(Q33572392)

28 July 2017

title

Hedonic Homeostatic Dysregulation as a Driver of Drug-Seeking Behavior (English)

1 reference

28 July 2017

1

George F Koob

1 reference

28 July 2017

publication date

1 January 2008

1 reference

Drug discovery today. Disease models

28 July 2017

published in

1 reference

28 July 2017

volume

5

1 reference

28 July 2017

issue

4

1 reference

28 July 2017

page(s)

207-215

1 reference

Corticotropin-releasing factor-1 receptor antagonists decrease heroin self-administration in long- but not short-access rats

28 July 2017

cites work

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21 June 2018

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21 June 2018

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The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid system

21 June 2018

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21 June 2018

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CRF(1) receptor antagonists attenuate escalated cocaine self-administration in rats

21 June 2018

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CRF-CRF1 system activation mediates withdrawal-induced increases in nicotine self-administration in nicotine-dependent rats

21 June 2018

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Alpha 1-noradrenergic system role in increased motivation for cocaine intake in rats with prolonged access

21 June 2018

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Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence

21 June 2018

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Effect of aripiprazole, a partial dopamine D2 receptor agonist, on increased rate of methamphetamine self-administration in rats with prolonged session duration

21 June 2018

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The gamma-aminobutyric acid-B receptor agonist baclofen attenuates responding for ethanol in ethanol-dependent rats

21 June 2018

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Brain reward deficits accompany withdrawal (hangover) from acute ethanol in rats

21 June 2018

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Corticotropin-releasing factor 1 antagonists selectively reduce ethanol self-administration in ethanol-dependent rats

21 June 2018

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21 June 2018

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The corticotropin-releasing factor receptor-1 pathway mediates the negative affective states of opiate withdrawal.

21 June 2018

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Behavioral and neural mechanisms of compulsive drug seeking

21 June 2018

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The dopamine hypothesis of drug addiction: hypodopaminergic state.

21 June 2018

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The amygdala and persistent pain

21 June 2018

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Buprenorphine and a CRF1 antagonist block the acquisition of opiate withdrawal-induced conditioned place aversion in rats

21 June 2018

1 reference

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Historical review: Molecular and cellular mechanisms of opiate and cocaine addiction

21 June 2018

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Role of dopamine in drug reinforcement and addiction in humans: results from imaging studies

21 June 2018

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Compulsive drug-seeking behavior and relapse. Neuroadaptation, stress, and conditioning factors.

21 June 2018

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21 June 2018

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21 June 2018

1 reference

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Corticotropin-releasing factor antagonist attenuates the "anxiogenic-like" effect in the defensive burying paradigm but not in the elevated plus-maze following chronic cocaine in rats

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801885

In vivo CRF release in rat amygdala is increased during cocaine withdrawal in self-administering rats

21 June 2018

1 reference

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Transition from moderate to excessive drug intake: change in hedonic set point.

21 June 2018

1 reference

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Drug abuse: hedonic homeostatic dysregulation

21 June 2018

1 reference

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Activation of corticotropin-releasing factor in the limbic system during cannabinoid withdrawal

21 June 2018

1 reference

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kappa-Opioid agonist, U50,488H, stimulates ovine fetal pituitary-adrenal function via hypothalamic arginine-vasopressin and corticotrophin-releasing factor.

21 June 2018

1 reference

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Increase of extracellular corticotropin-releasing factor-like immunoreactivity levels in the amygdala of awake rats during restraint stress and ethanol withdrawal as measured by microdialysis.

21 June 2018

1 reference

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An opponent-process theory of motivation: I. Temporal dynamics of affect.

21 June 2018

1 reference

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Psychotomimesis mediated by kappa opiate receptors

21 June 2018

1 reference

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Motivational properties of kappa and mu opioid receptor agonists studied with place and taste preference conditioning

21 June 2018

1 reference

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Cellular and molecular mechanisms of drug dependence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801885

Neurobiology of opiate abuse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801885

Marked inhibition of mesolimbic dopamine release: a common feature of ethanol, morphine, cocaine and amphetamine abstinence in rats

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801885

Euphorigenic drugs: effects on the reward pathways of the brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801885

Kappa agonist-induced reinstatement of cocaine seeking in squirrel monkeys: a role for opioid and stress-related mechanisms

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801885

Conditioned withdrawal drives heroin consumption and decreases reward sensitivity.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801885

Escalation of methamphetamine self-administration in rats: a dose-effect function.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801885

Plasticity of reward neurocircuitry and the 'dark side' of drug addiction

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801885

Enhanced alcohol self-administration after intermittent versus continuous alcohol vapor exposure

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801885

Brain reward deficits accompany naloxone-precipitated withdrawal from acute opioid dependence

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801885

Drug seeking becomes compulsive after prolonged cocaine self-administration.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801885

Increased motivation for self-administered cocaine after escalated cocaine intake

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801885

Low dose cocaine self-administration transiently increases but high dose cocaine persistently decreases brain reward function in rats

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801885

Increased ethanol self-administration and anxiety-like behavior during acute ethanol withdrawal and protracted abstinence: regulation by corticotropin-releasing factor

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801885

Neurobiological evidence for hedonic allostasis associated with escalating cocaine use.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801885

Microinjection of a corticotropin-releasing factor antagonist into the central nucleus of the amygdala reverses anxiogenic-like effects of ethanol withdrawal

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801885

Noradrenaline in the ventral forebrain is critical for opiate withdrawal-induced aversion

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20054425

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Persistent increase in the motivation to take heroin in rats with a history of drug escalation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20054425

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/20054425

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.DDMOD.2009.04.002

1 reference

28 July 2017

1 reference

28 July 2017

1 reference