(Q33568637)

28 July 2017

SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism (English)

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28 July 2017

Alan E Friedman

6

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author name string

Hongwei Yao

1

1 reference

28 July 2017

Isaac K Sundar

2

1 reference

28 July 2017

Tanveer Ahmad

3

1 reference

28 July 2017

Chad Lerner

4

1 reference

28 July 2017

Janice Gerloff

5

1 reference

28 July 2017

Richard P Phipps

7

1 reference

28 July 2017

Patricia J Sime

8

1 reference

28 July 2017

Michael W McBurney

9

1 reference

28 July 2017

Leonard Guarente

10

1 reference

28 July 2017

Irfan Rahman

11

1 reference

28 July 2017

14 March 2014

1 reference

American Journal of Physiology - Lung Cellular and Molecular Physiology

28 July 2017

1 reference

28 July 2017

306

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28 July 2017

9

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28 July 2017

L816-28

1 reference

describes a project that uses

28 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4010647/fullTextXML

inferred from PubMed Central ID database lookup

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Circadian clock function is disrupted by environmental tobacco/cigarette smoke, leading to lung inflammation and injury via a SIRT1-BMAL1 pathway

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21 June 2018

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21 June 2018

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Nrf2 is not required for epithelial prohibitin-dependent attenuation of experimental colitis

21 June 2018

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21 June 2018

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SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice

21 June 2018

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21 June 2018

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Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin

21 June 2018

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SIRT1 as a therapeutic target in inflammaging of the pulmonary disease

21 June 2018

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Lung glutathione adaptive responses to cigarette smoke exposure

21 June 2018

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FOXO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary disease

21 June 2018

1 reference

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Oxidative DNA damage in lung tissue from patients with COPD is clustered in functionally significant sequences

21 June 2018

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Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease

21 June 2018

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Acetylation-deacetylation of the transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) regulates its transcriptional activity and nucleocytoplasmic localization

21 June 2018

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Nrf2 deficiency influences susceptibility to steroid resistance via HDAC2 reduction

21 June 2018

1 reference

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Manganese superoxide dismutase expression in endothelial progenitor cells accelerates wound healing in diabetic mice

21 June 2018

1 reference

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Extracellular superoxide dismutase protects against pulmonary emphysema by attenuating oxidative fragmentation of ECM.

21 June 2018

1 reference

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Heme oxygenase-1 inhibits renal tubular macroautophagy in acute kidney injury

21 June 2018

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Redox regulation of sirtuin-1 by S-glutathiolation.

21 June 2018

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SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress

21 June 2018

1 reference

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NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector

21 June 2018

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A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders

21 June 2018

1 reference

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Lipid peroxidation products as oxidative stress biomarkers

21 June 2018

1 reference

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A protein deacetylase SIRT1 is a negative regulator of metalloproteinase-9.

21 June 2018

1 reference

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Cigarette smoke-induced emphysema in A/J mice is associated with pulmonary oxidative stress, apoptosis of lung cells, and global alterations in gene expression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Oxidative damage to nucleic acids in severe emphysema

21 June 2018

1 reference

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Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

SIRT1 transgenic mice show phenotypes resembling calorie restriction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Foxo3 is required for the regulation of oxidative stress in erythropoiesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Alpha,beta-unsaturated aldehydes in cigarette smoke release inflammatory mediators from human macrophages

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Oxidative stress and redox regulation of lung inflammation in COPD.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Functional variants of antioxidant genes in smokers with COPD and in those with normal lung function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Pulmonary and systemic oxidant/antioxidant imbalance in chronic obstructive pulmonary disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Focus on antioxidant enzymes and antioxidant strategies in smoking related airway diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Oxidative stress in pathogenesis of chronic obstructive pulmonary disease: cellular and molecular mechanisms

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Covalent modification of amino acid nucleophiles by the lipid peroxidation products 4-hydroxy-2-nonenal and 4-oxo-2-nonenal

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Oxidative stress and regulation of glutathione in lung inflammation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Probability-based protein identification by searching sequence databases using mass spectrometry data

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Oxidants and antioxidants as therapeutic targets in chronic obstructive pulmonary disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Oxidative Stress in Chronic Obstructive Pulmonary Disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Role of oxidants/antioxidants in smoking-induced lung diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Free-radical chemistry of cigarette smoke and its toxicological implications

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Sirt1 resists advanced glycation end products-induced expressions of fibronectin and TGF-β1 by activating the Nrf2/ARE pathway in glomerular mesangial cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Lung function loss, smoking, vitamin C intake, and polymorphisms of the glutamate-cysteine ligase genes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Cigarette smoke-mediated inflammatory and oxidative responses are strain-dependent in mice.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Polymorphisms and functional activity in superoxide dismutase and catalase genes in smokers with COPD.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Sirt1 regulates aging and resistance to oxidative stress in the heart

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Genetically increased antioxidative protection and decreased chronic obstructive pulmonary disease

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Elevated urinary 8-hydroxydeoxyguanosine, a biomarker of oxidative stress, and lack of association with antioxidant vitamins in chronic obstructive pulmonary disease

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Antioxidant gene polymorphisms and susceptibility to a rapid decline in lung function in smokers

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Role of NRF2 in protection against hyperoxic lung injury in mice

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Epithelial Permeability, Inflammation, and Oxidant Stress in the Air Spaces of Smokers

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Systemic oxidative stress in asthma, COPD, and smokers

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4010647

Induction of γ-glutamylcysteine synthetase by cigarette smoke is associated with AP-1 in human alveolar epithelial cells

31 October 2018

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12 December 2020

Increase in reactive nitrogen species production in chronic obstructive pulmonary disease airways

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12 December 2020

Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method

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12 December 2020

Chemical nature of stochastic generation of protein-based carbonyls: metal-catalyzed oxidation versus modification by products of lipid oxidation

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12 December 2020

10.1152/AJPLUNG.00323.2013

Identifiers

DOI

1 reference

28 July 2017

1 reference

28 July 2017

1 reference