(Q33534390)

27 July 2017

Total synthesis and biological evaluation of largazole and derivatives with promising selectivity for cancers cells (English)

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27 July 2017

Marc C Nicklaus

8

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author name string

Xin Zeng

1

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27 July 2017

Biaolin Yin

2

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27 July 2017

Zheng Hu

3

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27 July 2017

Chenzhong Liao

4

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27 July 2017

Jinglei Liu

5

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27 July 2017

Shang Li

6

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27 July 2017

Zheng Li

7

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27 July 2017

Guangbiao Zhou

9

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27 July 2017

Sheng Jiang

10

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27 July 2017

language of work or name

English

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publication date

1 March 2010

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27 July 2017

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27 July 2017

12

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27 July 2017

6

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27 July 2017

1368-1371

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Structure and activity of largazole, a potent antiproliferative agent from the Floridian marine cyanobacterium Symploca sp.

27 July 2017

1 reference

12 December 2020

Total synthesis and biological mode of action of largazole: a potent class I histone deacetylase inhibitor

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12 December 2020

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

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12 December 2020

Natural products as sources of new drugs over the last 25 years

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12 December 2020

Natural products as leads to potential drugs: an old process or the new hope for drug discovery?

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12 December 2020

Design and synthesis of redox stable analogues of sunflower trypsin inhibitors (SFTI-1) on solid support, potent inhibitors of matriptase

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12 December 2020

Impact of natural products on developing new anti-cancer agents

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12 December 2020

A concise total synthesis of largazole, solution structure, and some preliminary structure activity relationships

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12 December 2020

Synthesis and histone deacetylase inhibitory activity of largazole analogs: alteration of the zinc-binding domain and macrocyclic scaffold

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12 December 2020

Enantioselective total synthesis of (+)-largazole, a potent inhibitor of histone deacetylase

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12 December 2020

Total synthesis and molecular target of largazole, a histone deacetylase inhibitor

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12 December 2020

Synthesis and activity of largazole analogues with linker and macrocycle modification

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12 December 2020

Chemistry. The renaissance of natural products as drug candidates

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12 December 2020

Total Solid-Phase Synthesis of Marine Cyclodepsipeptide IB-01212

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12 December 2020

An HPLC-ESMS study on the solid-phase assembly ofC-terminal proline peptides

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12 December 2020

Synthesis and conformation-activity relationships of the peptide isosteres of FK228 and largazole

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12 December 2020

Identifiers

DOI

10.1021/OL100308A

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27 July 2017

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