(Q33558189)

English

Activated factor X signaling via protease-activated receptor 2 suppresses pro-inflammatory cytokine production from lipopolysaccharide-stimulated myeloid cells

scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Activated factor X signaling via protease-activated receptor 2 suppresses pro-inflammatory cytokine production from lipopolysaccharide-stimulated myeloid cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

0 references

lipopolysaccharide

0 references

coagulation factor x human

1 reference

based on heuristic

inferred from title

object named as

Emily Hams

3

0 references

James S O'Donnell

object named as

James S O'Donnell

2

0 references

Padraic G. Fallon

object named as

Padraic G Fallon

6

0 references

author name string

Eimear M Gleeson

1

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Fionnuala Ní Áinle

4

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Bridget-Ann Kenny

5

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Roger J S Preston

7

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

19 July 2013

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

99

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

185-193

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Determinants of the specificity of protease-activated receptors 1 and 2 signaling by factor Xa and thrombin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

A zymogen-like factor Xa variant corrects the coagulation defect in hemophilia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

The hydroxylase inhibitor dimethyloxallyl glycine attenuates endotoxic shock via alternative activation of macrophages and IL-10 production by B1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

Proteinase-activated receptor 2 activation promotes an anti-inflammatory and alternatively activated phenotype in LPS-stimulated murine macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

Factor X/Xa elicits protective signaling responses in endothelial cells directly via PAR-2 and indirectly via endothelial protein C receptor-dependent recruitment of PAR-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

Activated protein C targets CD8+ dendritic cells to reduce the mortality of endotoxemia in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

The efficacy of activated protein C in murine endotoxemia is dependent on integrin CD11b

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

Coagulation factor Xa cleaves protease-activated receptor-1 and mediates signaling dependent on binding to the endothelial protein C receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

Factor Xa binding to annexin 2 mediates signal transduction via protease-activated receptor 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

Acute inflammation is exacerbated in mice genetically predisposed to a severe protein C deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

Modulation of monocyte function by activated protein C, a natural anticoagulant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

Innate sensors of microbial infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

Protease-activated receptors-1 and -2 can mediate endothelial barrier protection: role in factor Xa signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

Efficacy and safety of recombinant human activated protein C for severe sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

The elusive factor Xa receptor: failure to detect transcripts that correspond to the published sequence of EPR-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

Hypotension and inflammatory cytokine gene expression triggered by factor Xa-nitric oxide signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

Activation-dependent exposure of the inter-EGF sequence Leu83-Leu88 in factor Xa mediates ligand binding to effector cell protease receptor-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

The saturable high affinity association of factor X to ADP-stimulated monocytes defines a novel function of the Mac-1 receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

Identification of effector cell protease receptor-1. A leukocyte-distributed receptor for the serine protease factor Xa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

Lethal E. coli septic shock is prevented by blocking tissue factor with monoclonal antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

Septic shock, multiple organ failure, and disseminated intravascular coagulation. Compared patterns of antithrombin III, protein C, and protein S deficiencies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

21 June 2018

Factor X Deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

31 October 2018

Non-hematopoietic EPCR regulates the coagulation and inflammatory responses during endotoxemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

31 October 2018

Protease-activated receptor-1 signaling by activated protein C in cytokine-perturbed endothelial cells is distinct from thrombin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

31 October 2018

PI3K-Akt pathway suppresses coagulation and inflammation in endotoxemic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

31 October 2018

Genetic evidence that protease-activated receptors mediate factor Xa signaling in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

31 October 2018

Dysfunction of Endothelial Protein C Activation in Severe Meningococcal Sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4007938

31 October 2018

Phosphatidylinositol 3-kinase as a mediator of TNF-induced NF-kappa B activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23872307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of lymphocytes, granulocytes and macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/23872307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune complex-induced human monocyte procoagulant activity. II. Cellular kinetics and metabolic requirements

1 reference

https://pubmed.ncbi.nlm.nih.gov/23872307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombin and factor Xa enhance the production of interleukin-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/23872307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the lipopolysaccharide (LPS)-binding protein/CD14 pathway in LPS induction of tissue factor expression in monocytic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23872307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective inhibitory effects of the anticoagulant activated protein C on the responses of human mononuclear phagocytes to LPS, IFN-gamma, or phorbol ester

1 reference

https://pubmed.ncbi.nlm.nih.gov/23872307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effector cell protease receptor-1 is a vascular receptor for coagulation factor Xa.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23872307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effector cell protease receptor-1, a platelet activation-dependent membrane protein, regulates prothrombinase-catalyzed thrombin generation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23872307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disseminated intravascular coagulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23872307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3324/HAEMATOL.2013.086918

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

ResearchGate publication ID

0 references

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