(Q33599159)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010651%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

Computational modeling to accelerate the identification of substrates and inhibitors for transporters that affect drug disposition (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010651%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010651%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Peter W. Swaan

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010651%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

author name string

J E Polli

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010651%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

S H Wright

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010651%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

language of work or name

English

0 references

publication date

26 September 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010651%20AND%20SRC:MED&resulttype=core&format=json

Clinical Pharmacology & Therapeutics

9 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010651%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

volume

92

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010651%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010651%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

page(s)

661-665

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010651%20AND%20SRC:MED&resulttype=core&format=json

Molecular determinants of ligand selectivity for the human multidrug and toxin extruder proteins MATE1 and MATE2-K.

9 March 2020

cites work

1 reference

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A substrate pharmacophore for the human organic cation/carnitine transporter identifies compounds associated with rhabdomyolysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Predicting P-glycoprotein-mediated drug transport based on support vector machine and three-dimensional crystal structure of P-glycoprotein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Molecular analysis and structure-activity relationship modeling of the substrate/inhibitor interaction site of plasma membrane monoamine transporter.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Proton pump inhibitors inhibit metformin uptake by organic cation transporters (OCTs)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

In silico repositioning of approved drugs for rare and neglected diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Structural determinants for transport across the intestinal bile acid transporter using C-24 bile acid conjugates.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Quantitative structure activity relationship for inhibition of human organic cation/carnitine transporter

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Using Open Source Computational Tools for Predicting Human Metabolic Stability and Additional Absorption, Distribution, Metabolism, Excretion, and Toxicity Properties

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Towards interoperable and reproducible QSAR analyses: Exchange of datasets

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Membrane transporters in drug development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Computational models for drug inhibition of the human apical sodium-dependent bile acid transporter

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Novel inhibitors of human organic cation/carnitine transporter (hOCTN2) via computational modeling and in vitro testing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Bacterial peptide recognition and immune activation facilitated by human peptide transporter PEPT2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Future directions for drug transporter modelling.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

A global drug inhibition pattern for the human ATP-binding cassette transporter breast cancer resistance protein (ABCG2).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

In vitro and pharmacophore-based discovery of novel hPEPT1 inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Comparative pharmacophore modeling of organic anion transporting polypeptides: a meta-analysis of rat Oatp1a1 and human OATP1B1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Pharmacogenomics and systems biology of membrane transporters

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Polyspecific organic cation transporters: their functions and interactions with drugs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Structural determinants of P-glycoprotein-mediated transport of glucocorticoids

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Pharmacogenetics of hepatocellular transporters

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

The superfamily of organic anion transporting polypeptides

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Structural biology and function of solute transporters: implications for identifying and designing substrates

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Application of three-dimensional quantitative structure-activity relationships of P-glycoprotein inhibitors and substrates

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Modeling of active transport systems

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Progress in predicting human ADME parameters in silico

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4018235

Targeting Drug Transporters – Combining In Silico and In Vitro Approaches to Predict In Vivo

21 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.164

Molecular determinants of substrate/inhibitor binding to the human and rabbit renal organic cation transporters hOCT2 and rbOCT2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.164

Influence of molecular structure on substrate binding to the human organic cation transporter, hOCT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.164

Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.164

Rapid Identification of P-glycoprotein Substrates and Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.164

Molecular requirements of the human nucleoside transporters hCNT1, hCNT2, and hENT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.164

Integrated in silico-in vitro strategy for addressing cytochrome P450 3A4 time-dependent inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.164

21 January 2018

Identifiers

DOI

10.1038/CLPT.2012.164

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010651%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010651%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

PubMed publication ID

23010651

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23010651%20AND%20SRC:MED&resulttype=core&format=json