(Q33519555)

27 July 2017

title

Route of administration of the TLR9 agonist CpG critically determines the efficacy of cancer immunotherapy in mice (English)

1 reference

27 July 2017

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1 reference

Stefan Nierkens

1

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Carl Figdor

object named as

Carl G Figdor

5

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Gosse J Adema

7

object named as

Gosse J Adema

1 reference

27 July 2017

Martijn H den Brok

2

1 reference

27 July 2017

Thijs Roelofsen

3

1 reference

27 July 2017

Jori A L Wagenaars

4

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27 July 2017

Theo J Ruers

6

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27 July 2017

language of work or name

English

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publication date

18 December 2009

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27 July 2017

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27 July 2017

volume

4

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27 July 2017

issue

12

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27 July 2017

page(s)

e8368

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Creative Commons Attribution 4.0 International

27 July 2017

copyright license

start time

18 December 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

In vivo colocalization of antigen and CpG [corrected] within dendritic cells is associated with the efficacy of cancer immunotherapy

1 reference

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Toll-like receptor signalling on Tregs: to suppress or not to suppress?

21 June 2018

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Radiofrequency ablation versus resection for resectable colorectal liver metastases: time for a randomized trial?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

CPG-7909 (PF-3512676, ProMune): toll-like receptor-9 agonist in cancer therapy.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

Human monocyte-derived dendritic cells express TLR9 and react directly to the CpG-A oligonucleotide D19.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

Efficient loading of dendritic cells following cryo and radiofrequency ablation in combination with immune modulation induces anti-tumour immunity.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

The mannose receptor mediates uptake of soluble but not of cell-associated antigen for cross-presentation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

Toll-like receptor 9-mediated induction of the immunosuppressive pathway of tryptophan catabolism.

21 June 2018

1 reference

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Cutting edge: CpG oligonucleotides induce splenic CD19+ dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN Type 1 signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

Dendritic cells: tools and targets for antitumor vaccination

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

Cross-presentation: underlying mechanisms and role in immune surveillance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

CpG oligonucleotide therapy cures subcutaneous and orthotopic tumors and evokes protective immunity in murine bladder cancer.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner.

21 June 2018

1 reference

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In situ tumor ablation creates an antigen source for the generation of antitumor immunity

21 June 2018

1 reference

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Induction of potent antitumor immunity by in situ targeting of intratumoral DCs.

21 June 2018

1 reference

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Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

Dendritic cells charged with apoptotic tumor cells induce long-lived protective CD4+ and CD8+ T cell immunity against B16 melanoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

CpG motifs in bacterial DNA and their immune effects

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

Interleukin 15-dependent crosstalk between conventional and plasmacytoid dendritic cells is essential for CpG-induced immune activation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

Systemic application of CpG-rich DNA suppresses adaptive T cell immunity via induction of IDO.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

Accelerated CD8+ T-cell memory and prime-boost response after dendritic-cell vaccination.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

The reciprocal interaction of NK cells with plasmacytoid or myeloid dendritic cells profoundly affects innate resistance functions.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

CpG oligodeoxynucleotide enhances tumor response to radiation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

Generation of antitumor immunity by cytotoxic T lymphocyte epitope peptide vaccination, CpG-oligodeoxynucleotide adjuvant, and CTLA-4 blockade.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

Spontaneous regression of pulmonary metastases from renal cell carcinoma after radio frequency ablation of primary tumor: an in situ tumor vaccine?

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

Peritumoral CpG DNA elicits a coordinated response of CD8 T cells and innate effectors to cure established tumors in a murine colon carcinoma model.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

Migratory Dendritic Cells Transfer Antigen to a Lymph Node-Resident Dendritic Cell Population for Efficient CTL Priming

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791230

CPG 7909, an immunostimulatory TLR9 agonist oligodeoxynucleotide, as adjuvant to Engerix-B HBV vaccine in healthy adults: a double-blind phase I/II study

31 October 2018

1 reference

12 December 2020

Improving the therapeutic index of CpG oligodeoxynucleotides by intralymphatic administration

1 reference

12 December 2020

Phase I study of percutaneous cryotherapy for colorectal liver metastasis

1 reference

12 December 2020

Immune-mediated tumor regression induced by CpG-containing oligodeoxynucleotides

1 reference

12 December 2020

Targeting antigen into the phagocytic pathway in vivo induces protective tumour immunity

1 reference

12 December 2020

Induction of systemic TH1-like innate immunity in normal volunteers following subcutaneous but not intravenous administration of CPG 7909, a synthetic B-class CpG oligodeoxynucleotide TLR9 agonist

1 reference

12 December 2020

Synergy between In situ Cryoablation and TLR9 Stimulation Results in a Highly Effective In vivo Dendritic Cell Vaccine

1 reference

12 December 2020

Clinical setbacks for toll-like receptor 9 agonists in cancer

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0008368

Identifiers

DOI

1 reference

27 July 2017

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1 reference

27 July 2017

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