(Q33559116)

English

Pediatric phase I trial and pharmacokinetic study of MLN8237, an investigational oral selective small-molecule inhibitor of Aurora kinase A: a Children's Oncology Group Phase I Consortium study

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scholarly article

1 reference

Europe PubMed Central

28 July 2017

Pediatric phase I trial and pharmacokinetic study of MLN8237, an investigational oral selective small-molecule inhibitor of Aurora kinase A: a Children's Oncology Group Phase I Consortium study (English)

1 reference

Europe PubMed Central

28 July 2017

phase I clinical trial

0 references

pharmacokinetics

1 reference

based on heuristic

inferred from title

10

object named as

Susan M Blaney

1 reference

Europe PubMed Central

28 July 2017

author name string

Yael P Mossé

1

1 reference

Europe PubMed Central

28 July 2017

Emily Lipsitz

2

1 reference

Europe PubMed Central

28 July 2017

Elizabeth Fox

3

1 reference

Europe PubMed Central

28 July 2017

David T Teachey

4

1 reference

Europe PubMed Central

28 July 2017

John M Maris

5

1 reference

Europe PubMed Central

28 July 2017

Brenda Weigel

6

1 reference

Europe PubMed Central

28 July 2017

Peter C Adamson

7

1 reference

Europe PubMed Central

28 July 2017

Mark A Ingle

8

1 reference

Europe PubMed Central

28 July 2017

Charlotte H Ahern

9

1 reference

Europe PubMed Central

28 July 2017

language of work or name

0 references

publication date

17 September 2012

1 reference

Europe PubMed Central

28 July 2017

Clinical Cancer Research

1 reference

Europe PubMed Central

28 July 2017

18

1 reference

Europe PubMed Central

28 July 2017

6058-6064

1 reference

Europe PubMed Central

28 July 2017

21

1 reference

Europe PubMed Central

28 July 2017

A sensitive and selective liquid chromatography/tandem mass spectrometry method for determination of MLN8237 in human plasma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008248

21 June 2018

Aurora kinase A promotes ovarian tumorigenesis through dysregulation of the cell cycle and suppression of BRCA2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008248

21 June 2018

Initial testing of the aurora kinase A inhibitor MLN8237 by the Pediatric Preclinical Testing Program (PPTP).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008248

21 June 2018

Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008248

21 June 2018

Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008248

21 June 2018

Aurora kinase family: a new target for anticancer drug.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008248

21 June 2018

Aurora kinases as anticancer drug targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008248

21 June 2018

Targeted disruption of Aurora A causes abnormal mitotic spindle assembly, chromosome misalignment and embryonic lethality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008248

21 June 2018

Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008248

21 June 2018

The Aurora kinases: role in cell transformation and tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008248

21 June 2018

Mitotic kinases as regulators of cell division and its checkpoints

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008248

21 June 2018

New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008248

21 June 2018

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008248

21 June 2018

Drug development: portals of discovery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4008248

31 October 2018

Amplification/overexpression of a mitotic kinase gene in human bladder cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22988055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shortening the timeline of pediatric phase I trials: the rolling six design

1 reference

https://pubmed.ncbi.nlm.nih.gov/22988055

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1078-0432.CCR-11-3251

1 reference

Europe PubMed Central

28 July 2017

release_tyri46l54ba27jfejxvvh5pxfm

1 reference

https://api.fatcat.wiki/v0/release/tyri46l54ba27jfejxvvh5pxfm

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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