(Q37796732)

23 August 2017

title

DNA methylation alterations in multiple myeloma as a model for epigenetic changes in cancer (English)

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23 August 2017

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6

John M Greally

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23 August 2017

Amy Sharma

1

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23 August 2017

Christoph J Heuck

2

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23 August 2017

Melissa J Fazzari

3

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23 August 2017

Jayesh Mehta

4

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23 August 2017

Seema Singhal

5

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23 August 2017

Amit Verma

7

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23 August 2017

publication date

1 November 2010

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Wiley interdisciplinary reviews. Systems biology and medicine

23 August 2017

published in

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23 August 2017

volume

2

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23 August 2017

issue

6

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23 August 2017

page(s)

654-669

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Epigenomics: beyond CpG islands.

23 August 2017

cites work

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21 January 2018

CpG islands and genes

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

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Histone acetylation and chromatin signature in stem cell identity and cancer

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Phylogenomics of the nucleosome

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Translating the Histone Code

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The language of covalent histone modifications

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Histone methylation in transcriptional control

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Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails

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Histone and chromatin cross-talk

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Histone methylation and ubiquitination with their cross-talk and roles in gene expression and stability

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A chromatin landmark and transcription initiation at most promoters in human cells

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DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

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Linking DNA methylation and histone modification: patterns and paradigms

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DNA methylation models histone acetylation

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MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

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Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer.

21 January 2018

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Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

21 January 2018

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The epigenomics of cancer

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MicroRNAs: small RNAs with a big role in gene regulation

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MiRNAs, epigenetics, and cancer

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MicroRNAs: target recognition and regulatory functions

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Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

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Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

21 January 2018

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miRNAs, cancer, and stem cell division

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Genetic unmasking of an epigenetically silenced microRNA in human cancer cells

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MicroRNA expression profiles classify human cancers

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Antisense transcription in the mammalian transcriptome

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Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

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Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease

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Human DNA methyltransferase 1 is required for maintenance of the histone H3 modification pattern

21 January 2018

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Hypomethylation distinguishes genes of some human cancers from their normal counterparts

21 January 2018

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Cytosine methylation and human cancer

21 January 2018

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The history of cancer epigenetics

21 January 2018

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DNA methylation changes and multiple myeloma

21 January 2018

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Transposons reanimated in mice

21 January 2018

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21 January 2018

Epigenetics in cancer

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The new frontier in cancer research: deciphering cancer epigenetics.

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Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma

21 January 2018

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Molecular aspects of multiple myeloma.

21 January 2018

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Multiple myeloma: a review of the epidemiologic literature

21 January 2018

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DNA-methylation analysis identifies the E-cadherin gene as a potential marker of disease progression in patients with monoclonal gammopathies

21 January 2018

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Disruption of INK4/CDK/Rb cell cycle pathway by gene hypermethylation in multiple myeloma and MGUS.

21 January 2018

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Methylation profiling in multiple myeloma.

21 January 2018

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Tumor suppressor p16 methylation in multiple myeloma: biological and clinical implications

21 January 2018

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Aberrant gene methylation implicated in the progression of monoclonal gammopathy of undetermined significance to multiple myeloma

21 January 2018

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Decitabine induces cell cycle arrest at the G1 phase via p21(WAF1) and the G2/M phase via the p38 MAP kinase pathway

21 January 2018

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Epigenetic dysregulation of the death-associated protein kinase/p14/HDM2/p53/Apaf-1 apoptosis pathway in multiple myeloma.

21 January 2018

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SOCS1 and SHP1 hypermethylation in multiple myeloma: implications for epigenetic activation of the Jak/STAT pathway

21 January 2018

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SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma

21 January 2018

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Differential methylation of genes that regulate cytokine signaling in lymphoid and hematopoietic tumors

21 January 2018

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High-frequency promoter hypermethylation of the deleted in liver cancer-1 gene in multiple myeloma

21 January 2018

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Reversal of p53 epigenetic silencing in multiple myeloma permits apoptosis by a p53 activator

21 January 2018

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Methylation status of fragile histidine triad (FHIT) gene and its clinical impact on prognosis of patients with multiple myeloma

21 January 2018

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Down-regulation of PU.1 by methylation of distal regulatory elements and the promoter is required for myeloma cell growth.

21 January 2018

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ABCG2 expression, function, and promoter methylation in human multiple myeloma

21 January 2018

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Aberrant DNA methylation associated with silencing BNIP3 gene expression in haematopoietic tumours.

21 January 2018

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SPAN-Xb expression in myeloma cells is dependent on promoter hypomethylation and can be upregulated pharmacologically

21 January 2018

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Epigenetic silencing of the human nucleotide excision repair gene, hHR23B, in interleukin-6-responsive multiple myeloma KAS-6/1 cells

21 January 2018

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DNA hypermethylation and partial gene silencing of human thymine- DNA glycosylase in multiple myeloma cell lines

21 January 2018

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Epigenetic dysregulation of Wnt signaling pathway in multiple myeloma

21 January 2018

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Epigenetic silencing of manganese superoxide dismutase (SOD-2) in KAS 6/1 human multiple myeloma cells increases cell proliferation

21 January 2018

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Promoter hypermethylation of tetraspanin members contributes to their silencing in myeloma cell lines

21 January 2018

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Overexpression of the NOTCH ligand JAG2 in malignant plasma cells from multiple myeloma patients and cell lines.

21 January 2018

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Recombinant Human DNA (Cytosine-5) Methyltransferase

21 January 2018

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

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Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation

21 January 2018

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5-Azacytidine, a DNA methyltransferase inhibitor, induces ATR-mediated DNA double-strand break responses, apoptosis, and synergistic cytotoxicity with doxorubicin and bortezomib against multiple myeloma cells.

21 January 2018

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Genome-wide transcriptional response to 5-aza-2'-deoxycytidine and trichostatin a in multiple myeloma cells.

21 January 2018

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Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies

21 January 2018

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An integrative genomic and epigenomic approach for the study of transcriptional regulation

21 January 2018

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MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation

21 January 2018

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Microarray analysis of epigenetic silencing of gene expression in the KAS-6/1 multiple myeloma cell line

21 January 2018

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High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing

21 January 2018

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Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells

21 January 2018

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Comprehensive high-throughput arrays for relative methylation (CHARM).

21 January 2018

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Comparative isoschizomer profiling of cytosine methylation: the HELP assay

21 January 2018

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Genome-wide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/T-lymphoid features.

21 January 2018

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Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells

21 January 2018

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Meta-analysis of microarray studies reveals a novel hematopoietic progenitor cell signature and demonstrates feasibility of inter-platform data integration

21 January 2018

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Mutagenic deamination of cytosine residues in DNA

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/WSBM.89

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23 August 2017

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