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Costimulatory regulation of T cell function.
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10209159
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10209159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
review article
1 reference
stated in
Europe PubMed Central
title
Costimulatory regulation of T cell function
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10209159
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10209159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
main subject
cell function
0 references
author
James P. Allison
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10209159
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10209159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
author name string
C A Chambers
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10209159
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10209159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
publication date
1 April 1999
1 reference
stated in
Europe PubMed Central
PubMed ID
10209159
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10209159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
published in
Current Opinion in Cell Biology
1 reference
stated in
Europe PubMed Central
PubMed ID
10209159
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10209159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
volume
11
1 reference
stated in
Europe PubMed Central
PubMed ID
10209159
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10209159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
page(s)
203-210
1 reference
stated in
Europe PubMed Central
PubMed ID
10209159
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10209159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10209159
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10209159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
cites work
CD28/B7 system of T cell costimulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Solution structure of human CTLA-4 and delineation of a CD80/CD86 binding site conserved in CD28
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Co-stimulation in T cell responses.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CTLA-4 can function as a negative regulator of T cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytotoxic T lymphocyte-associated molecule-4, a high-avidity receptor for CD80 and CD86, contains an intracellular localization motif in its cytoplasmic tail
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The medium subunits of adaptor complexes recognize distinct but overlapping sets of tyrosine-based sorting signals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of CTLA-4 with AP50, a clathrin-coated pit adaptor protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of the cytoplasmic tail of CTLA-4 (CD152) with a clathrin-associated protein is negatively regulated by tyrosine phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Src family tyrosine kinases associate with and phosphorylate CTLA-4 (CD152).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for CD40 ligand in costimulation induction, T cell activation, and experimental allergic encephalomyelitis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD40 ligand-dependent T cell activation: requirement of B7-CD28 signaling through CD40.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Help for cytotoxic-T-cell responses is mediated by CD40 signalling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CTLA-4-B7 interaction is sufficient to costimulate T cell clonal expansion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
B7-CTLA4 interaction enhances both production of antitumor cytotoxic T lymphocytes and resistance to tumor challenge.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhancement of antitumor immunity by CTLA-4 blockade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CTLA-4 blockade synergizes with tumor-derived granulocyte-macrophage colony-stimulating factor for treatment of an experimental mammary carcinoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytotoxic T lymphocyte antigen 4 (CTLA4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA4 can function independently of CD28.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
B7-1 engagement of cytotoxic T lymphocyte antigen 4 inhibits T cell activation in the absence of CD28.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protective immunity to nematode infection is induced by CTLA-4 blockade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of CTLA-4 in the regulation and initiation of T-cell responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thymocyte development is normal in CTLA-4-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lymphoproliferation in CTLA-4-deficient mice is mediated by costimulation-dependent activation of CD4+ T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Normal thymic selection, normal viability and decreased lymphoproliferation in T cell receptor-transgenic CTLA-4-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4(+) T cell responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MHC Class II Molecules Are Not Required for Survival of Newly Generated CD4+ T Cells, but Affect Their Long-Term Life Span
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential requirements for survival and proliferation of CD8 naïve or memory T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of naive, memory and effector T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of a Cdk2 inhibitor during interleukin 2-induced proliferation of human T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
JNK is involved in signal integration during costimulation of T lymphocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD28 affects the earliest signaling events generated by TCR engagement.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CTLA4 mediates antigen-specific apoptosis of human T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fas-independent death of activated CD4(+) T lymphocytes induced by CTLA-4 crosslinking
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CTLA-4 ligation blocks CD28-dependent T cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Engagement of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) induces transforming growth factor beta (TGF-beta) production by murine CD4(+) T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytotoxic T lymphocyte antigen 4 (CTLA-4) interferes with extracellular signal-regulated kinase (ERK) and Jun NH2-terminal kinase (JNK) activation, but does not affect phosphorylation of T cell receptor zeta and ZAP70.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of immune responses by TGF-beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell antigen receptor signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of tyrosine phosphorylation and PTP-1C in CTLA-4 signal transduction.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular basis of T cell inactivation by CTLA-4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Making the T cell receptor go the distance: a topological view of T cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Membrane compartmentation is required for efficient T cell activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Engagement of GPI-linked CD48 contributes to TCR signals and cytoskeletal reorganization: a role for lipid rafts in T cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective modulation of protein kinase C-theta during T-cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Three-dimensional segregation of supramolecular activation clusters in T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A receptor/cytoskeletal movement triggered by costimulation during T cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2980027-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0955-0674(99)80027-1
1 reference
stated in
Europe PubMed Central
PubMed ID
10209159
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10209159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
PubMed ID
10209159
1 reference
stated in
Europe PubMed Central
PubMed ID
10209159
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10209159%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 December 2019
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