(Q33589502)

28 July 2017

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title

The functions of breast cancer susceptibility gene 1 (BRCA1) product and its associated proteins (English)

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28 July 2017

I Irminger-Finger

1

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28 July 2017

B D Siegel

series ordinal

2

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28 July 2017

W C Leung

series ordinal

3

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28 July 2017

publication date

1 February 1999

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28 July 2017

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28 July 2017

volume

380

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28 July 2017

issue

2

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28 July 2017

page(s)

117-128

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Mouse Brca1: localization sequence analysis and identification of evolutionarily conserved domains

28 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Regulation of BRCA1 and BRCA2 expression in human breast cancer cells by DNA-damaging agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Conservation of function and primary structure in the BRCA1-associated RING domain (BARD1) protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

The cancer-predisposing mutation C61G disrupts homodimer formation in the NH2-terminal BRCA1 RING finger domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Relationships between DNA repair and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Response to radiation therapy and prognosis in breast cancer patients with BRCA1 and BRCA2 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype–phenotype correlation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

BRCA1 required for transcription-coupled repair of oxidative DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Mutations in the BRCA1-associated RING domain (BARD1) gene in primary breast, ovarian and uterine cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Growth retardation and tumour inhibition by BRCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

BRCA1 is associated with the centrosome during mitosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Human BRCA1 inhibits growth in yeast: potential use in diagnostic testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

In vitro repression of Brca1-associated RING domain gene, Bard1, induces phenotypic changes in mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

21 January 2018

DNA repair: RAD alert

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

BRCA1-positive patients are small for gestational age compared with their unaffected relatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Cell cycle-dependent colocalization of BARD1 and BRCA1 proteins in discrete nuclear domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Cancer-susceptibility genes. Gatekeepers and caretakers

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

A human RNA polymerase II complex associated with SRB and DNA-repair proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

CpG methylation within the 5' regulatory region of the BRCA1 gene is tumor specific and includes a putative CREB binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Somatic mutations in the BRCA1 gene in sporadic ovarian tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Evidence for a transcriptional activation function of BRCA1 C-terminal region

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Interaction of short-range repressors with Drosophila CtBP in the embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

BRCA1 regulates p53-dependent gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Preferential allelic expression can lead to reduced expression of BRCA1 in sporadic breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Drosophila CtBP: a Hairy-interacting protein required for embryonic segmentation and hairy-mediated transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Brca2 is coordinately regulated with Brca1 during proliferation and differentiation in mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Association of BRCA1 with Rad51 in mitotic and meiotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

BRCA1 is a component of the RNA polymerase II holoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

The role of DNA repair in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

The carrier frequency of the BRCA1 185delAG mutation is approximately 1 percent in Ashkenazi Jewish individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Brca2 is required for embryonic cellular proliferation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Staurosporine-sensitive protein phosphorylation is required for postreplication DNA repair in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Requirement of proliferating cell nuclear antigen in RAD6-dependent postreplicational DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

BRCA1 binds c-Myc and inhibits its transcriptional and transforming activity in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Distinct transcription start sites generate two forms of BRCA1 mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Complex regulation of the BRCA1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

BRCA1 physically associates with p53 and stimulates its transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Structure of an XRCC1 BRCT domain: a new protein-protein interaction module

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

Transcriptional activation by BRCA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.1999.019

21 January 2018

Identifiers

DOI

10.1515/BC.1999.019

1 reference

28 July 2017

1 reference