(Q33567000)

English

Triptolide induces cell-cycle arrest and apoptosis of human multiple myeloma cells in vitro via altering expression of histone demethylase LSD1 and JMJD2B.

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scholarly article

1 reference

Europe PubMed Central

28 July 2017

Triptolide induces cell-cycle arrest and apoptosis of human multiple myeloma cells in vitro via altering expression of histone demethylase LSD1 and JMJD2B. (English)

1 reference

Europe PubMed Central

28 July 2017

multiple myeloma

1 reference

based on heuristic

inferred from title

author name string

Lu Wen

1

1 reference

Europe PubMed Central

28 July 2017

Yan Chen

2

1 reference

Europe PubMed Central

28 July 2017

Ling-lan Zeng

3

1 reference

Europe PubMed Central

28 July 2017

Fei Zhao

4

1 reference

Europe PubMed Central

28 July 2017

Rui Li

5

1 reference

Europe PubMed Central

28 July 2017

Yuan Liu

6

1 reference

Europe PubMed Central

28 July 2017

Chun Zhang

7

1 reference

Europe PubMed Central

28 July 2017

publication date

28 November 2011

1 reference

Europe PubMed Central

28 July 2017

Acta Pharmacologica Sinica

1 reference

Europe PubMed Central

28 July 2017

33

1 reference

Europe PubMed Central

28 July 2017

1

1 reference

Europe PubMed Central

28 July 2017

109-119

1 reference

Europe PubMed Central

28 July 2017

https://scigraph.springernature.com/pub.10.1038/aps.2011.145

0 references

SPR-5 is a histone H3K4 demethylase with a role in meiotic double-strand break repair

1 reference

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21 June 2018

Epigenetic regulation of transposable element derived human gene promoters

1 reference

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21 June 2018

Reprogramming factor expression initiates widespread targeted chromatin remodeling

1 reference

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Open, repair and close again: chromatin dynamics and the response to UV-induced DNA damage

1 reference

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21 June 2018

DNA methylation alterations in multiple myeloma as a model for epigenetic changes in cancer

1 reference

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21 June 2018

MYEOV is a prognostic factor in multiple myeloma

1 reference

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21 June 2018

Synthesis and biological evaluation of novel triptolide analogues for anticancer activity

1 reference

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The histone demethylase JMJD2B is regulated by estrogen receptor alpha and hypoxia, and is a key mediator of estrogen induced growth

1 reference

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21 June 2018

Epigenetic regulation of cancer growth by histone demethylases

1 reference

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Lysine methylation regulates E2F1-induced cell death

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1 reference

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Role of triptolide in cell proliferation, cell cycle arrest, apoptosis and histone methylation in multiple myeloma U266 cells

1 reference

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21 June 2018

Effects of triptolide on RIZ1 expression, proliferation, and apoptosis in multiple myeloma U266 cells

1 reference

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21 June 2018

Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology

1 reference

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21 June 2018

Triptolide alters histone H3K9 and H3K27 methylation state and induces G0/G1 arrest and caspase-dependent apoptosis in multiple myeloma in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010266

21 June 2018

Histone H3 lysine 4 (H3K4) methylation in development and differentiation

1 reference

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21 June 2018

New roles of flavoproteins in molecular cell biology: histone demethylase LSD1 and chromatin

1 reference

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hSET1: a novel approach for colon cancer therapy

1 reference

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21 June 2018

Epigenetic silencing of the interferon regulatory factor ICSBP/IRF8 in human multiple myeloma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010266

21 June 2018

Triptolide cooperates with chemotherapy to induce apoptosis in acute myeloid leukemia cells.

1 reference

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21 June 2018

Triptolide overcomes dexamethasone resistance and enhanced PS-341-induced apoptosis via PI3k/Akt/NF-kappaB pathways in human multiple myeloma cells.

1 reference

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21 June 2018

Apoptosis of human pancreatic cancer cells induced by Triptolide

1 reference

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21 June 2018

Triptolide sensitizes AML cells to TRAIL-induced apoptosis via decrease of XIAP and p53-mediated increase of DR5.

1 reference

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Apoptosis, cell cycle progression and gene expression in TP53-depleted HCT116 colon cancer cells in response to short-term 5-fluorouracil treatment.

1 reference

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Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70.

1 reference

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The effect of triptolide on apoptosis of glioblastoma multiforme (GBM) cells

1 reference

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21 June 2018

Epigenetic dysregulation of Wnt signaling pathway in multiple myeloma

1 reference

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Chromatin remodeling and cancer, Part I: Covalent histone modifications

1 reference

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21 June 2018

p53 is regulated by the lysine demethylase LSD1

1 reference

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The new frontier in cancer research: deciphering cancer epigenetics.

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Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

1 reference

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Inhibitory effect of triptolide on lymph node metastasis in patients with non-Hodgkin lymphoma by regulating SDF-1/CXCR4 axis in vitro

1 reference

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Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells

1 reference

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Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells

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LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription

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Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin

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Triptolide down-regulates bcr-abl expression and induces apoptosis in chronic myelogenous leukemia cells

1 reference

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Triptolide inhibits the growth and metastasis of solid tumors.

1 reference

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Antiproliferative and proapoptotic activities of triptolide (PG490), a natural product entering clinical trials, on primary cultures of human prostatic epithelial cells

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1 reference

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1 reference

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Efficient migration of dendritic cells toward lymph node chemokines and induction of T(H)1 responses require maturation stimulus and apoptotic cell interaction.

1 reference

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Triptolide inhibits transcription factor NF-kappaB and induces apoptosis of multiple myeloma cells

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2011.145

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Conserved antagonism between JMJD2A/KDM4A and HP1γ during cell cycle progression.

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2011.145

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DNA methylation changes in multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22120968

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https://pubmed.ncbi.nlm.nih.gov/22120968

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22120968

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Identifiers

10.1038/APS.2011.145

1 reference

Europe PubMed Central

28 July 2017

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1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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