(Q33526360)

27 July 2017

Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease (English)

1 reference

27 July 2017

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21

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27 July 2017

25

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27 July 2017

41

1 reference

27 July 2017

23

Igor Rudan

0 references

Veronique Vitart

20

Veronique Vitart

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Christopher M Watson

Christopher M Watson

18

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Stephen Todd

Stephen Todd

30

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Kevin Morgan

Kevin Morgan

46

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Patrick G. Kehoe

Patrick G Kehoe

31

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Clive Holmes

Clive Holmes

36

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Nilüfer Ertekin-Taner

6

Nilufer Ertekin-Taner

1 reference

27 July 2017

43

Ronald C Petersen

1 reference

27 July 2017

Bernadette McGuinness

29

Bernadette McGuinness

1 reference

27 July 2017

24

Harry Campbell

1 reference

27 July 2017

22

Nicholas D Hastie

1 reference

27 July 2017

7

Morad Ansari

1 reference

27 July 2017

17

Chloe M Stanton

1 reference

27 July 2017

39

Noor Kalsheker

1 reference

27 July 2017

Minerva M Carrasquillo

1

Minerva M Carrasquillo

1 reference

27 July 2017

Neill R Graff-Radford

42

Neill R Graff-Radford

1 reference

27 July 2017

5

Mariet Allen

1 reference

27 July 2017

4

Fanggeng Zou

1 reference

27 July 2017

13

Curtis S Younkin

1 reference

27 July 2017

40

V Shane Pankratz

1 reference

27 July 2017

26

Kristelle Brown

1 reference

27 July 2017

8

Samantha L Wilcox

1 reference

27 July 2017

12

Samuel G Younkin

1 reference

27 July 2017

11

Linda H Younkin

1 reference

27 July 2017

16

Chanley C Howell

1 reference

27 July 2017

44

Alan F Wright

1 reference

27 July 2017

45

Steven G Younkin

1 reference

27 July 2017

Olivia Belbin

2

1 reference

27 July 2017

Olivia Belbin

3

1 reference

27 July 2017

Mariah R Kashino

9

1 reference

27 July 2017

Li Ma

10

1 reference

27 July 2017

Toros A Dincman

14

1 reference

27 July 2017

Melissa E Howard

15

1 reference

27 July 2017

Michael Crump

19

1 reference

27 July 2017

Peter Passmore

27

1 reference

27 July 2017

David Craig

28

1 reference

27 July 2017

David M Mann

32

1 reference

27 July 2017

A David Smith

33

1 reference

27 July 2017

Helen Beaumont

34

1 reference

27 July 2017

Donald Warden

35

1 reference

27 July 2017

Reinhard Heun

37

1 reference

27 July 2017

Heike Kölsch

38

1 reference

27 July 2017

language of work or name

English

0 references

publication date

19 January 2010

1 reference

27 July 2017

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27 July 2017

5

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27 July 2017

1

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27 July 2017

e8764

1 reference

Creative Commons Attribution 4.0 International

27 July 2017

start time

19 January 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Genome-wide association study of biochemical traits in Korcula Island, Croatia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

PLINK: a tool set for whole-genome association and population-based linkage analyses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

GenABEL: an R library for genome-wide association analysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: review and hypothesis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Mutation screening of a haplotype block around the insulin degrading enzyme gene and association with Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Deciphering the molecular basis of memory failure in Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

The current status of Alzheimer's disease genetics: what do we tell the patients?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Haploview: analysis and visualization of LD and haplotype maps

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Sequence variation in the proximity of IDE may impact age at onset of both Parkinson disease and Alzheimer disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Genetic variants in a haplotype block spanning IDE are significantly associated with plasma Abeta42 levels and risk for Alzheimer disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Genetic variation in a haplotype block spanningIDE influences Alzheimer disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Results of a high-resolution genome screen of 437 Alzheimer's disease families

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Score tests for association between traits and haplotypes when linkage phase is ambiguous

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Heritability for Alzheimer's disease: the study of dementia in Swedish twins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Lack of association of 5 SNPs in the vicinity of the insulin-degrading enzyme (IDE) gene with late-onset Alzheimer's disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Positive association between risk for late-onset Alzheimer disease and genetic variation in IDE.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Weak independent association signals between IDE polymorphisms, Alzheimer's disease and cognitive measures.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Insulin degrading enzyme and alpha-3 catenin polymorphisms in Italian patients with Alzheimer disease.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Alternative splicing of human insulin-degrading enzyme yields a novel isoform with a decreased ability to degrade insulin and amyloid beta-protein

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Sequence variants of IDE are associated with the extent of beta-amyloid deposition in the Alzheimer's disease brain.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Insulin-degrading enzyme and Alzheimer disease: a genetic association study in the Han Chinese.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Insulin-degrading enzyme, apolipoprotein E, and Alzheimer's disease.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

No association between the insulin degrading enzyme gene and Alzheimer's disease in a Japanese population.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Insulin degrading enzyme (IDE) genetic variants and risk of Alzheimer's disease: evidence of effect modification by apolipoprotein E (APOE).

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Polymorphisms of insulin degrading enzyme gene are not associated with Alzheimer's disease.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Confirmation of association between D10S583 and Alzheimer's disease in a case--control sample.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Case-control studies of genetic markers: power and sample size approximations for Armitage's test for trend

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

A full genome scan for late onset Alzheimer's disease.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

Effects of genome-wide heterozygosity on a range of biomedically relevant human quantitative traits

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808243

The role of heredity in late-onset Alzheimer disease and vascular dementia. A twin study

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20098734

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Evidence for genetic linkage of Alzheimer's disease to chromosome 10q

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20098734

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0008764

1 reference

27 July 2017

0 references

1 reference

27 July 2017

1 reference