(Q33575159)

28 July 2017

title

GABAB agonism promotes sleep and reduces cataplexy in murine narcolepsy (English)

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28 July 2017

0 references

1 reference

Sarah Wurts Black

1

1 reference

28 July 2017

Stephen R Morairty

2

1 reference

28 July 2017

Tsui-Ming Chen

3

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28 July 2017

Andrew K Leung

4

1 reference

28 July 2017

Jonathan P Wisor

5

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28 July 2017

Akihiro Yamanaka

6

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28 July 2017

Thomas S Kilduff

7

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28 July 2017

language of work or name

English

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publication date

1 May 2014

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28 July 2017

published in

Journal of Neuroscience

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28 July 2017

volume

34

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28 July 2017

issue

19

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28 July 2017

page(s)

6485-6494

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Conditional ablation of orexin/hypocretin neurons: a new mouse model for the study of narcolepsy and orexin system function

28 July 2017

cites work

1 reference

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Influence of inhibitory serotonergic inputs to orexin/hypocretin neurons on the diurnal rhythm of sleep and wakefulness

21 June 2018

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Role of the medial prefrontal cortex in cataplexy.

21 June 2018

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Almorexant promotes sleep and exacerbates cataplexy in a murine model of narcolepsy

21 June 2018

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Reversal of disease-related pathologies in the fragile X mouse model by selective activation of GABAB receptors with arbaclofen.

21 June 2018

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Narcolepsy: neural mechanisms of sleepiness and cataplexy

21 June 2018

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Differential effects of sodium oxybate and baclofen on EEG, sleep, neurobehavioral performance, and memory

21 June 2018

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α4βδ GABA(A) receptors are high-affinity targets for γ-hydroxybutyric acid (GHB)

21 June 2018

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Possible long-term effects of γ-hydroxybutyric acid (GHB) due to neurotoxicity and overdose

21 June 2018

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Psychosis in the context of sodium oxybate therapy

21 June 2018

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Narcolepsy and effectiveness of gamma-hydroxybutyrate (GHB): a systematic review and meta-analysis of randomized controlled trials

21 June 2018

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Subchronic administration and combination metabotropic glutamate and GABAB receptor drug therapy in fragile X syndrome

21 June 2018

1 reference

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Connectomics of orexin-producing neurons: interface of systems of emotion, energy homeostasis and arousal

21 June 2018

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A review of sodium oxybate and baclofen in the treatment of sleep disorders

21 June 2018

1 reference

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Orexin/hypocretin plays a role in the response to physiological disequilibrium

21 June 2018

1 reference

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The nightly use of sodium oxybate is associated with a reduction in nocturnal sleep disruption: a double-blind, placebo-controlled study in patients with narcolepsy.

21 June 2018

1 reference

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Differential effects of GABAB receptor subtypes, {gamma}-hydroxybutyric Acid, and Baclofen on EEG activity and sleep regulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

Enhancing slow wave sleep with sodium oxybate reduces the behavioral and physiological impact of sleep loss.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

Narcolepsy and depression and the neurobiology of gammahydroxybutyrate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

GABA(B) receptors in drug addiction.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

A consensus definition of cataplexy in mouse models of narcolepsy.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

Increased GABA levels in medial prefrontal cortex of young adults with narcolepsy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

Running promotes wakefulness and increases cataplexy in orexin knockout mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

Reduced number of hypocretin neurons in human narcolepsy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

Simultaneous stimulation of slow-wave sleep and growth hormone secretion by gamma-hydroxybutyrate in normal young Men.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

Effect of baclofen on sleep-related periodic leg movements.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

Ontogeny of gamma-hydroxybutyric acid. II. Electroencephalographic effects.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

GABA(B) receptors play an essential role in maintaining sleep during the second half of the night in Drosophila melanogaster

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

γ-Hydroxybutyric acid induces actions via the GABAB receptor in arousal and motor control-related nuclei: implications for therapeutic actions in behavioral state disorders.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

Abnormal activity in reward brain circuits in human narcolepsy with cataplexy.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

Narcolepsy: action of two gamma-aminobutyric acid type B agonists, baclofen and sodium oxybate.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

The distribution of gamma-hydroxybutyrate-induced Fos expression in rat brain: comparison with baclofen

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

Activation of pedunculopontine tegmental PKA prevents GABAB receptor activation-mediated rapid eye movement sleep suppression in the freely moving rat.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

Cataleptic effects of gamma-hydroxybutyrate (GHB), its precursor gamma-butyrolactone (GBL), and GABAB receptor agonists in mice: differential antagonism by the GABAB receptor antagonist CGP35348.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

Effects of gamma-hydroxybutyrate (GHB) on vigilance states and EEG in mice

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

Bi-directional effects of GABA(B) receptor agonists on the mesolimbic dopamine system

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

Sleep is differently modulated by basal forebrain GABA(A) and GABA(B) receptors

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

GHB depresses fast excitatory and inhibitory synaptic transmission via GABA(B) receptors in mouse neocortical neurons.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

Hypocretin (orexin) deficiency in human narcolepsy.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012308

Effects of STX209 (arbaclofen) on neurobehavioral function in children and adults with fragile X syndrome: a randomized, controlled, phase 2 trial

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24806675

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1523/JNEUROSCI.0080-14.2014

1 reference

28 July 2017

1 reference

28 July 2017

1 reference