(Q33586646)

28 July 2017

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title

An overview of chemotherapeutic targets for antimalarial drug discovery (English)

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ORCID Public Data File 2021

28 July 2017

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author name string

Olliaro PL

series ordinal

1

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PubMed ID

10190581

28 July 2017

Yuthavong Y

series ordinal

2

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28 July 2017

1 February 1999

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Pharmacology & Therapeutics

28 July 2017

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28 July 2017

81

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28 July 2017

91-110

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28 July 2017

2

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The methionine synthesis cycle and salvage of methyltetrahydrofolate from host red cells in the malaria parasite (Plasmodium falciparum).

28 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Hexose-monophosphate shunt activity in intact Plasmodium falciparum-infected erythrocytes and in free parasites.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Inhibition of Plasmodium falciparum malaria using antisense oligodeoxynucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Point mutations in the dihydrofolate reductase-thymidylate synthase gene and pyrimethamine and cycloguanil resistance in Plasmodium falciparum.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Non-iron porphyrins inhibit beta-haematin (malaria pigment) polymerisation.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

A glutathione reductase-like flavoenzyme of the malaria parasite Plasmodium falciparum: structural considerations based on the DNA sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Characterization of iron-dependent endogenous superoxide dismutase of Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Reversal of chloroquine resistance in malaria parasite Plasmodium falciparum by desipramine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Bis(benzyl)polyamine analogs inhibit the growth of chloroquine-resistant human malaria parasites (Plasmodium falciparum) in vitro and in combination with alpha-difluoromethylornithine cure murine malaria

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Investigations of B- and beta-hematin

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Synthesis of beta-hematin by dehydrohalogenation of hemin.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Characterization of the products of the heme detoxification pathway in malarial late trophozoites by X-ray diffraction

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Rapid chloroquine efflux phenotype in both chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum. A correlation of chloroquine sensitivity with energy-dependent drug accumulation.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Recombinant Plasmodium falciparum dihydrofolate reductase-based in vitro screen for antifolate antimalarials.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Antimalarial drugs and the mosquito transmission of Plasmodium

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Expression of Plasmodium falciparum lactate dehydrogenase in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Iron chelators: mode of action as antimalarials

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

The catalytic mechanism and structure of thymidylate synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Cloning and characterization of subunit genes of ribonucleotide reductase, a cell-cycle-regulated enzyme, from Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Control of heme polymerase by chloroquine and other quinoline derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Ferriprotoporphyrin IX fulfills the criteria for identification as the chloroquine receptor of malaria parasites

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Thiostrepton binds to malarial plastid rRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

A P-glycoprotein homologue of Plasmodium falciparum is localized on the digestive vacuole

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Antimalarial activity of artemisinin (qinghaosu) and related trioxanes: mechanism(s) of action

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Sequence, expression and modeled structure of an aspartic proteinase from the human malaria parasite Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Inhibition of Plasmodium falciparum hypoxanthine-guanine phosphoribosyltransferase mRNA by antisense oligodeoxynucleotide sequence.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Pore size of the malaria parasite's nutrient channel

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

A nutrient-permeable channel on the intraerythrocytic malaria parasite

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Activity of fluoroquinolone antibiotics against Plasmodium falciparum in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Signal transduction in malaria parasites.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Synthesis and antimalarial effects of phenothiazine inhibitors of a Plasmodium falciparum cysteine protease

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Malarial haemozoin/beta-haematin supports haem polymerization in the absence of protein

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

The structure of lactate dehydrogenase from Plasmodium falciparum reveals a new target for anti-malarial design

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Quinoline anti-malarial drugs inhibit spontaneous formation of beta-haematin (malaria pigment).

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Use of radioactive ethanolamine incorporation into phospholipids to assess in vitro antimalarial activity by the semiautomated microdilution technique

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Phospholipid metabolism of serine in Plasmodium-infected erythrocytes involves phosphatidylserine and direct serine decarboxylation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Secretory transport in Plasmodium

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Malaria Parasites Adopt Host Cell Superoxide Dismutase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Oxidant defense enzymes of Plasmodium falciparum.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Molecular cloning and characterization of a putative glutathione reductase gene, the PfGR2 gene, from Plasmodium falciparum.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Molecular cloning and characterization of a second calcium-dependent protein kinase of Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

The 6-kb element of Plasmodium falciparum encodes mitochondrial cytochrome genes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

The extrachromosomal DNAs of apicomplexan parasites

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Plasmodium falciparum: alterations in organelle transcript abundance during the erythrocytic cycle.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Identification of additional rRNA fragments encoded by the Plasmodium falciparum 6 kb element

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

The mode of action and the mechanism of resistance to antimalarial drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Molecular characterization and inhibition of a Plasmodium falciparum aspartic hemoglobinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Biosynthesis and maturation of the malaria aspartic hemoglobinases plasmepsins I and II.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Site of action of the antimalarial hydroxynaphthoquinone, 2-[trans-4-(4'-chlorophenyl) cyclohexyl]-3- hydroxy-1,4-naphthoquinone (566C80)

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Effect of mitochondrial inhibitors on adenosinetriphosphate levels in Plasmodium falciparum.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Synthesis and in vitro evaluation of 9-anilino-3,6-diaminoacridines active against a multidrug-resistant strain of the malaria parasite Plasmodium falciparum.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Molecular characterization of the glutathione peroxidase gene of the human malaria parasite Plasmodium falciparum.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

A circular DNA in malaria parasites encodes an RNA polymerase like that of prokaryotes and chloroplasts

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Effects of Antibiotics on Plasmodium Falciparum in Vitro *

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Plasmodium falciparum: transport of entantiomers of nucleosides into Sendai-treated trophozoites

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Nutrient transport pathways in Plasmodium-infected erythrocytes: what and where are they?

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Altered membrane permeability: a new approach to malaria chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Dihydroorotate dehydrogenase, orotate phosphoribosyltransferase and orotidine-5′-phosphate decarboxylase in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Transport pathways in the malaria-infected erythrocyte. Their characterization and their use as potential targets for chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

The redox status of malaria-infected erythrocytes: an overview with an emphasis on unresolved problems

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Characterization of permeation pathways appearing in the host membrane of Plasmodium falciparum infected red blood cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Resistance of glucose-6-phosphate dehydrogenase deficiency to malaria: effects of fava bean hydroxypyrimidine glucosides on Plasmodium falciparum growth in culture and on the phagocytosis of infected cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Hemoglobin degradation in the malaria parasite Plasmodium falciparum: an ordered process in a unique organelle

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

The survival of Plasmodium Under oxidant stress

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Trafficking of malarial proteins to the host cell cytoplasm and erythrocyte surface membrane involves multiple pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Biochemistry of multidrug resistance mediated by the multidrug transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Lipid traffic between high density lipoproteins and Plasmodium falciparum-infected red blood cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Conversion of dihydroorotate to orotate in parasitic protozoa

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Sphingolipid synthesis and membrane formation by Plasmodium.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Control of disease by selective iron depletion: a novel therapeutic strategy utilizing iron chelators

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Plasmodium falciparum: highly mobile small vesicles in the malaria-infected red blood cell cytoplasm.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

The interaction of artemisinin with malarial hemozoin.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Atovaquone - a novel broad-spectrum anti-infective drug.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Point mutations and pyrimethamine resistance in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Xanthones as antimalarial agents; studies of a possible mode of action

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

The effects of antimalarials on the Plasmodium falciparum dihydroorotate dehydrogenase.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Thymidylate synthase-dihydrofolate reductase in protozoa

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Binding of antimalarial drugs to hemozoin from Plasmodium berghei

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Susceptibility to hydrogen peroxide of Plasmodium falciparum infecting glucose-6-phosphate dehydrogenase-deficient erythrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Identification of hemoglobin degradation products in Plasmodium falciparum.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Mitochondria as the site of action of tetracycline on Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

A plastid of probable green algal origin in Apicomplexan parasites.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Glutathione reductase and glutamate dehydrogenase of Plasmodium falciparum, the causative agent of tropical malaria

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

The disposition and effects of two doses of dichloroacetate in adults with severe falciparum malaria

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Purification, characterization and localization of mitochondrial dihydroorotate dehydrogenase in Plasmodium falciparum, human malaria parasite

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

De novo and salvage biosynthesis of pteroylpentaglutamates in the human malaria parasite, Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Pyrimidine biosynthesis in parasitic protozoa: purification of a monofunctional dihydroorotase from Plasmodium berghei and Crithidia fasciculata.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Antimalarial activity of orotate analogs that inhibit dihydroorotase and dihydroorotate dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

The antimalarial action on Plasmodium falciparum of qinghaosu and artesunate in combination with agents which modulate oxidant stress

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Reversal of Plasmodium falciparum resistance to chloroquine in Panamanian Aotus monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Fine Structure of Human MalariaIn Vitro*†

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Purification and properties of Plasmodium falciparum malate dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Sphingolipid synthesis as a target for chemotherapy against malaria parasites

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

A membrane network for nutrient import in red cells infected with the malaria parasite.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Multidrug resistance mediated by the multidrug resistance protein (MRP) gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Targeting signal transduction for disease therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

About hemoglobins, G6PD and parasites in red cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Parasite lactate dehydrogenase as an assay for Plasmodium falciparum drug sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Detailed purine salvage metabolism in and outside the free malarial parasite

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Inhibition of Plasmodium falciparum protein synthesis. Targeting the plastid-like organelle with thiostrepton.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Plastid in human parasites

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

The mode of action of antimalarial endoperoxides

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Iron-dependent free radical generation from the antimalarial agent artemisinin (qinghaosu).

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Plasmodium falciparum glutathione reductase exhibits sequence similarities with the human host enzyme in the core structure but differs at the ligand-binding sites

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Plasmodium falciparum: cyanide-resistant oxygen consumption

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Reversal of mefloquine resistance with penfluridol in isolates of Plasmodium falciparum from south-west Nigeria.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

How plasmodium secures nutrients: new targets for drugs?

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

The plasmodium digestive vacuole: metabolic headquarters and choice drug target

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Hemoglobin catabolism and the killing of intraerythrocytic Plasmodium falciparum by chloroquine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

"Libraries from libraries": chemical transformation of combinatorial libraries to extend the range and repertoire of chemical diversity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Correlation of antimalarial activity of artemisinin derivatives with binding affinity with ferroprotoporphyrin IX

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Formation of haemozoin/beta-haematin under physiological conditions is not spontaneous.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Mating patterns in malaria parasite populations of Papua New Guinea.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Direct access to serum macromolecules by intraerythrocytic malaria parasites

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Taxol arrests the development of blood-stage Plasmodium falciparum in vitro and Plasmodium chabaudi adami in malaria-infected mice

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Depression of Plasmodium falciparum dihydroorotate dehydrogenase activity in in vitro culture by tetracycline

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Chemical synthesis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Recombination associated with replication of malarial mitochondrial DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Plasmodium falciparum: inhibitor sensitivity of the endogenous superoxide dismutase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Molecular targets of 5-fluoroorotate in the human malaria parasite, Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Novel bisquinoline antimalarials. Synthesis, antimalarial activity, and inhibition of haem polymerisation.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Haemozoin formation in malaria parasites: is there a haem polymerase?

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Purification and characterization of Plasmodium berghei DNA topoisomerases I and II: drug action, inhibition of decatenation and relaxation, and stimulation of DNA cleavage.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

The role of the MDR protein in altered drug translocation across tumor cell membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Isolation and characterization of a cysteine proteinase gene of Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

A malarial cysteine proteinase is necessary for hemoglobin degradation by Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Antimalarial effects of peptide inhibitors of a Plasmodium falciparum cysteine proteinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Cloning, sequence determination, and regulation of the ribonucleotide reductase subunits from Plasmodium falciparum: a target for antimalarial therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Natural selection of hemi- and heterozygotes for G6PD deficiency in Africa by resistance to severe malaria

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Purification and characterization of dihydrofolate reductase of Plasmodium falciparum expressed by a synthetic gene in Escherichia coli.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Disulfide-Reductase Inhibitors as Chemotherapeutic Agents: The Design of Drugs for Trypanosomiasis and Malaria

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Interactions between docetaxel (Taxotere) and Plasmodium falciparum-infected erythrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

A model of Plasmodium falciparum lactate dehydrogenase and its implications for the design of improved antimalarials and the enhanced detection of parasitaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Cytotoxic effects of inhibitors of de novo pyrimidine biosynthesis upon Plasmodium falciparum.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Kinetic and molecular properties of dihydrofolate reductase from pyrimethamine-sensitive and pyrimethamine-resistant Plasmodium chabaudi

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Heterologous expression of active thymidylate synthase-dihydrofolate reductase from Plasmodium falciparum.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Antifolate-resistant mutants of Plasmodium falciparum dihydrofolate reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Plasmodium falciparum: asparagine mutant at residue 108 of dihydrofolate reductase is an optimal antifolate-resistant single mutant

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

1 reference

7 January 2021

Chloroquine: mechanism of drug action and resistance in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Inhibition by chloroquine of a novel haem polymerase enzyme activity in malaria trophozoites

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

An iron-carboxylate bond links the heme units of malaria pigment

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Atovaquone, a broad spectrum antiparasitic drug, collapses mitochondrial membrane potential in a malarial parasite

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Antimalarial activity of rifampicin in vitro and in rodent models

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Plasmodium hemozoin formation mediated by histidine-rich proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Primaquine sensitivity. Glucose-6-phosphate dehydrogenase deficiency: an inborn error of metabolism of medical and biological significance

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Pyrimethamine resistant mutations in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Lead discovery of inhibitors of the dihydrofolate reductase domain of Plasmodium falciparum dihydrofolate reductase-thymidylate synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Human malaria parasites in continuous culture

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Primary structure and expression of the dihydropteroate synthetase gene of Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Mutations in dihydropteroate synthase are responsible for sulfone and sulfonamide resistance in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Parasite-induced permeation of nucleosides in Plasmodium falciparum malaria

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Structural features of Plasmodium cytochrome b that may underlie susceptibility to 8-aminoquinolines and hydroxynaphthoquinones

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Cloning and expression in Escherichia coli of a hypoxanthine-guanine phosphoribosyltransferase-encoding cDNA from Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Isolation and sequencing of a cDNA encoding the hypoxanthine-guanine phosphoribosyltransferase from Toxoplasma gondii.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Oxidants, oxidant drugs, and malaria

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Recent developments and rationale towards new strategies for malarial chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Stage-specific transcripts of the Plasmodium falciparum pfmdr 1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Resistance to antifolates in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthetase and dihydrofolate reductase alleles in a large number of field samples of diverse origins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Plasmodium falciparum, P. vivax, and P. malariae: a comparison of the active site properties of plasmepsins cloned and expressed from three different species of the malaria parasite

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

The gene encoding DNA polymerase alpha from Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Amplification of pfmdr 1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Have malaria parasites three genomes?

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Complete gene map of the plastid-like DNA of the malaria parasite Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Alkylation of proteins by artemisinin. Effects of heme, pH, and drug structure

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Molecular cloning of CTP:phosphocholine cytidylyltransferase from Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Glutathione reductase-deficient erythrocytes as host cells of malarial parasites.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

Point mutations in the dihydrofolate reductase-thymidylate synthase gene as the molecular basis for pyrimethamine resistance in Plasmodium falciparum.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2898%2900036-9

7 January 2021

10.1016/S0163-7258(98)00036-9

Identifiers

DOI

1 reference

28 July 2017

1 reference

PubMed ID

10190581