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HLA-DM acts as a molecular chaperone and rescues empty HLA-DR molecules at lysosomal pH
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
9075930
retrieved
3 February 2017
title
HLA-DM acts as a molecular chaperone and rescues empty HLA-DR molecules at lysosomal pH
(English)
1 reference
stated in
PubMed
PubMed ID
9075930
retrieved
3 February 2017
main subject
molecular chaperones
0 references
author name string
H. Kropshofer
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
9075930
retrieved
3 February 2017
S. O. Arndt
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
9075930
retrieved
3 February 2017
G. Moldenhauer
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
9075930
retrieved
3 February 2017
G. J. Hämmerling
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
9075930
retrieved
3 February 2017
A. B. Vogt
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
9075930
retrieved
3 February 2017
language of work or name
English
0 references
publication date
1 March 1997
1 reference
stated in
PubMed
PubMed ID
9075930
retrieved
3 February 2017
published in
Immunity
1 reference
stated in
PubMed
PubMed ID
9075930
retrieved
3 February 2017
volume
6
1 reference
stated in
PubMed
PubMed ID
9075930
retrieved
3 February 2017
page(s)
293–302
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stated in
PubMed
PubMed ID
9075930
retrieved
3 February 2017
issue
3
1 reference
stated in
PubMed
PubMed ID
9075930
retrieved
3 February 2017
cites work
In vivo and in vitro formation and dissociation of HLA-DR complexes with invariant chain-derived peptides
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MHC class II-associated invariant chain contains a sorting signal for endosomal compartments
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mapping functional regions in the lumenal domain of the class II-associated invariant chain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extensive trafficking of MHC class II-invariant chain complexes in the endocytic pathway and appearance of peptide-loaded class II in multiple compartments
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
New class II-like genes in the murine MHC.
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
HLA-DM induces CLIP dissociation from MHC class II alpha beta dimers and facilitates peptide loading
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular Chaperones
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes surface expression of occupied molecules
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetics of intracellular transport and sorting of lysosomal membrane and plasma membrane proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Reconstitution of an operational MHC class II compartment in nonantigen-presenting cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
A new human HLA class II-related locus, DM
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Self and foreign peptides interact with intact and disassembled MHC class II antigen HLA-DR via tryptophan pockets
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural features of the invariant chain fragment CLIP controlling rapid release from HLA-DR molecules and inhibition of peptide binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Self-release of CLIP in peptide loading of HLA-DR molecules
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How HLA-DM edits the MHC class II peptide repertoire: survival of the fittest?
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Invariant chain targets HLA class II molecules to acidic endosomes containing internalized influenza virus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The MHC class II molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motif
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Purification and characterization of human lysosomal membrane glycoproteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endosomal aspartic proteinases are required for invariant-chain processing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transient aggregation of major histocompatibility complex class II chains during assembly in normal spleen cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A lysosomal targeting signal in the cytoplasmic tail of the beta chain directs HLA-DM to MHC class II compartments.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of peptides bound to extracellular and intracellular HLA-DR1 molecules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HLA-DM is localized to conventional and unconventional MHC class II-containing endocytic compartments.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Formation of a nine-subunit complex by HLA class II glycoproteins and the invariant chain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for peptide in determining MHC class II structure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MHC class II function preserved by low-affinity peptide interactions preceding stable binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association between HLA-DM and HLA-DR in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HLA-DR associates with specific stress proteins and is retained in the endoplasmic reticulum in invariant chain negative cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mediation by HLA-DM of dissociation of peptides from HLA-DR.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HLA-A- and HLA-B-specific monoclonal antibodies reactive with free heavy chains in western blots, in formalin-fixed, paraffin-embedded tissue sections and in cryo-immuno-electron microscopy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human class II MHC protein HLA-DR1 assembles as empty alpha beta heterodimers in the absence of antigenic peptide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation and characterization of the intracellular MHC class II compartment.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective release of some invariant chain-derived peptides from HLA-DR1 molecules at endosomal pH
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human histocompatibility leukocyte antigen (HLA)-DM edits peptides presented by HLA-DR according to their ligand binding motifs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The generation of SDS-stable HLA DR dimers is independent of efficient peptide binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice lacking the MHC class II-associated invariant chain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetic analysis of peptide loading onto HLA-DR molecules mediated by HLA-DM.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1074-7613(00)80332-5
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3987389
OpenCitations bibliographic resource ID
3987389
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3987389
PubMed ID
9075930
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3987389
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