(Q33551475)

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A non-Smad mechanism of fibroblast activation by transforming growth factor-beta via c-Abl and Egr-1: selective modulation by imatinib mesylate

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scholarly article

1 reference

Europe PubMed Central

28 July 2017

A non-Smad mechanism of fibroblast activation by transforming growth factor-beta via c-Abl and Egr-1: selective modulation by imatinib mesylate (English)

1 reference

Europe PubMed Central

28 July 2017

1 reference

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author name string

S Bhattacharyya

1

1 reference

Europe PubMed Central

28 July 2017

W Ishida

2

1 reference

Europe PubMed Central

28 July 2017

M Wu

3

1 reference

Europe PubMed Central

28 July 2017

M Wilkes

4

1 reference

Europe PubMed Central

28 July 2017

Y Mori

5

1 reference

Europe PubMed Central

28 July 2017

M Hinchcliff

6

1 reference

Europe PubMed Central

28 July 2017

E Leof

7

1 reference

Europe PubMed Central

28 July 2017

J Varga

8

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Europe PubMed Central

28 July 2017

language of work or name

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publication date

19 January 2009

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Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

28

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Europe PubMed Central

28 July 2017

10

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Europe PubMed Central

28 July 2017

1285-1297

1 reference

Europe PubMed Central

28 July 2017

https://scigraph.springernature.com/pub.10.1038/onc.2008.479

0 references

Smad-independent transforming growth factor-beta regulation of early growth response-1 and sustained expression in fibrosis: implications for scleroderma

1 reference

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21 June 2018

Molecular ablation of transforming growth factor beta signaling pathways by tyrosine kinase inhibition: the coming of a promising new era in the treatment of tissue fibrosis

1 reference

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Fibrosis in systemic sclerosis

1 reference

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Targeting the TGFbeta, endothelin-1 and CCN2 axis to combat fibrosis in scleroderma

1 reference

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Connective tissue growth factor/CCN2-null mouse embryonic fibroblasts retain intact transforming growth factor-beta responsiveness

1 reference

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Systemic sclerosis: a prototypic multisystem fibrotic disorder

1 reference

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Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis

1 reference

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Platelet-derived growth factor-beta receptor activation is essential for fibroblast and pericyte recruitment during cutaneous wound healing.

1 reference

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Transforming growth factor beta activation of c-Abl is independent of receptor internalization and regulated by phosphatidylinositol 3-kinase and PAK2 in mesenchymal cultures

1 reference

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21 June 2018

The early-immediate gene EGR-1 is induced by transforming growth factor-beta and mediates stimulation of collagen gene expression

1 reference

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Early growth response-1 in cardiovascular pathobiology

1 reference

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Smad transcription factors

1 reference

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Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-beta: implications for carcinogenesis.

1 reference

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21 June 2018

c-Abl regulates early growth response protein (EGR1) in response to oxidative stress

1 reference

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ABL oncogenes and phosphoinositide 3-kinase: mechanism of activation and downstream effectors

1 reference

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21 June 2018

Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo

1 reference

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21 June 2018

Recent advances in fibroblast signaling and biology in scleroderma

1 reference

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1 reference

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21 June 2018

Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis

1 reference

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21 June 2018

Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma

1 reference

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Regulation of PDGF and its receptors in fibrotic diseases

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Following the molecular pathways toward an understanding of the pathogenesis of systemic sclerosis

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Ets ternary complex transcription factors

1 reference

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Chronic Myeloid Leukemia — Advances in Biology and New Approaches to Treatment

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Biphasic role of TGF-beta1 in signal transduction and crosstalk

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In vitro studies of the combination of imatinib mesylate (Gleevec) and arsenic trioxide (Trisenox) in chronic myelogenous leukemia

1 reference

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1 reference

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p160 Bcr mediates platelet-derived growth factor activation of extracellular signal-regulated kinase in vascular smooth muscle cells

1 reference

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c-Cbl facilitates fibronectin matrix production by v-Abl-transformed NIH3T3 cells via activation of small GTPases

1 reference

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EGR1 target genes in prostate carcinoma cells identified by microarray analysis.

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The c-Abl tyrosine kinase contributes to the transient activation of MAP kinase in cells plated on fibronectin

1 reference

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JAK-STAT signaling activated by Abl oncogenes

1 reference

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Cycling, stressed-out and nervous: cellular functions of c-Abl

1 reference

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1 reference

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Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway.

1 reference

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Functional interaction between DNA-PK and c-Abl in response to DNA damage

1 reference

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1 reference

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Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic-nuclear transport

1 reference

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Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

1 reference

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1 reference

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1 reference

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12 December 2020

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10.1038/ONC.2008.479

1 reference

Europe PubMed Central

28 July 2017

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1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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