(Q33593852)

28 July 2017

5 references

30 June 2022

28 July 2022

29 July 2022

3 October 2022

20 October 2022

Ivermectin to reduce malaria transmission I. Pharmacokinetic and pharmacodynamic considerations regarding efficacy and safety (English)

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28 July 2017

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24 September 2020

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inferred from abstract

1 reference

22 October 2019

Q16869063 (Deleted Item)

object has role

subject heading

object named as

Endectocide

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Carlos Chaccour

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Felix Hammann

object named as

Felix Hammann

series ordinal

2

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author name string

N Regina Rabinovich

series ordinal

3

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PubMed ID

28434401

28 July 2017

language of work or name

1 reference

24 April 2017

13 references

28 July 2017

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11 November 2019

24 July 2020

24 September 2020

30 June 2022

28 July 2022

29 July 2022

3 October 2022

20 October 2022

13 references

28 July 2017

23 March 2019

20 June 2019

27 June 2019

22 October 2019

11 November 2019

24 July 2020

24 September 2020

30 June 2022

28 July 2022

29 July 2022

3 October 2022

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28 July 2017

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161

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Creative Commons Attribution 4.0 International

28 July 2017

12 references

23 March 2019

20 June 2019

27 June 2019

22 October 2019

11 November 2019

24 July 2020

24 September 2020

30 June 2022

28 July 2022

29 July 2022

3 October 2022

on focus list of Wikimedia project

20 October 2022

copyright status

copyrighted

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ScienceSource

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exact match

https://scigraph.springernature.com/pub.10.1186/s12936-017-1801-4

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cites work

Oral, ultra-long-lasting drug delivery: Application toward malaria elimination goals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Efficacy and Safety of High-Dose Ivermectin for Reducing Malaria Transmission (IVERMAL): Protocol for a Double-Blind, Randomized, Placebo-Controlled, Dose-Finding Trial in Western Kenya

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Identification and Validation of Loa loa Microfilaria-Specific Biomarkers: a Rational Design Approach Using Proteomics and Novel Immunoassays

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Insecticide Resistance in African Anopheles Mosquitoes: A Worsening Situation that Needs Urgent Action to Maintain Malaria Control

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Efficacy, Safety, and Pharmacokinetics of Coadministered Diethylcarbamazine, Albendazole, and Ivermectin for Treatment of Bancroftian Filariasis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Age and prior blood feeding of Anopheles gambiae influences their susceptibility and gene expression patterns to ivermectin-containing blood meals

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Establishment of the Ivermectin Research for Malaria Elimination Network: updating the research agenda

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Characterization of the target of ivermectin, the glutamate-gated chloride channel, from Anopheles gambiae

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Point-of-care quantification of blood-borne filarial parasites with a mobile phone microscope

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Screening for an ivermectin slow-release formulation suitable for malaria vector control

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Efficacy and safety of the mosquitocidal drug ivermectin to prevent malaria transmission after treatment: a double-blind, randomized, clinical trial

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Characterizing, controlling and eliminating residual malaria transmission

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

The potential impact of adding ivermectin to a mass treatment intervention to reduce malaria transmission: a modelling study

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

P-glycoproteins and other multidrug resistance transporters in the pharmacology of anthelmintics: Prospects for reversing transport-dependent anthelmintic resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Designing the next generation of medicines for malaria control and eradication

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Ivermectin to reduce malaria transmission: a research agenda for a promising new tool for elimination

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Ivermectin inhibits the sporogony of Plasmodium falciparum in Anopheles gambiae

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Relative neurotoxicity of ivermectin and moxidectin in Mdr1ab (-/-) mice and effects on mammalian GABA(A) channel activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Ivermectin for onchocercal eye disease (river blindness)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Drug screen targeted at Plasmodium liver stages identifies a potent multistage antimalarial drug

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Comparative evaluation of systemic drugs for their effects against Anopheles gambiae

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

The geographic distribution of Loa loa in Africa: results of large-scale implementation of the Rapid Assessment Procedure for Loiasis (RAPLOA)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Endectocides for malaria control

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Mass drug administration of ivermectin in south-eastern Senegal reduces the survivorship of wild-caught, blood fed malaria vectors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

The effect of oral anthelmintics on the survivorship and re-feeding frequency of anthropophilic mosquito disease vectors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Membrane transporters in drug development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Toxicity of bloodmeals from ivermectin-treated cattle to Anopheles gambiae s.l.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Efficacy of ivermectin and albendazole alone and in combination for treatment of soil-transmitted helminths in pregnancy and adverse events: a randomized open label controlled intervention trial in Masindi district, western Uganda

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

The pharmacokinetics and interactions of ivermectin in humans--a mini-review

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Pharmacogenetics: it's not just about ivermectin in collies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Crusted scabies: clinical and immunological findings in seventy-eight patients and a review of the literature

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Adverse systemic reactions to treatment of onchocerciasis with ivermectin at normal and high doses given annually or three-monthly

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Possible pathogenic pathways in the adverse clinical events seen following ivermectin administration to onchocerciasis patients

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Inadvertent exposure of pregnant women to ivermectin and albendazole during mass drug administration for lymphatic filariasis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

21 June 2018

Ivermectin for scabies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Deaths associated with ivermectin for scabies.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Serious reactions after mass treatment of onchocerciasis with ivermectin in an area endemic for Loa loa infection.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Environmental effects of the usage of avermectins in livestock

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Absence of any adverse effect of inadvertent ivermectin treatment during pregnancy.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Colonisation and degradation of dung pats after subcutaneous treatment of cattle with ivermectin or levamisole.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Structure and activity of avermectins and milbemycins in animal health

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Environmental consequences of treating cattle with the antiparasitic drug ivermectin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Comparative in vivo and in vitro metabolism of ivermectin in steers, sheep, swine, and rat.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

The relative systemic availability of ivermectin after administration as capsule, tablet, and oral solution.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Effects of ivermectin on reproduction and neonatal toxicity in rats

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

A prospective study in high risk subjects of electrocardiographic changes with ivermectin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Pregnancy outcome after inadvertent ivermectin treatment during community-based distribution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Ivermectin uptake and distribution in the plasma and tissue of Sudanese and Mexican patients infected with Onchocerca volvulus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Ivermectin and pregnancy in mass treatment in Mali

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Improvement in seizures after ivermectin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Parenteral ivermectin in Strongyloides hyperinfection.

21 June 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12936-017-1801-4

Treatment of human disseminated strongyloidiasis with a parenteral veterinary formulation of ivermectin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12936-017-1801-4

The lack of influence of food and local alcoholic brew on the blood level of Mectizan(®) (ivermectin).

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12936-017-1801-4

Effect of high-fat meal intake on the pharmacokinetic profile of ivermectin in Japanese patients with scabies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12936-017-1801-4

Ivermectin interacts with human ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12936-017-1801-4

The ontogeny of P-glycoprotein in the developing human blood-brain barrier: implication for opioid toxicity in neonates

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12936-017-1801-4

Identification of cytochrome P4503A4 as the major enzyme responsible for the metabolism of ivermectin by human liver microsomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12936-017-1801-4

Cytochrome P-450 expression in sudden infant death syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12936-017-1801-4

Ketoconazole increases the plasma levels of ivermectin in sheep.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12936-017-1801-4

Safety, tolerability, and pharmacokinetics of escalating high doses of ivermectin in healthy adult subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12936-017-1801-4

Ivermectin: does P-glycoprotein play a role in neurotoxicity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12936-017-1801-4

Ivermectin levels in human breastmilk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12936-017-1801-4

Case 23-2012: A man with abdominal pain and weight loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12936-017-1801-4

Treatment of scabies with oral ivermectin in 15 infants: a retrospective study on tolerance and efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12936-017-1801-4

Deaths associated with ivermectin treatment of scabies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12936-017-1801-4

The effects of high-dose ivermectin regimens on Onchocerca volvulus in onchocerciasis patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS12936-017-1801-4

Changes in the use profile of Mectizan: 1987-1997.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Developmental expression of CYP2C and CYP2C-dependent activities in the human liver: in-vivo/in-vitro correlation and inducibility.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

The chemotherapy of onchocerciasis. XIX: The clinical and laboratory tolerance of high dose ivermectin.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Effects of ivermectin in canine blood on Anopheles quadrimaculatus, Aedes albopictus and Culex salinarius.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Ivermectin detection in serum of onchocerciasis patients: relationship to adverse reactions.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5402169

Multiple oral dosing of ketoconazole increases dog exposure to ivermectin

30 October 2018

1 reference

12 December 2020

Ivermectin to reduce malaria transmission II. Considerations regarding clinical development pathway

1 reference

12 December 2020

Ivermectin distribution in the plasma and tissues of patients infected with Onchocerca volvulus

1 reference

12 December 2020

Deaths associated with ivermectin for scabies

1 reference

12 December 2020

Deaths associated with ivermectin for scabies

1 reference

12 December 2020

10.1186/S12936-017-1801-4

Identifiers

DOI

1 reference

PubMed ID

28434401

Dimensions Publication ID

28 July 2017

1 reference

https://scigraph.springernature.com/pub.10.1186/s12936-017-1801-4

9 September 2019

1 reference

28 July 2017

1 reference

PubMed ID

28434401