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pRb and E2f-1 in mouse development and tumorigenesis
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10072353
retrieved
27 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
pRb and E2f-1 in mouse development and tumorigenesis
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10072353
retrieved
27 July 2017
author name string
Macleod K
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10072353
retrieved
27 July 2017
publication date
1 February 1999
1 reference
stated in
Europe PubMed Central
PubMed ID
10072353
retrieved
27 July 2017
published in
Current Opinion in Genetics & Development
1 reference
stated in
Europe PubMed Central
PubMed ID
10072353
retrieved
27 July 2017
volume
9
1 reference
stated in
Europe PubMed Central
PubMed ID
10072353
retrieved
27 July 2017
page(s)
31-39
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stated in
Europe PubMed Central
PubMed ID
10072353
retrieved
27 July 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10072353
retrieved
27 July 2017
cites work
The regulation of E2F by pRB-family proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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The retinoblastoma gene family: cousins with overlapping interests.
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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An E2F-like repressor of transcription.
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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E2F-6, a member of the E2F family that can behave as a transcriptional repressor
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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PPARgamma induces cell cycle withdrawal: inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A.
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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E2F activity is regulated by cell cycle-dependent changes in subcellular localization
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Retinoblastoma protein recruits histone deacetylase to repress transcription
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Retinoblastoma protein represses transcription by recruiting a histone deacetylase
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Rb interacts with histone deacetylase to repress transcription
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Distinct roles for E2F proteins in cell growth control and apoptosis
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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Effects of an Rb mutation in the mouse
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Requirement for a functional Rb-1 gene in murine development
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Targeted disruption of p107: functional overlap between p107 and Rb
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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Shared role of the pRB-related p130 and p107 proteins in limb development
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
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The retinoblastoma gene family is differentially expressed during embryogenesis.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Tumor induction and tissue atrophy in mice lacking E2F-1
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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inferred from DOI database lookup
E2F-1 functions in mice to promote apoptosis and suppress proliferation
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Early loss of the retinoblastoma gene is associated with impaired growth inhibitory innervation during melanotroph carcinogenesis in Rb+/- mice.
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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p53-dependent apoptosis suppresses tumor growth and progression in vivo
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
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Oncogenic capacity of the E2F1 gene
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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E2F-1 blocks terminal differentiation and causes proliferation in transgenic megakaryocytes
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Flp-mediated tissue-specific inactivation of the retinoblastoma tumor suppressor gene in the mouse
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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Traps to catch unwary oncogenes
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
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ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
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Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
E1A signaling to p53 involves the p19(ARF) tumor suppressor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
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Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
p19ARF links the tumour suppressor p53 to Ras
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
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p14ARF links the tumour suppressors RB and p53.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
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E2F3 activity is regulated during the cell cycle and is required for the induction of S phase.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
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E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of DNA synthesis and apoptosis are separable functions of E2F-1.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
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Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
p107 is a suppressor of retinoblastoma development in pRb-deficient mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of RNA polymerases I and III by the retinoblastoma protein: a mechanism for growth control?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980005-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0959-437X(99)80005-7
1 reference
stated in
Europe PubMed Central
PubMed ID
10072353
retrieved
27 July 2017
PubMed ID
10072353
1 reference
stated in
Europe PubMed Central
PubMed ID
10072353
retrieved
27 July 2017
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