(Q33518799)

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Fluorescent high-content imaging allows the discrimination and quantitation of E-LDL-induced lipid droplets and Ox-LDL-generated phospholipidosis in human macrophages

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scholarly article

1 reference

Europe PubMed Central

27 July 2017

Fluorescent high-content imaging allows the discrimination and quantitation of E-LDL-induced lipid droplets and Ox-LDL-generated phospholipidosis in human macrophages (English)

1 reference

Europe PubMed Central

27 July 2017

object named as

Gerd Schmitz

2

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author name string

Margot Grandl

1

1 reference

Europe PubMed Central

27 July 2017

publication date

1 March 2010

1 reference

Europe PubMed Central

27 July 2017

Cytometry Part A

1 reference

Europe PubMed Central

27 July 2017

77

1 reference

Europe PubMed Central

27 July 2017

231-242

1 reference

Europe PubMed Central

27 July 2017

3

1 reference

Europe PubMed Central

27 July 2017

Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice: pleiotropic effects on CD36 expression and HDL.

1 reference

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Fixation Methods for the Study of Lipid Droplets by Immunofluorescence Microscopy

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Endolysosomal phospholipidosis and cytosolic lipid droplet storage and release in macrophages

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21 January 2018

Aggregated LDL and lipid dispersions induce lysosomal cholesteryl ester accumulation in macrophage foam cells

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Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis

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Lipid in the aortic intima the correlation of morphological and chemical characteristics

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Caveolin, cholesterol, and lipid bodies

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Lipid droplets: a unified view of a dynamic organelle

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A caveolin dominant negative mutant associates with lipid bodies and induces intracellular cholesterol imbalance

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Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains

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Regulation of adipocyte gene expression and differentiation by peroxisome proliferator activated receptor gamma

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PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL

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Flow cytometric analysis of lipid droplet formation in cells of the human monocytic cell line, U937.

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Granulocyte colony-stimulating factor-induced terminal maturation of human myeloid cells is specifically associated with up-regulation of receptor-mediated function and CD10 expression

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7 January 2021

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Factors underlying the variability of lipid droplet fluorescence in MA-10 Leydig tumor cells

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Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes

1 reference

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7 January 2021

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Imaging of lipid biosynthesis: how a neutral lipid enters lipid droplets

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Functional interactions between Mldp (LSDP5) and Abhd5 in the control of intracellular lipid accumulation

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Nile red: a selective fluorescent stain for intracellular lipid droplets

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Live cell multicolor imaging of lipid droplets with a new dye, LD540.

1 reference

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Enzymatically degraded LDL preferentially binds to CD14(high) CD16(+) monocytes and induces foam cell formation mediated only in part by the class B scavenger-receptor CD36

1 reference

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7 January 2021

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Scavenger receptors and oxidized low density lipoproteins

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7 January 2021

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Uptake and trafficking of mildly oxidized LDL and acetylated LDL in THP-1 cells does not explain the differences in lysosomal metabolism of these two lipoproteins.

1 reference

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Drug-induced phospholipidosis

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Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis

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7 January 2021

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Validation of an in vitro screen for phospholipidosis using a high-content biology platform

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Phospholipidosis assay in HepG2 cells and rat or rhesus hepatocytes using phospholipid probe NBD-PE.

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7 January 2021

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Characterization of the phospholipidogenic potential of 4(1H)-pyridone antimalarial derivatives

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Cell-based fluorescence assay for evaluation of new-drugs potential for phospholipidosis in an early stage of drug development

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7 January 2021

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In vitro detection of drug-induced phospholipidosis using gene expression and fluorescent phospholipid based methodologies

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7 January 2021

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Establishment of an in vitro high-throughput screening assay for detecting phospholipidosis-inducing potential

1 reference

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7 January 2021

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Flow cytometry, with double staining with Nile red and anti-CD3 antibody, to detect phospholipidosis in peripheral blood lymphocytes of rats treated with amiodarone

1 reference

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7 January 2021

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A clinical flow cytometric biomarker strategy: validation of peripheral leukocyte phospholipidosis using Nile red.

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Effects of caspase inhibitors (z-VAD-fmk, z-VDVAD-fmk) on Nile Red fluorescence pattern in 7-ketocholesterol-treated cells: investigation by flow cytometry and spectral imaging microscopy

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A cell-based approach for the early assessment of the phospholipidogenic potential in pharmaceutical research and drug development.

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Nile red staining of lysosomal phospholipid inclusions

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Enhanced upregulation of the Fc gamma receptor IIIa (CD16a) during in vitro differentiation of ApoE4/4 monocytes

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Low density lipoprotein undergoes oxidative modification in vivo

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Analysis of two matrix metalloproteinase inhibitors and their metabolites for induction of phospholipidosis in rat and human hepatocytes(1).

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10.1002/CYTO.A.20828

1 reference

Europe PubMed Central

27 July 2017

1 reference

Europe PubMed Central

27 July 2017

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