(Q33597044)

28 July 2017

title

Ectopic T-cell specificity and absence of perforin and granzyme B alleviate neural damage in oligodendrocyte mutant mice (English)

1 reference

28 July 2017

1 reference

4

Klaus-Armin Nave

1 reference

28 July 2017

Rudolf Martini

5

0 references

Chi Wang Ip

object named as

Chi Wang Ip

series ordinal

2

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author name string

Antje Kroner

series ordinal

1

1 reference

28 July 2017

Johannes Thalhammer

series ordinal

3

1 reference

28 July 2017

language of work or name

English

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publication date

30 December 2009

1 reference

The American Journal of Pathology

28 July 2017

published in

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28 July 2017

volume

176

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28 July 2017

issue

2

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28 July 2017

page(s)

549-555

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describes a project that uses

28 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2808063/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Pathogenic CD8(+) T cells in multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

Demyelinated axons and motor function are protected by genetic deletion of perforin in a mouse model of multiple sclerosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

PD-1 regulates neural damage in oligodendroglia-induced inflammation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

The role of CD8 suppressors versus destructors in autoimmune central nervous system inflammation

21 June 2018

1 reference

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Relapses in multiple sclerosis are associated with increased CD8+ T-cell mediated cytotoxicity in CSF

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

Death by a thousand cuts: granzyme pathways of programmed cell death

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

Mechanisms of granule-dependent killing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

CD8+ T cells in inflammatory demyelinating disease.

21 June 2018

1 reference

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Absence of perforin expression confers axonal protection despite demyelination.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

Role of immune cells in animal models for inherited peripheral neuropathies

21 June 2018

1 reference

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Induction of experimental autoimmune encephalomyelitis in transgenic mice expressing ovalbumin in oligodendrocytes

21 June 2018

1 reference

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Granzyme B binds to target cells mostly by charge and must be added at the same time as perforin to trigger apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion

21 June 2018

1 reference

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Multiple sclerosis: brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid and blood

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

T-cell-mediated autoimmunity: novel techniques to characterize autoreactive T-cell receptors

21 June 2018

1 reference

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Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases.

21 June 2018

1 reference

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Bone marrow transfer from wild-type mice reverts the beneficial effect of genetically mediated immune deficiency in myelin mutants.

21 June 2018

1 reference

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T cells compete for access to antigen-bearing antigen-presenting cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction

21 June 2018

1 reference

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Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination

21 June 2018

1 reference

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Late-onset neurodegeneration in mice with increased dosage of the proteolipid protein gene

21 June 2018

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T cell receptor antagonist peptides induce positive selection

21 June 2018

1 reference

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Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

Naive CD8 T-cells initiate spontaneous autoimmunity to a sequestered model antigen of the central nervous system.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

Transition from enhanced T cell infiltration to inflammation in the myelin-degenerative central nervous system.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

Sialoadhesin deficiency ameliorates myelin degeneration and axonopathic changes in the CNS of PLP overexpressing mice.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

Immune cells contribute to myelin degeneration and axonopathic changes in mice overexpressing proteolipid protein in oligodendrocytes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

Perforin triggers a plasma membrane-repair response that facilitates CTL induction of apoptosis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

Primary progressive multiple sclerosis as a phenotype of a PLP1 gene mutation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

Neuroprotective effect of the immune system in a mouse model of severe dysmyelinating hereditary neuropathy: enhanced axonal degeneration following disruption of the RAG-1 gene.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

Preserved myelin integrity and reduced axonopathy in connexin32-deficient mice lacking the recombination activating gene-1.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation?

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

Premature arrest of myelin formation in transgenic mice with increased proteolipid protein gene dosage

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808063

Granzyme B mediates neurotoxicity through a G-protein-coupled receptor

30 October 2018

1 reference

12 December 2020

Steroid-responsive neurologic relapses in a child with a proteolipid protein-1 mutation

1 reference

12 December 2020

Clonal expansions of pathogenic CD8+ effector cells in the CNS of myelin mutant mice

1 reference

12 December 2020

The co-inhibitory molecule PD-1 modulates disease severity in a model for an inherited, demyelinating neuropathy

1 reference

12 December 2020

10.2353/AJPATH.2010.090722

Identifiers

DOI

1 reference

28 July 2017

1 reference

28 July 2017

1 reference