-DR3 implicate class II-associated invariant chain peptide affinity as a constraint on MHC class II polymorphism (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Point Mutations in or Near the Antigen-Binding Groove of HLA-DR3 Implicate Class II-Associated Invariant Chain Peptide Affinity as a Constraint on MHC Class II Polymorphism (English)

1 reference

10.4049/JIMMUNOL.170.9.4683

https://api.crossref.org/works/10.4049/JIMMUNOL.170.9.4683

26 December 2023

1 reference

10.4049/JIMMUNOL.170.9.4683

https://api.crossref.org/works/10.4049/JIMMUNOL.170.9.4683

26 December 2023

6

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Robert Busch

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707347

26 December 2023

Elizabeth D Mellins

7

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Elizabeth D. Mellins

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707347

26 December 2023

author name string

Achal Pashine

2

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Europe PubMed Central

PubMed publication ID

22 September 2017

Wendy Liu

3

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Europe PubMed Central

PubMed publication ID

22 September 2017

Michael Belmares

5

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Europe PubMed Central

PubMed publication ID

22 September 2017

Robert C. Doebele

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707347

26 December 2023

Dennis M. Zaller

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707347

26 December 2023

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publication date

1 May 2003

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Europe PubMed Central

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22 September 2017

full work available at URL

Journal of Immunology

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Europe PubMed Central

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22 September 2017

170

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Europe PubMed Central

PubMed publication ID

22 September 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

4683-4692

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules

1 reference

4 November 2023

https://opencitations.net/index/coci/api/v1/citations/10.1038/368551A0

Binding interactions between peptides and proteins of the class II major histocompatibility complex

1

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

MHC ligands and peptide motifs: first listing

2

1 reference

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26 December 2023

Assembly, transport, and function of MHC class II molecules

3

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3

4

1 reference

10.4049/JIMMUNOL.170.9.4683

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A study of complexes of class II invariant chain peptide: major histocompatibility complex class II molecules using a new complex-specific monoclonal antibody.

5

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One of two unstructured domains of Ii becomes ordered in complexes with MHC class II molecules

6

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26 December 2023

The role of lysosomal proteinases in MHC class II-mediated antigen processing and presentation

7

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26 December 2023

Proteolysis in MHC class II antigen presentation: who's in charge?

8

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10.4049/JIMMUNOL.170.9.4683

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26 December 2023

Formation of a highly peptide-receptive state of class II MHC.

9

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II.

10

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

Sequence analysis of peptides bound to MHC class II molecules

11

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26 December 2023

Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

12

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-Ad

13

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

Accessory molecules for MHC class II peptide loading

14

1 reference

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A mutant human histocompatibility leukocyte antigen DR molecule associated with invariant chain peptides

15

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10.4049/JIMMUNOL.170.9.4683

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Antigen presentation and T cell development in H2-M-deficient mice

17

1 reference

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26 December 2023

H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection

18

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway

19

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

Relaxed DM requirements during class II peptide loading and CD4+ T cell maturation in BALB/c mice

20

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

Molecular modeling and design of invariant chain peptides with altered dissociation kinetics from class II MHC.

22

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

Human histocompatibility leukocyte antigen (HLA)-DM edits peptides presented by HLA-DR according to their ligand binding motifs

23

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM

24

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10.4049/JIMMUNOL.170.9.4683

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Episomal vectors rapidly and stably produce high-titer recombinant retrovirus

25

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10.4049/JIMMUNOL.170.9.4683

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26 December 2023

Determination of the HLA-DM interaction site on HLA-DR molecules

26

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

In vivo and in vitro formation and dissociation of HLA-DR complexes with invariant chain-derived peptides

27

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

Monoclonal anti-Ia murine alloantibodies crossreactive with the Ia-homologues of other mammalian species including humans

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1 reference

10.4049/JIMMUNOL.170.9.4683

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Differential expression and serologically distinct subpopulations of human Ia antigens detected with monoclonal antibodies to Ia alpha and beta chains

31

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

The human class II MHC protein HLA-DR1 assembles as empty alpha beta heterodimers in the absence of antigenic peptide

33

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

Mediation by HLA-DM of dissociation of peptides from HLA-DR

34

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

Secondary structure composition and pH-dependent conformational changes of soluble recombinant HLA-DM.

35

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

Immunochemically purified DR antigens in liposomes stimulate xenogeneic cytolytic T cells in secondary in vitro cultures

36

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments

38

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

Point mutations define positions in HLA-DR3 molecules that affect antigen presentation

39

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells

40

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10.4049/JIMMUNOL.170.9.4683

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Defective processing and presentation of exogenous antigens in mutants with normal HLA class II genes

42

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

The generation of SDS-stable HLA DR dimers is independent of efficient peptide binding

43

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10.4049/JIMMUNOL.170.9.4683

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26 December 2023

Beta 57-Asp plays an essential role in the unique SDS stability of HLA-DQA1*0102/DQB1*0602 alpha beta protein dimer, the class II MHC allele associated with protection from insulin-dependent diabetes mellitus

45

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

Identification of the lateral interaction surfaces of human histocompatibility leukocyte antigen (HLA)-DM with HLA-DR1 by formation of tethered complexes that present enhanced HLA-DM catalysis

46

1 reference

10.4049/JIMMUNOL.170.9.4683

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Structural factors contributing to DM susceptibility of MHC class II/peptide complexes

47

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

HLA-DM acts as a molecular chaperone and rescues empty HLA-DR molecules at lysosomal pH

48

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules

49

1 reference

10.4049/JIMMUNOL.170.9.4683

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26 December 2023

The kinetic basis of peptide exchange catalysis by HLA-DM

51

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10.4049/JIMMUNOL.170.9.4683

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Specific treatment of autoimmunity with recombinant invariant chains in which CLIP is replaced by self-epitopes

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The specificity of alloreactive T cells is determined by MHC polymorphisms which contact the T cell receptor and which influence peptide binding

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IMGT/HLA Database--a sequence database for the human major histocompatibility complex

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10.4049/JIMMUNOL.170.9.4683

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The gene conversion hypothesis of MHC evolution: a review

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Rheumatoid arthritis (RA)-associated HLA-DR alleles form less stable complexes with class II-associated invariant chain peptide than non-RA-associated HLA-DR alleles

57

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HLA class II regulation and structure. Analysis with HLA-DR3 and HLA-DP point mutants

58

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A gene required for class II-restricted antigen presentation maps to the major histocompatibility complex

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Deletion mapping of HLA and chromosome 6p genes

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26 December 2023

Identifiers

10.4049/JIMMUNOL.170.9.4683

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

ResearchGate publication ID

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