(Q43848062)

27 November 2017

The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling (English)

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27 November 2017

T Virolle

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27 November 2017

E D Adamson

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27 November 2017

V Baron

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27 November 2017

D Birle

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27 November 2017

D Mercola

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27 November 2017

T Mustelin

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27 November 2017

I de Belle

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27 November 2017

1 December 2001

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27 November 2017

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27 November 2017

3

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27 November 2017

1124-1128

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27 November 2017

12

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https://scigraph.springernature.com/pub.10.1038/ncb1201-1124

27 November 2017

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cites work

PTEN: life as a tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

Deletion of PTEN in a patient with Bannayan-Riley-Ruvalcaba syndrome suggests allelism with Cowden disease

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

Germline mutations in PTEN are present in Bannayan-Zonana syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

The tumor suppressor PTEN regulates T cell survival and antigen receptor signaling by acting as a phosphatidylinositol 3-phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

PTEN induces apoptosis and cell cycle arrest through phosphoinositol-3-kinase/Akt-dependent and -independent pathways

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

Expression of PTEN in PTEN-deficient multiple myeloma cells abolishes tumor growth in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

Decreased Egr-1 expression in human, mouse and rat mammary cells and tissues correlates with tumor formation

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

The transcription factor EGR-1 suppresses transformation of human fibrosarcoma HT1080 cells by coordinated induction of transforming growth factor-beta1, fibronectin, and plasminogen activator inhibitor-1.

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

p53 and Egr-1 additively suppress transformed growth in HT1080 cells but Egr-1 counteracts p53-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

Ionizing radiation-inducible apoptosis in the absence of p53 linked to transcription factor EGR-1

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

EGR-1 induction is required for maximal radiosensitivity in A375-C6 melanoma cells

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

UV activates growth factor receptors via reactive oxygen intermediates

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

Method for cloning in vivo targets of the Egr-1 transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1)

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

1 reference

https://api.crossref.org/works/10.1038%2FNCB1201-1124

7 January 2021

Identifiers

DOI

10.1038/NCB1201-1124

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Dimensions Publication ID

27 November 2017

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