(Q33509503)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

From disease association to risk assessment: an optimistic view from genome-wide association studies on type 1 diabetes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

genome-wide association study

9 February 2020

main subject

0 references

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Joseph Glessner

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Charles A Stanley

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Struan F.A. Grant

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Constantin Polychronakos

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

12

Dimitri Monos

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

15

Hakon Hakonarson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

2

Kai Wang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

5

Jonathan Bradfield

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

10

Rosetta Chiavacci

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

8

Cuiping Hou

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

7

Edward Frackleton

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

Zhi Wei

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Haitao Zhang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Cecilia Kim

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

publication date

9 October 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

page(s)

e1000678

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

9 February 2020

copyright license

start time

9 October 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Predicting human height by Victorian and genomic methods

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Interpretation of genetic association studies: markers with replicated highly significant odds ratios may be poor classifiers

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Cardiovascular disease risk prediction with and without knowledge of genetic variation at chromosome 9p21.3.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Common variants at 30 loci contribute to polygenic dyslipidemia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Predicting unobserved phenotypes for complex traits from whole-genome SNP data

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Accuracy of predicting the genetic risk of disease using a genome-wide approach

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Genome-based prediction of common diseases: advances and prospects

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Prediction of individual genetic risk of complex disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

The molecular genetics of type 1 diabetes: new genes and emerging mechanisms

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Genome-wide association analysis identifies 20 loci that influence adult height

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Many sequence variants affecting diversity of adult human height

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Identification of ten loci associated with height highlights new biological pathways in human growth

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

The NCBI dbGaP database of genotypes and phenotypes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Prediction of individual genetic risk to disease from genome-wide association studies

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

New models of collaboration in genome-wide association studies: the Genetic Association Information Network

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

PLINK: a tool set for whole-genome association and population-based linkage analyses

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

A method to address differential bias in genotyping in large-scale association studies

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

What is a support vector machine?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Combining information from common type 2 diabetes risk polymorphisms improves disease prediction

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Principal components analysis corrects for stratification in genome-wide association studies

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Genetics of Kidneys in Diabetes (GoKinD) study: a genetics collection available for identifying genetic susceptibility factors for diabetic nephropathy in type 1 diabetes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Quantifying the health benefits of genetic tests: the importance of a population perspective

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Type 2 diabetes: principles of pathogenesis and therapy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Genetic liability of type 1 diabetes and the onset age among 22,650 young Finnish twin pairs: a nationwide follow-up study

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Population stratification and spurious allelic association

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Knowledge-based analysis of microarray gene expression data by using support vector machines

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Assessing the role of HLA-linked and unlinked determinants of disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2748686

Impact of common type 2 diabetes risk polymorphisms in the DESIR prospective study

14 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000678

Value of genetic profiling for the prediction of coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000678

Penalized logistic regression for detecting gene interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000678

Ridge Estimators in Logistic Regression

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000678

Genetic risk prediction--are we there yet?

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19816555

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1000678

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19816555%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

19816555

1 reference