(Q33534400)

English

Parallel multiplicative target screening against divergent bacterial replicases: identification of specific inhibitors with broad spectrum potential

scientific article

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Parallel multiplicative target screening against divergent bacterial replicases: identification of specific inhibitors with broad spectrum potential (English)

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Marcos T Oliveira

object named as

Marcos T Oliveira

8

0 references

author name string

H Garry Dallmann

1

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Oliver J Fackelmayer

2

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Guy Tomer

3

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Joe Chen

4

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Anna Wiktor-Becker

5

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Tracey Ferrara

6

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Casey Pope

7

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Peter M J Burgers

9

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Laurie S Kaguni

10

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Charles S McHenry

11

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

language of work or name

0 references

publication date

1 March 2010

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

49

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

2551-2562

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Late stage antibacterial drugs in the clinical pipeline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

The role of mitochondria in pharmacotoxicology: a reevaluation of an old, newly emerging topic.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Exchange of DNA polymerases at the replication fork of bacteriophage T7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Staphylococcus aureus helicase but not Escherichia coli helicase stimulates S. aureus primase activity and maintains initiation specificity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Dihydrofolate reductase inhibitors as antibacterial agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

CELLULAR DNA REPLICASES: Components and Dynamics at the Replication Fork

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Interaction between the T4 helicase-loading protein (gp59) and the DNA polymerase (gp43): a locking mechanism to delay replication during replisome assembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Bacterial topoisomerase inhibitors: quinolone and pyridone antibacterial agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Determination of selectivity and efficacy of fatty acid synthesis inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

DNA polymerase gamma, the mitochondrial replicase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Small molecule modulation of the human chromatid decatenation checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Competitive processivity-clamp usage by DNA polymerases during DNA replication and repair.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Chromosomal replicases as asymmetric dimers: studies of subunit arrangement and functional consequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Mechanism of loading the Escherichia coli DNA polymerase III beta sliding clamp on DNA. Bona fide primer/templates preferentially trigger the gamma complex to hydrolyze ATP and load the clamp

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

DNA replication in the third domain (of life).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Evidence that monastrol is an allosteric inhibitor of the mitotic kinesin Eg5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

An expanded view of bacterial DNA replication.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Evolution of DNA polymerase families: evidences for multiple gene exchange between cellular and viral proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Crystal structure of the processivity clamp loader gamma (gamma) complex of E. coli DNA polymerase III

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

ATP utilization by yeast replication factor C. I. ATP-mediated interaction with DNA and with proliferating cell nuclear antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

A simple, high-resolution method for establishing DNA binding affinity and sequence selectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

tau binds and organizes Escherichia coli replication through distinct domains. Partial proteolysis of terminally tagged tau to determine candidate domains and to assign domain V as the alpha binding domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

In vitro antimicrobial activities of novel anilinouracils which selectively inhibit DNA polymerase III of gram-positive bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

A robotics-based automated assay for inorganic and organic phosphates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

The DNA replication fork in eukaryotic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

The chi psi subunits of DNA polymerase III holoenzyme bind to single-stranded DNA-binding protein (SSB) and facilitate replication of an SSB-coated template

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Devoted to the lagging strand-the subunit of DNA polymerase III holoenzyme contacts SSB to promote processive elongation and sliding clamp assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Mitochondrial injury. Lessons from the fialuridine trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

An automated high throughput filtration assay: application to polymerase inhibitor identification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Fluorometric assay for DNA polymerases and reverse transcriptase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Coupling of a replicative polymerase and helicase: a tau-DnaB interaction mediates rapid replication fork movement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Kinetic analysis of nucleotide incorporation and misincorporation by Klenow fragment of Escherichia coli DNA polymerase I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

SB 205952, a novel semisynthetic monic acid analog with at least two modes of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

DNA polymerase III accessory proteins. I. holA and holB encoding delta and delta'.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Compilation, alignment, and phylogenetic relationships of DNA polymerases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Identification, isolation, and overexpression of the gene encoding the psi subunit of DNA polymerase III holoenzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Melting of a DNA helix terminus within the active site of a DNA polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Escherichia coli DNA polymerase III holoenzyme subunits alpha, beta, and gamma directly contact the primer-template

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Size classes of products synthesized processively by DNA polymerase III and DNA polymerase III holoenzyme of Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Proofreading by DNA polymerase III of Escherichia coli depends on cooperative interaction of the polymerase and exonuclease subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

The RNA primer synthesized by primase to initiate phage G4 DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Cloning of a functional replication origin of phage G4 into the genome of phage M13

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

A quantitative assay for bacterial RNA polymerases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

21 June 2018

Quinazolin-2-ylamino-quinazolin-4-ols as novel non-nucleoside inhibitors of bacterial DNA polymerase III.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

31 October 2018

Crystal structure of the catalytic alpha subunit of E. coli replicative DNA polymerase III.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

31 October 2018

Mechanism of loading the Escherichia coli DNA polymerase III sliding clamp: I. Two distinct activities for individual ATP sites in the gamma complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

31 October 2018

Development and use of a high-throughput bacterial DNA gyrase assay to identify mammalian topoisomerase II inhibitors with whole-cell anticancer activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

31 October 2018

PolC-type polymerase III of Streptococcus pyogenes and its use in screening for chemical inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

31 October 2018

The DNA polymerase III holoenzyme: an asymmetric dimeric replicative complex with leading and lagging strand polymerases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

31 October 2018

The DNA replication machine of a gram-positive organism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

31 October 2018

Biotin tagging deletion analysis of domain limits involved in protein-macromolecular interactions. Mapping the tau binding domain of the DNA polymerase III alpha subunit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

31 October 2018

Purification and cloning of a soluble ATP-diphosphohydrolase (apyrase) from potato tubers (Solanum tuberosum).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

31 October 2018

Size classes of products synthesized processively by two subassemblies of Escherichia coli DNA polymerase III holoenzyme.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2849275

31 October 2018

Trading places on DNA--a three-point switch underlies primer handoff from primase to the replicative DNA polymerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/20184361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The structure of T. aquaticus DNA polymerase III is distinct from eukaryotic replicative DNA polymerases

1 reference

https://pubmed.ncbi.nlm.nih.gov/20184361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the beta-binding domain of the alpha subunit of Escherichia coli polymerase III holoenzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/20184361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical characterization and purification of the beta subunit of the DNA polymerase III holoenzyme from an overproducing strain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20184361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A New Method for the Large Scale Purification of Escherichia coli Deoxyribonucleic Acid-dependent Ribonucleic Acid Polymerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/20184361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A homogeneous, high-throughput fluorescence resonance energy transfer-based DNA polymerase assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/20184361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate overcomes the salt inhibition of DNA polymerase III holoenzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/20184361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A homogeneous method to measure aminoacyl-tRNA synthetase aminoacylation activity using scintillation proximity assay technology

1 reference

https://pubmed.ncbi.nlm.nih.gov/20184361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of the beta subunit of the DNA polymerase III holoenzyme of Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/20184361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and antimicrobial activity of some bis-quinazoline derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/20184361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo assembly of overproduced DNA polymerase III. Overproduction, purification, and characterization of the alpha, alpha-epsilon, and alpha-epsilon-theta subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/20184361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A method to assay inhibitors of DNA polymerase IIIC activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20184361

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/BI9020764

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q33534400&oldid=1599215049"